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• W1992051294 abstract "Keeping in view the anticancer nature of psyllium and methotrexate, psyllium, if suitably tailored to prepare the hydrogels, can act as the potential candidate for the slow drug delivery systems for GI tract. Therefore, the present study is an attempt to modify the psyllium for developing the hydrogels meant for delivery of methotrexate in controlled and sustained manner. The present article discusses the synthesis and characterization of the psy-cl-poly(AAm-co-AAc) hydrogels prepared by chemical crosslinking methods. These hydrogels have been characterized with SEMs, FTIR, TGA, XRD and swelling studies. The swelling and drug release behavior of hydrogels has been determined in solution of different pH. The results indicate that the drug release from the polymeric matrix follows Fickian diffusion mechanism in pH 7.4 buffer." @default.
• W1992051294 created "2016-06-24" @default.
• W1992051294 creator A5010737643 @default.
• W1992051294 creator A5047591335 @default.
• W1992051294 date "2014-04-01" @default.
• W1992051294 modified "2023-10-01" @default.
• W1992051294 title "Polysaccharide based hydrogels as controlled drug delivery system for GIT cancer" @default.
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• W1992051294 doi "https://doi.org/10.1016/j.ijbiomac.2014.02.004" @default.
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