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- W2017402835 abstract "DNA repair in eukaryotic cells takes place in the context of chromatin, where DNA, including damaged DNA, is tightly packed into nucleosomes and higher order chromatin structures. Chromatin intrinsically restricts accessibility of DNA repair proteins to the damaged DNA and impacts upon the overall rate of DNA repair. Chromatin is highly responsive to DNA damage and undergoes specific remodeling to facilitate DNA repair. How damaged DNA is accessed, repaired and restored to the original chromatin state, and how chromatin remodeling coordinates these processes in vivo, remains largely unknown. ATP-dependent chromatin remodelers (ACRs) are the master regulators of chromatin structure and dynamics. Conserved from yeast to humans, ACRs utilize the energy of ATP to reorganize packing of chromatin and control DNA accessibility by sliding, ejecting or restructuring nucleosomes. Several studies have demonstrated that ATP-dependent remodeling activity of ACRs plays important roles in coordination of spatio-temporal steps of different DNA repair pathways in chromatin. This review focuses on the role of ACRs in regulation of various aspects of nucleotide excision repair (NER) in the context of chromatin. We discuss current understanding of ATP-dependent chromatin remodeling by various subfamilies of remodelers and regulation of the NER pathway in vivo." @default.
- W2017402835 created "2016-06-24" @default.
- W2017402835 creator A5023748043 @default.
- W2017402835 creator A5064038738 @default.
- W2017402835 creator A5080261955 @default.
- W2017402835 date "2012-09-20" @default.
- W2017402835 modified "2023-10-08" @default.
- W2017402835 title "The Emerging Roles of ATP-Dependent Chromatin Remodeling Enzymes in Nucleotide Excision Repair" @default.
- W2017402835 cites W1520588455 @default.
- W2017402835 cites W1534917150 @default.
- W2017402835 cites W1554069754 @default.
- W2017402835 cites W1598637952 @default.
- W2017402835 cites W1620981049 @default.
- W2017402835 cites W1625510017 @default.
- W2017402835 cites W1816804869 @default.
- W2017402835 cites W1964922169 @default.
- W2017402835 cites W1969934670 @default.
- W2017402835 cites W1971517620 @default.
- W2017402835 cites W1974426680 @default.
- W2017402835 cites W1974795717 @default.
- W2017402835 cites W1976945603 @default.
- W2017402835 cites W1979123830 @default.
- W2017402835 cites W1979540894 @default.
- W2017402835 cites W1980887180 @default.
- W2017402835 cites W1981010319 @default.
- W2017402835 cites W1981033633 @default.
- W2017402835 cites W1981045115 @default.
- W2017402835 cites W1983137562 @default.
- W2017402835 cites W1984328011 @default.
- W2017402835 cites W1988756461 @default.
- W2017402835 cites W1989325752 @default.
- W2017402835 cites W1989968124 @default.
- W2017402835 cites W1990586926 @default.
- W2017402835 cites W1990717903 @default.
- W2017402835 cites W1992167329 @default.
- W2017402835 cites W1993138135 @default.
- W2017402835 cites W1993142537 @default.
- W2017402835 cites W1995586000 @default.
- W2017402835 cites W1996516839 @default.
- W2017402835 cites W2004891581 @default.
- W2017402835 cites W2005725366 @default.
- W2017402835 cites W2007986017 @default.
- W2017402835 cites W2008185037 @default.
- W2017402835 cites W2009536322 @default.
- W2017402835 cites W2013947447 @default.
- W2017402835 cites W2015725762 @default.
- W2017402835 cites W2016589736 @default.
- W2017402835 cites W2019025864 @default.
- W2017402835 cites W2020084014 @default.
- W2017402835 cites W2020582422 @default.
- W2017402835 cites W2022093187 @default.
- W2017402835 cites W2022558320 @default.
- W2017402835 cites W2028604413 @default.
- W2017402835 cites W2030748126 @default.
- W2017402835 cites W2032471242 @default.
- W2017402835 cites W2034195501 @default.
- W2017402835 cites W2036477200 @default.
- W2017402835 cites W2037485742 @default.
- W2017402835 cites W2039502138 @default.
- W2017402835 cites W2041090138 @default.
- W2017402835 cites W2041742383 @default.
- W2017402835 cites W2041803958 @default.
- W2017402835 cites W2044143247 @default.
- W2017402835 cites W2044904363 @default.
- W2017402835 cites W2046079276 @default.
- W2017402835 cites W2046082575 @default.
- W2017402835 cites W2047384517 @default.
- W2017402835 cites W2050664073 @default.
- W2017402835 cites W2052978365 @default.
- W2017402835 cites W2054864177 @default.
- W2017402835 cites W2056826119 @default.
- W2017402835 cites W2057475298 @default.
- W2017402835 cites W2057663036 @default.
- W2017402835 cites W2060289784 @default.
- W2017402835 cites W2061111901 @default.
- W2017402835 cites W2061505893 @default.
- W2017402835 cites W2062057606 @default.
- W2017402835 cites W2068640920 @default.
- W2017402835 cites W2069237225 @default.
- W2017402835 cites W2069328568 @default.
- W2017402835 cites W2070582215 @default.
- W2017402835 cites W2074536099 @default.
- W2017402835 cites W2074597022 @default.
- W2017402835 cites W2075662557 @default.
- W2017402835 cites W2082425829 @default.
- W2017402835 cites W2082960726 @default.
- W2017402835 cites W2084908485 @default.
- W2017402835 cites W2088703460 @default.
- W2017402835 cites W2089243923 @default.
- W2017402835 cites W2092104135 @default.
- W2017402835 cites W2092797711 @default.
- W2017402835 cites W2092937197 @default.
- W2017402835 cites W2094592924 @default.
- W2017402835 cites W2096136751 @default.
- W2017402835 cites W2097309081 @default.
- W2017402835 cites W2098387013 @default.
- W2017402835 cites W2102273403 @default.
- W2017402835 cites W2102604046 @default.