FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013670462> ?p ?o ?g. }

• W2013670462 endingPage "405" @default.
• W2013670462 startingPage "401" @default.
• W2013670462 abstract "Because the up-regulation of telomerase in most cancer tissues is considered to be responsible for the unlimited proliferation of cancer cells, suppression of telomerase activity is an attractive potential target for cancer therapy. The mechanism for the activation of telomerase in cancer cells, however, is still unclear. In the present study, we demonstrated that Zn induces an enhancement of telomerase activity in the human renal cell carcinoma (NRC-12) and prostatic cancer (DU145) cell lines. The maximum elevation of the activity was observed 6 hr after treatment with 100 microM Zn; it was diminished by the addition of either metal chelator or cycloheximide. Other metals such as Cd and Cu also enhanced telomerase activity but to a lesser extent, and no correlation between the activation of telomerase and the induction of metallothionein was observed. Our findings provide the first evidence that metals, especially Zn, can modulate telomerase activity in cancer cells." @default.
• W2013670462 created "2016-06-24" @default.
• W2013670462 creator A5012037110 @default.
• W2013670462 creator A5041089024 @default.
• W2013670462 creator A5047414438 @default.
• W2013670462 creator A5051689922 @default.
• W2013670462 creator A5059356860 @default.
• W2013670462 creator A5080392296 @default.
• W2013670462 creator A5088501475 @default.
• W2013670462 date "2000-02-01" @default.
• W2013670462 modified "2023-10-12" @default.
• W2013670462 title "Modulation of telomerase activity by zinc in human prostatic and renal cancer cells" @default.
• W2013670462 cites W1547608553 @default.
• W2013670462 cites W1943607432 @default.
• W2013670462 cites W1983366193 @default.
• W2013670462 cites W2004561527 @default.
• W2013670462 cites W2013880323 @default.
• W2013670462 cites W2045702252 @default.
• W2013670462 cites W2067224785 @default.
• W2013670462 cites W2110652761 @default.
• W2013670462 cites W2139793739 @default.
• W2013670462 cites W2143859021 @default.
• W2013670462 cites W2169455407 @default.
• W2013670462 cites W4231673260 @default.
• W2013670462 doi "https://doi.org/10.1016/s0006-2952(99)00334-2" @default.
• W2013670462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10644048" @default.
• W2013670462 hasPublicationYear "2000" @default.
• W2013670462 type Work @default.
• W2013670462 sameAs 2013670462 @default.
• W2013670462 citedByCount "74" @default.
• W2013670462 countsByYear W20136704622012 @default.
• W2013670462 countsByYear W20136704622013 @default.
• W2013670462 countsByYear W20136704622014 @default.
• W2013670462 countsByYear W20136704622015 @default.
• W2013670462 countsByYear W20136704622016 @default.
• W2013670462 countsByYear W20136704622017 @default.
• W2013670462 countsByYear W20136704622018 @default.
• W2013670462 countsByYear W20136704622019 @default.
• W2013670462 countsByYear W20136704622020 @default.
• W2013670462 countsByYear W20136704622021 @default.
• W2013670462 countsByYear W20136704622022 @default.
• W2013670462 crossrefType "journal-article" @default.
• W2013670462 hasAuthorship W2013670462A5012037110 @default.
• W2013670462 hasAuthorship W2013670462A5041089024 @default.
• W2013670462 hasAuthorship W2013670462A5047414438 @default.
• W2013670462 hasAuthorship W2013670462A5051689922 @default.
• W2013670462 hasAuthorship W2013670462A5059356860 @default.
• W2013670462 hasAuthorship W2013670462A5080392296 @default.
• W2013670462 hasAuthorship W2013670462A5088501475 @default.
• W2013670462 hasConcept C104317684 @default.
• W2013670462 hasConcept C121608353 @default.
• W2013670462 hasConcept C126322002 @default.
• W2013670462 hasConcept C178790620 @default.
• W2013670462 hasConcept C185592680 @default.
• W2013670462 hasConcept C20719415 @default.
• W2013670462 hasConcept C2776438761 @default.
• W2013670462 hasConcept C2778128677 @default.
• W2013670462 hasConcept C2779723316 @default.
• W2013670462 hasConcept C502942594 @default.
• W2013670462 hasConcept C535196362 @default.
• W2013670462 hasConcept C54355233 @default.
• W2013670462 hasConcept C55493867 @default.
• W2013670462 hasConcept C71924100 @default.
• W2013670462 hasConcept C81885089 @default.
• W2013670462 hasConcept C86803240 @default.
• W2013670462 hasConcept C94581717 @default.
• W2013670462 hasConcept C96232424 @default.
• W2013670462 hasConceptScore W2013670462C104317684 @default.
• W2013670462 hasConceptScore W2013670462C121608353 @default.
• W2013670462 hasConceptScore W2013670462C126322002 @default.
• W2013670462 hasConceptScore W2013670462C178790620 @default.
• W2013670462 hasConceptScore W2013670462C185592680 @default.
• W2013670462 hasConceptScore W2013670462C20719415 @default.
• W2013670462 hasConceptScore W2013670462C2776438761 @default.
• W2013670462 hasConceptScore W2013670462C2778128677 @default.
• W2013670462 hasConceptScore W2013670462C2779723316 @default.
• W2013670462 hasConceptScore W2013670462C502942594 @default.
• W2013670462 hasConceptScore W2013670462C535196362 @default.
• W2013670462 hasConceptScore W2013670462C54355233 @default.
• W2013670462 hasConceptScore W2013670462C55493867 @default.
• W2013670462 hasConceptScore W2013670462C71924100 @default.
• W2013670462 hasConceptScore W2013670462C81885089 @default.
• W2013670462 hasConceptScore W2013670462C86803240 @default.
• W2013670462 hasConceptScore W2013670462C94581717 @default.
• W2013670462 hasConceptScore W2013670462C96232424 @default.
• W2013670462 hasFunder F4320320912 @default.
• W2013670462 hasIssue "4" @default.
• W2013670462 hasLocation W20136704621 @default.
• W2013670462 hasLocation W20136704622 @default.
• W2013670462 hasOpenAccess W2013670462 @default.
• W2013670462 hasPrimaryLocation W20136704621 @default.
• W2013670462 hasRelatedWork W2013670462 @default.
• W2013670462 hasRelatedWork W2018940456 @default.
• W2013670462 hasRelatedWork W2075512544 @default.
• W2013670462 hasRelatedWork W2321037413 @default.
• W2013670462 hasRelatedWork W2365426147 @default.
• W2013670462 hasRelatedWork W2378785636 @default.
• W2013670462 hasRelatedWork W3160990505 @default.

• next