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- W2000202222 abstract "Osmium tetroxide complexes with nitrogen ligands [Os(VIII)L] have been widely applied as probes of the DNA structure and as electroactive labels of DNA. Here we describe the electrochemical behavior of Os(VIII)2,2-bipyridine (Os, bipy)-base-labeled nucleosides. We show that electroactive label can be introduced also in the nucleoside ribose residues using six-valent osmium complex. Cyclic voltammograms of sugar-Os(VI)-modified ribosides are similar but not identical to those of the base-modified ribosides. Our results showing the electroactivity of sugar modified ribosides pave the way to facile end-labeling of RNA." @default.
- W2000202222 created "2016-06-24" @default.
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- W2000202222 date "2007-06-01" @default.
- W2000202222 modified "2023-10-17" @default.
- W2000202222 title "Covalent Labeling of Nucleosides with VIII- and VI-Valent Osmium Complexes" @default.
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- W2000202222 doi "https://doi.org/10.1002/elan.200703848" @default.
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