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- W2010045305 abstract "To study the role of dopamine D1 and D2 receptors in the ventrolateral striatum in feeding behavior, a D2 receptor agonist (CY 2082-243), a D1 receptor antagonist (SCH 23390), a D2 receptor agonist (quinpirole), and a D2 receptor antagonist [(−)-sulpiride] were perfused via a microdialysis probe into the ventrolateral striatum of rats fasted for 22 h. Then the rats were allowed to feed freely for 6 h. Sulpiride perfusion at a high concentration suppressed food and water intake significantly, whereas dopamine release and the levels of DOPAC and HVA were increased at all concentrations. In contrast, quinpirole perfusion at a high concentration increased food intake by 41%. Dopamine release and the levels of DOPAC and HVA were decreased at all concentrations. On the other hand, neither CY 208–243 nor SCH 23390 changed food intake or dopamine release, but both drugs decreased water intake. These results suggest that D2 receptors in the ventrolateral striatum have a more important role than D1 receptors in the feeding behavior of rats." @default.
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- W2010045305 date "1995-02-01" @default.
- W2010045305 modified "2023-09-27" @default.
- W2010045305 title "D2 receptors in the ventrolateral striatum are involved in feeding behavior in rats" @default.
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- W2010045305 doi "https://doi.org/10.1016/0091-3057(94)00275-n" @default.
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