FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989053556> ?p ?o ?g. }

• W1989053556 endingPage "826" @default.
• W1989053556 startingPage "820" @default.
• W1989053556 abstract "✓ From March, 1984, through June, 1987, 21 newly diagnosed children with high-risk medulloblastoma (Chang Stage T 3 to T 4 ) were treated on a 9-week postoperative, pre-irradiation chemotherapy regimen consisting of vincristine and cisplatin. The children over 2 years old then received radiation therapy. Six infants (aged 6 to 18 months) were maintained on chemotherapy consisting of MOP (nitrogen mustard, vincristine, and procarbazine) until the age of 2 years, at which time they were referred for irradiation. Of 13 children with measurable disease following surgery, five showed a definite response on computerized tomography scans to vincristine and cisplatin (one complete response and four partial responses) and five others showed clear marginal responses. Four of the six infants were disease-free at 19, 32, 35, and 57 months from diagnosis. One infant developed progressive disease at the completion of the vincristine and cisplatin course, and a second infant had progression during MOP administration. Three of the 21 children developed hearing loss within the speech frequencies during cisplatin treatments, but there were no other major toxicities. Fifteen children remained disease-free with a median follow-up period of 35 months (range 19 to 57 months). Chemotherapy given between surgery and radiotherapy may allow for the direct evaluation of a specific drug regimen and permit the postponement of radiation therapy in infants. Pre-irradiation vincristine and cisplatin was well tolerated and effective in shrinking the tumor in most children with medulloblastoma. Such chemotherapy regimens have the potential for extending long-term survival in high-risk children." @default.
• W1989053556 created "2016-06-24" @default.
• W1989053556 creator A5001528733 @default.
• W1989053556 creator A5029945563 @default.
• W1989053556 creator A5059295841 @default.
• W1989053556 creator A5071918907 @default.
• W1989053556 creator A5072375420 @default.
• W1989053556 creator A5076968637 @default.
• W1989053556 creator A5082614208 @default.
• W1989053556 creator A5087385160 @default.
• W1989053556 creator A5090126569 @default.
• W1989053556 date "1989-12-01" @default.
• W1989053556 modified "2023-09-26" @default.
• W1989053556 title "Pre-irradiation chemotherapy for infants and children with medulloblastoma: a preliminary report" @default.
• W1989053556 cites W1509802320 @default.
• W1989053556 cites W1969388710 @default.
• W1989053556 cites W1973694210 @default.
• W1989053556 cites W1974965723 @default.
• W1989053556 cites W1976552389 @default.
• W1989053556 cites W1977826988 @default.
• W1989053556 cites W1978161696 @default.
• W1989053556 cites W1985515235 @default.
• W1989053556 cites W1986305277 @default.
• W1989053556 cites W1990298357 @default.
• W1989053556 cites W1991896137 @default.
• W1989053556 cites W2019232415 @default.
• W1989053556 cites W2026518062 @default.
• W1989053556 cites W2034622647 @default.
• W1989053556 cites W2036371914 @default.
• W1989053556 cites W2037946157 @default.
• W1989053556 cites W2043432825 @default.
• W1989053556 cites W2070068475 @default.
• W1989053556 cites W2084540628 @default.
• W1989053556 cites W2087931831 @default.
• W1989053556 cites W2090595805 @default.
• W1989053556 cites W2091328743 @default.
• W1989053556 cites W2141151491 @default.
• W1989053556 cites W2144196995 @default.
• W1989053556 cites W2168405626 @default.
• W1989053556 cites W2285560870 @default.
• W1989053556 cites W2491874531 @default.
• W1989053556 doi "https://doi.org/10.3171/jns.1989.71.6.0820" @default.
• W1989053556 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2585072" @default.
• W1989053556 hasPublicationYear "1989" @default.
• W1989053556 type Work @default.
• W1989053556 sameAs 1989053556 @default.
• W1989053556 citedByCount "40" @default.
• W1989053556 countsByYear W19890535562019 @default.
• W1989053556 crossrefType "journal-article" @default.
• W1989053556 hasAuthorship W1989053556A5001528733 @default.
• W1989053556 hasAuthorship W1989053556A5029945563 @default.
• W1989053556 hasAuthorship W1989053556A5059295841 @default.
• W1989053556 hasAuthorship W1989053556A5071918907 @default.
• W1989053556 hasAuthorship W1989053556A5072375420 @default.
• W1989053556 hasAuthorship W1989053556A5076968637 @default.
• W1989053556 hasAuthorship W1989053556A5082614208 @default.
• W1989053556 hasAuthorship W1989053556A5087385160 @default.
• W1989053556 hasAuthorship W1989053556A5090126569 @default.
• W1989053556 hasConcept C141071460 @default.
• W1989053556 hasConcept C142724271 @default.
• W1989053556 hasConcept C187212893 @default.
• W1989053556 hasConcept C2776694085 @default.
• W1989053556 hasConcept C2776755627 @default.
• W1989053556 hasConcept C2778239845 @default.
• W1989053556 hasConcept C2778336483 @default.
• W1989053556 hasConcept C2779112685 @default.
• W1989053556 hasConcept C2779429289 @default.
• W1989053556 hasConcept C2779434656 @default.
• W1989053556 hasConcept C2780789225 @default.
• W1989053556 hasConcept C2781413609 @default.
• W1989053556 hasConcept C509974204 @default.
• W1989053556 hasConcept C71924100 @default.
• W1989053556 hasConceptScore W1989053556C141071460 @default.
• W1989053556 hasConceptScore W1989053556C142724271 @default.
• W1989053556 hasConceptScore W1989053556C187212893 @default.
• W1989053556 hasConceptScore W1989053556C2776694085 @default.
• W1989053556 hasConceptScore W1989053556C2776755627 @default.
• W1989053556 hasConceptScore W1989053556C2778239845 @default.
• W1989053556 hasConceptScore W1989053556C2778336483 @default.
• W1989053556 hasConceptScore W1989053556C2779112685 @default.
• W1989053556 hasConceptScore W1989053556C2779429289 @default.
• W1989053556 hasConceptScore W1989053556C2779434656 @default.
• W1989053556 hasConceptScore W1989053556C2780789225 @default.
• W1989053556 hasConceptScore W1989053556C2781413609 @default.
• W1989053556 hasConceptScore W1989053556C509974204 @default.
• W1989053556 hasConceptScore W1989053556C71924100 @default.
• W1989053556 hasIssue "6" @default.
• W1989053556 hasLocation W19890535561 @default.
• W1989053556 hasLocation W19890535562 @default.
• W1989053556 hasOpenAccess W1989053556 @default.
• W1989053556 hasPrimaryLocation W19890535561 @default.
• W1989053556 hasRelatedWork W1884303117 @default.
• W1989053556 hasRelatedWork W1964694082 @default.
• W1989053556 hasRelatedWork W1976996740 @default.
• W1989053556 hasRelatedWork W1989053556 @default.
• W1989053556 hasRelatedWork W2007292210 @default.
• W1989053556 hasRelatedWork W2033302920 @default.
• W1989053556 hasRelatedWork W2410654427 @default.

• next