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- W2013904816 abstract "Anemia (hematocrit less than 25%) predictably accompanies chronic renal failure and is present in over 90% of patients on chronic dialysis. Relative erythropoietin deficiency is the proximate cause. Recombinant human erythropoietin recently became available for research and clinical use. Erythropoietin production is regulated by a single copy gene located on chromosome 7; its expression has been shown in the kidney, liver, and macrophages. It is glycosylated protein of 166 amino acids with a molecular weight of 34,000 D. When given to patients with the anemia of renal failure, erythropoietin causes a dose-dependent rise in hematocrit to the normal range within 8 to 14 weeks. Complications of this response are minimal except for a significant incidence of hypertension. When the anemia is corrected, the patient's quality of life, cognitive function, and brain electrophysiology improve dramatically. Recombinant human erythropoietin represents a major breakthrough in the treatment of patients with chronic renal failure. Current reimbursement constraints limit its full application." @default.
- W2013904816 created "2016-06-24" @default.
- W2013904816 creator A5015456552 @default.
- W2013904816 creator A5020996374 @default.
- W2013904816 creator A5054286759 @default.
- W2013904816 date "1991-03-01" @default.
- W2013904816 modified "2023-10-07" @default.
- W2013904816 title "Recombinant Human Erythropoietin and Renal Anemia: Molecular Biology, Clinical Efficacy, and Nervous System Effects" @default.
- W2013904816 cites W1012979883 @default.
- W2013904816 cites W1486959216 @default.
- W2013904816 cites W1504261494 @default.
- W2013904816 cites W1508664328 @default.
- W2013904816 cites W1528664908 @default.
- W2013904816 cites W1541049769 @default.
- W2013904816 cites W1550363679 @default.
- W2013904816 cites W1551383822 @default.
- W2013904816 cites W1557267904 @default.
- W2013904816 cites W1565541955 @default.
- W2013904816 cites W1573656797 @default.
- W2013904816 cites W1582693243 @default.
- W2013904816 cites W1591586450 @default.
- W2013904816 cites W1595400617 @default.
- W2013904816 cites W1825344511 @default.
- W2013904816 cites W192971 @default.
- W2013904816 cites W1958193080 @default.
- W2013904816 cites W1959107903 @default.
- W2013904816 cites W1964576189 @default.
- W2013904816 cites W1964794067 @default.
- W2013904816 cites W1965574963 @default.
- W2013904816 cites W1966621021 @default.
- W2013904816 cites W1969291959 @default.
- W2013904816 cites W1969671700 @default.
- W2013904816 cites W1975862779 @default.
- W2013904816 cites W1978123270 @default.
- W2013904816 cites W1982012503 @default.
- W2013904816 cites W1983342381 @default.
- W2013904816 cites W1987189111 @default.
- W2013904816 cites W1990097831 @default.
- W2013904816 cites W1992573024 @default.
- W2013904816 cites W1994005628 @default.
- W2013904816 cites W1997031088 @default.
- W2013904816 cites W200215156 @default.
- W2013904816 cites W2002287505 @default.
- W2013904816 cites W2002792058 @default.
- W2013904816 cites W2004359917 @default.
- W2013904816 cites W2004650098 @default.
- W2013904816 cites W2004794137 @default.
- W2013904816 cites W2010256309 @default.
- W2013904816 cites W2015262361 @default.
- W2013904816 cites W2015691616 @default.
- W2013904816 cites W2016505924 @default.
- W2013904816 cites W2016846569 @default.
- W2013904816 cites W2017670274 @default.
- W2013904816 cites W2018552733 @default.
- W2013904816 cites W2019289959 @default.
- W2013904816 cites W2019368602 @default.
- W2013904816 cites W2022604215 @default.
- W2013904816 cites W2026452824 @default.
- W2013904816 cites W2029738096 @default.
- W2013904816 cites W2032997918 @default.
- W2013904816 cites W2036952926 @default.
- W2013904816 cites W2037641191 @default.
- W2013904816 cites W2038010401 @default.
- W2013904816 cites W2046121144 @default.
- W2013904816 cites W2046188084 @default.
- W2013904816 cites W2047747212 @default.
- W2013904816 cites W2048104971 @default.
- W2013904816 cites W2049363137 @default.
- W2013904816 cites W2055610997 @default.
- W2013904816 cites W2056635665 @default.
- W2013904816 cites W2056850109 @default.
- W2013904816 cites W2064830557 @default.
- W2013904816 cites W2065549220 @default.
- W2013904816 cites W2065577646 @default.
- W2013904816 cites W2065730723 @default.
- W2013904816 cites W2068908743 @default.
- W2013904816 cites W2072606606 @default.
- W2013904816 cites W2076354127 @default.
- W2013904816 cites W2077147171 @default.
- W2013904816 cites W2079302002 @default.
- W2013904816 cites W2080376404 @default.
- W2013904816 cites W2081413391 @default.
- W2013904816 cites W2082640992 @default.
- W2013904816 cites W2087529526 @default.
- W2013904816 cites W2088670766 @default.
- W2013904816 cites W2089874171 @default.
- W2013904816 cites W2093356536 @default.
- W2013904816 cites W2098538257 @default.
- W2013904816 cites W2110423779 @default.
- W2013904816 cites W2114497161 @default.
- W2013904816 cites W2127077870 @default.
- W2013904816 cites W2144795074 @default.
- W2013904816 cites W2152306961 @default.
- W2013904816 cites W2166156302 @default.
- W2013904816 cites W2167591049 @default.
- W2013904816 cites W2179643504 @default.
- W2013904816 cites W2196974557 @default.
- W2013904816 cites W2264254539 @default.