Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985686527> ?p ?o ?g. }
- W1985686527 endingPage "16863" @default.
- W1985686527 startingPage "16861" @default.
- W1985686527 abstract "Here we report a new methodology for mRNA-programmed synthesis of peptoids and peptoid-peptide hybrids by means of translation machinery under the reprogrammed genetic code. We initially screened N-substituted glycines (rGly) for their single incorporation into a nascent peptide chain and found translation machinery accepts a variety of rGly for elongation. Moreover, we have shown consecutive elongations of rGly and mRNA-directed synthesis of cyclic peptoid-peptide hybrids. This methodology offers a powerful tool for mRNA-programmed library synthesis of peptoids and peptoid-peptide hybrids with linear and cyclic scaffolds, potentially leading to the discovery of drug candidates with proteolytic stability and membrane permeability." @default.
- W1985686527 created "2016-06-24" @default.
- W1985686527 creator A5010970429 @default.
- W1985686527 creator A5017224243 @default.
- W1985686527 creator A5076038052 @default.
- W1985686527 date "2008-11-19" @default.
- W1985686527 modified "2023-10-18" @default.
- W1985686527 title "Ribosomal Synthesis of Polypeptoids and Peptoid−Peptide Hybrids" @default.
- W1985686527 cites W1555270229 @default.
- W1985686527 cites W1587481053 @default.
- W1985686527 cites W1964302063 @default.
- W1985686527 cites W1969303801 @default.
- W1985686527 cites W1971447541 @default.
- W1985686527 cites W1971486985 @default.
- W1985686527 cites W1973707642 @default.
- W1985686527 cites W1974357725 @default.
- W1985686527 cites W1978667812 @default.
- W1985686527 cites W1979755475 @default.
- W1985686527 cites W1982949762 @default.
- W1985686527 cites W1983111757 @default.
- W1985686527 cites W1986861718 @default.
- W1985686527 cites W1987177052 @default.
- W1985686527 cites W1990557050 @default.
- W1985686527 cites W1993016234 @default.
- W1985686527 cites W1993111592 @default.
- W1985686527 cites W2006437356 @default.
- W1985686527 cites W2007427026 @default.
- W1985686527 cites W2009181811 @default.
- W1985686527 cites W2015887575 @default.
- W1985686527 cites W2017435817 @default.
- W1985686527 cites W2017947525 @default.
- W1985686527 cites W2023212741 @default.
- W1985686527 cites W2026089250 @default.
- W1985686527 cites W2028493269 @default.
- W1985686527 cites W2031291845 @default.
- W1985686527 cites W2032771203 @default.
- W1985686527 cites W2035579869 @default.
- W1985686527 cites W2049575563 @default.
- W1985686527 cites W2055760720 @default.
- W1985686527 cites W2057288644 @default.
- W1985686527 cites W2063804783 @default.
- W1985686527 cites W2065397247 @default.
- W1985686527 cites W2065609269 @default.
- W1985686527 cites W2068527752 @default.
- W1985686527 cites W2071190573 @default.
- W1985686527 cites W2076980750 @default.
- W1985686527 cites W2078405116 @default.
- W1985686527 cites W2079838527 @default.
- W1985686527 cites W2088161405 @default.
- W1985686527 cites W2094535327 @default.
- W1985686527 cites W2099965964 @default.
- W1985686527 cites W2105161156 @default.
- W1985686527 cites W2122080717 @default.
- W1985686527 cites W2137062180 @default.
- W1985686527 cites W2140955733 @default.
- W1985686527 cites W2142759234 @default.
- W1985686527 cites W2147862471 @default.
- W1985686527 cites W2148771787 @default.
- W1985686527 cites W2162250498 @default.
- W1985686527 cites W4256059718 @default.
- W1985686527 cites W89221041 @default.
- W1985686527 doi "https://doi.org/10.1021/ja806998v" @default.
- W1985686527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19053417" @default.
- W1985686527 hasPublicationYear "2008" @default.
- W1985686527 type Work @default.
- W1985686527 sameAs 1985686527 @default.
- W1985686527 citedByCount "103" @default.
- W1985686527 countsByYear W19856865272012 @default.
- W1985686527 countsByYear W19856865272013 @default.
- W1985686527 countsByYear W19856865272014 @default.
- W1985686527 countsByYear W19856865272015 @default.
- W1985686527 countsByYear W19856865272016 @default.
- W1985686527 countsByYear W19856865272017 @default.
- W1985686527 countsByYear W19856865272018 @default.
- W1985686527 countsByYear W19856865272019 @default.
- W1985686527 countsByYear W19856865272020 @default.
- W1985686527 countsByYear W19856865272021 @default.
- W1985686527 countsByYear W19856865272022 @default.
- W1985686527 countsByYear W19856865272023 @default.
- W1985686527 crossrefType "journal-article" @default.
- W1985686527 hasAuthorship W1985686527A5010970429 @default.
- W1985686527 hasAuthorship W1985686527A5017224243 @default.
- W1985686527 hasAuthorship W1985686527A5076038052 @default.
- W1985686527 hasConcept C104317684 @default.
- W1985686527 hasConcept C105580179 @default.
- W1985686527 hasConcept C10853874 @default.
- W1985686527 hasConcept C124790011 @default.
- W1985686527 hasConcept C149364088 @default.
- W1985686527 hasConcept C185592680 @default.
- W1985686527 hasConcept C21951064 @default.
- W1985686527 hasConcept C2779281246 @default.
- W1985686527 hasConcept C2780474982 @default.
- W1985686527 hasConcept C3675279 @default.
- W1985686527 hasConcept C515207424 @default.
- W1985686527 hasConcept C55493867 @default.
- W1985686527 hasConcept C60984968 @default.
- W1985686527 hasConcept C67905577 @default.
- W1985686527 hasConcept C70721500 @default.