FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017041567> ?p ?o ?g. }

• W2017041567 endingPage "552" @default.
• W2017041567 startingPage "545" @default.
• W2017041567 abstract "The arrest sequence, FXXXXWIXXXXGIRAGP, of E. coli SecM interacts with the ribosomal exit tunnel, thereby interfering with translation elongation. Here, we studied this elongation arrest in vitro using purified translation components. While a simplest scenario would be that elongation is arrested beyond Pro166, the last arrest-essential amino acid, and that the Pro166 codon is positioned at the P site of the ribosomal peptidyl transferase center (PTC), our toeprint analyses revealed that the ribosome actually stalls when the Pro166 codon is positioned at the A site. Northern hybridization identification of the polypeptide bound tRNA and mass determination showed that the last amino acid of the arrested peptidyl-tRNA is Gly165, which is only inefficiently transferred to Pro166. Also, puromycin does not effectively release the arrested peptidyl-tRNA under the conditions of A site occupancy by Pro166-tRNA. These results reveal that secM-encoded Pro166-tRNA functions as a nonpolypeptide element in fulfilling SecM's role as a secretion monitor." @default.
• W2017041567 created "2016-06-24" @default.
• W2017041567 creator A5056272083 @default.
• W2017041567 creator A5057457862 @default.
• W2017041567 creator A5059902219 @default.
• W2017041567 date "2006-05-01" @default.
• W2017041567 modified "2023-10-16" @default.
• W2017041567 title "Genetically Encoded but Nonpolypeptide Prolyl-tRNA Functions in the A Site for SecM-Mediated Ribosomal Stall" @default.
• W2017041567 cites W1587481053 @default.
• W2017041567 cites W1628327926 @default.
• W2017041567 cites W1653006923 @default.
• W2017041567 cites W1972663311 @default.
• W2017041567 cites W1975255230 @default.
• W2017041567 cites W1975829385 @default.
• W2017041567 cites W1998234070 @default.
• W2017041567 cites W2001682416 @default.
• W2017041567 cites W2002031194 @default.
• W2017041567 cites W2013425130 @default.
• W2017041567 cites W2016978669 @default.
• W2017041567 cites W2020775118 @default.
• W2017041567 cites W2046938811 @default.
• W2017041567 cites W2072172236 @default.
• W2017041567 cites W2073149987 @default.
• W2017041567 cites W2078894416 @default.
• W2017041567 cites W2079081359 @default.
• W2017041567 cites W2094991732 @default.
• W2017041567 cites W2097654784 @default.
• W2017041567 cites W2099620187 @default.
• W2017041567 cites W2109086404 @default.
• W2017041567 cites W2111945100 @default.
• W2017041567 cites W2113338791 @default.
• W2017041567 cites W2122964499 @default.
• W2017041567 cites W2125865850 @default.
• W2017041567 cites W2129921323 @default.
• W2017041567 cites W2132839856 @default.
• W2017041567 cites W2145317409 @default.
• W2017041567 cites W2148198051 @default.
• W2017041567 cites W2150598386 @default.
• W2017041567 cites W2159648100 @default.
• W2017041567 cites W2168103157 @default.
• W2017041567 cites W4234308783 @default.
• W2017041567 doi "https://doi.org/10.1016/j.molcel.2006.03.033" @default.
• W2017041567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16713584" @default.
• W2017041567 hasPublicationYear "2006" @default.
• W2017041567 type Work @default.
• W2017041567 sameAs 2017041567 @default.
• W2017041567 citedByCount "135" @default.
• W2017041567 countsByYear W20170415672012 @default.
• W2017041567 countsByYear W20170415672013 @default.
• W2017041567 countsByYear W20170415672014 @default.
• W2017041567 countsByYear W20170415672015 @default.
• W2017041567 countsByYear W20170415672016 @default.
• W2017041567 countsByYear W20170415672017 @default.
• W2017041567 countsByYear W20170415672018 @default.
• W2017041567 countsByYear W20170415672019 @default.
• W2017041567 countsByYear W20170415672020 @default.
• W2017041567 countsByYear W20170415672021 @default.
• W2017041567 countsByYear W20170415672022 @default.
• W2017041567 countsByYear W20170415672023 @default.
• W2017041567 crossrefType "journal-article" @default.
• W2017041567 hasAuthorship W2017041567A5056272083 @default.
• W2017041567 hasAuthorship W2017041567A5057457862 @default.
• W2017041567 hasAuthorship W2017041567A5059902219 @default.
• W2017041567 hasBestOaLocation W20170415671 @default.
• W2017041567 hasConcept C104317684 @default.
• W2017041567 hasConcept C105580179 @default.
• W2017041567 hasConcept C106774688 @default.
• W2017041567 hasConcept C107824862 @default.
• W2017041567 hasConcept C149364088 @default.
• W2017041567 hasConcept C153957851 @default.
• W2017041567 hasConcept C2778321597 @default.
• W2017041567 hasConcept C2779200571 @default.
• W2017041567 hasConcept C3675279 @default.
• W2017041567 hasConcept C515207424 @default.
• W2017041567 hasConcept C55493867 @default.
• W2017041567 hasConcept C67705224 @default.
• W2017041567 hasConcept C67905577 @default.
• W2017041567 hasConcept C86803240 @default.
• W2017041567 hasConcept C88478588 @default.
• W2017041567 hasConcept C95444343 @default.
• W2017041567 hasConcept C96267730 @default.
• W2017041567 hasConceptScore W2017041567C104317684 @default.
• W2017041567 hasConceptScore W2017041567C105580179 @default.
• W2017041567 hasConceptScore W2017041567C106774688 @default.
• W2017041567 hasConceptScore W2017041567C107824862 @default.
• W2017041567 hasConceptScore W2017041567C149364088 @default.
• W2017041567 hasConceptScore W2017041567C153957851 @default.
• W2017041567 hasConceptScore W2017041567C2778321597 @default.
• W2017041567 hasConceptScore W2017041567C2779200571 @default.
• W2017041567 hasConceptScore W2017041567C3675279 @default.
• W2017041567 hasConceptScore W2017041567C515207424 @default.
• W2017041567 hasConceptScore W2017041567C55493867 @default.
• W2017041567 hasConceptScore W2017041567C67705224 @default.
• W2017041567 hasConceptScore W2017041567C67905577 @default.
• W2017041567 hasConceptScore W2017041567C86803240 @default.
• W2017041567 hasConceptScore W2017041567C88478588 @default.
• W2017041567 hasConceptScore W2017041567C95444343 @default.
• W2017041567 hasConceptScore W2017041567C96267730 @default.

• next