Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023952282> ?p ?o ?g. }
- W2023952282 endingPage "27" @default.
- W2023952282 startingPage "20" @default.
- W2023952282 abstract "Objective: To assess serious gastroenteritis risk and mortality associated with early cessation of breastfeeding in infants enrolled in 2 prevention of maternal-to-child HIV-transmission trials in Uganda.Methods: We used hazard rates to evaluate serious gastroenteritis events by month of age and mortality among HIV-exposed uninfected infants enrolled in the HIV Network for Prevention Trials (HIVNET 012) (1997–2001) and HIV hyperimmune globulin (HIVIGLOB)/nevirapine (NVP) (2004–2007) trials. HIV-infected mothers were counseled using local infant feeding guidelines current at the time.Results: Breastfeeding cessation occurred earlier in HIVIGLOB/NVP compared with HIVNET 012 (median 4.0 versus 9.3 months,P,0.001). Rates of serious gastroenteritis were higher in HIVIGLOB/NVP (8.0/1000 child-months) than in HIVNET 012 (3.1/1000 child-months; P , 0.001). Serious gastroenteritis events also peaked earlier at 3–4 and 7–8 months (16.2/1000 and 15.0/1000 child-months,respectively) compared with HIVNET 012 at 9–10 months (20.8/1000 child-months). All cause infant mortality did not statistically differ between the HIVIGLOB/NVP and the HIVNET 012 trials [3.2/1000 versus 2.0/1000 child-months, respectively (P = 0.10)].Conclusions: Early breastfeeding cessation seen in the HIVIGLOB/NVP trial was associated with increased risk of serious gastroenteritis among HIV-exposed uninfected infants when compared with later breastfeeding cessation in the HIVNET 012 trial.Testing interventions, which could decrease HIV transmission through breastfeeding and allow safe" @default.
- W2023952282 created "2016-06-24" @default.
- W2023952282 creator A5000033990 @default.
- W2023952282 creator A5009085628 @default.
- W2023952282 creator A5010396412 @default.
- W2023952282 creator A5016065942 @default.
- W2023952282 creator A5034556592 @default.
- W2023952282 creator A5040800904 @default.
- W2023952282 creator A5050624256 @default.
- W2023952282 creator A5057946567 @default.
- W2023952282 creator A5065239950 @default.
- W2023952282 creator A5072063401 @default.
- W2023952282 creator A5076002328 @default.
- W2023952282 creator A5088626365 @default.
- W2023952282 date "2010-01-01" @default.
- W2023952282 modified "2023-09-30" @default.
- W2023952282 title "Early Weaning of HIV-Exposed Uninfected Infants and Risk of Serious Gastroenteritis: Findings from Two Perinatal HIV Prevention Trials in Kampala, Uganda" @default.
- W2023952282 cites W1576975323 @default.
- W2023952282 cites W1983196576 @default.
- W2023952282 cites W1990105675 @default.
- W2023952282 cites W1991071311 @default.
- W2023952282 cites W1993806523 @default.
- W2023952282 cites W2016788712 @default.
- W2023952282 cites W2038183880 @default.
- W2023952282 cites W2054292852 @default.
- W2023952282 cites W2068506384 @default.
- W2023952282 cites W2074960015 @default.
- W2023952282 cites W2090568674 @default.
- W2023952282 cites W2124039449 @default.
- W2023952282 cites W2130271632 @default.
- W2023952282 cites W2134206097 @default.
- W2023952282 cites W2142788507 @default.
- W2023952282 cites W2154053721 @default.
- W2023952282 cites W2157994668 @default.
- W2023952282 cites W2159324987 @default.
- W2023952282 cites W2164723930 @default.
- W2023952282 cites W2165657851 @default.
- W2023952282 cites W2170947401 @default.
- W2023952282 cites W4233178319 @default.
- W2023952282 cites W4245348407 @default.
- W2023952282 doi "https://doi.org/10.1097/qai.0b013e3181bdf68e" @default.
- W2023952282 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2888913" @default.
- W2023952282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19779355" @default.
- W2023952282 hasPublicationYear "2010" @default.
- W2023952282 type Work @default.
- W2023952282 sameAs 2023952282 @default.
- W2023952282 citedByCount "62" @default.
- W2023952282 countsByYear W20239522822012 @default.
- W2023952282 countsByYear W20239522822013 @default.
- W2023952282 countsByYear W20239522822014 @default.
- W2023952282 countsByYear W20239522822015 @default.
- W2023952282 countsByYear W20239522822016 @default.
- W2023952282 countsByYear W20239522822017 @default.
- W2023952282 countsByYear W20239522822018 @default.
- W2023952282 countsByYear W20239522822019 @default.
- W2023952282 countsByYear W20239522822022 @default.
- W2023952282 countsByYear W20239522822023 @default.
- W2023952282 crossrefType "journal-article" @default.
- W2023952282 hasAuthorship W2023952282A5000033990 @default.
- W2023952282 hasAuthorship W2023952282A5009085628 @default.
- W2023952282 hasAuthorship W2023952282A5010396412 @default.
- W2023952282 hasAuthorship W2023952282A5016065942 @default.
- W2023952282 hasAuthorship W2023952282A5034556592 @default.
- W2023952282 hasAuthorship W2023952282A5040800904 @default.
- W2023952282 hasAuthorship W2023952282A5050624256 @default.
- W2023952282 hasAuthorship W2023952282A5057946567 @default.
- W2023952282 hasAuthorship W2023952282A5065239950 @default.
- W2023952282 hasAuthorship W2023952282A5072063401 @default.
- W2023952282 hasAuthorship W2023952282A5076002328 @default.
- W2023952282 hasAuthorship W2023952282A5088626365 @default.
- W2023952282 hasBestOaLocation W20239522821 @default.
- W2023952282 hasConcept C118552586 @default.
- W2023952282 hasConcept C131872663 @default.
- W2023952282 hasConcept C142462285 @default.
- W2023952282 hasConcept C187212893 @default.
- W2023952282 hasConcept C203014093 @default.
- W2023952282 hasConcept C27415008 @default.
- W2023952282 hasConcept C2776283161 @default.
- W2023952282 hasConcept C2779130552 @default.
- W2023952282 hasConcept C2993143319 @default.
- W2023952282 hasConcept C3013748606 @default.
- W2023952282 hasConcept C3020294031 @default.
- W2023952282 hasConcept C71924100 @default.
- W2023952282 hasConceptScore W2023952282C118552586 @default.
- W2023952282 hasConceptScore W2023952282C131872663 @default.
- W2023952282 hasConceptScore W2023952282C142462285 @default.
- W2023952282 hasConceptScore W2023952282C187212893 @default.
- W2023952282 hasConceptScore W2023952282C203014093 @default.
- W2023952282 hasConceptScore W2023952282C27415008 @default.
- W2023952282 hasConceptScore W2023952282C2776283161 @default.
- W2023952282 hasConceptScore W2023952282C2779130552 @default.
- W2023952282 hasConceptScore W2023952282C2993143319 @default.
- W2023952282 hasConceptScore W2023952282C3013748606 @default.
- W2023952282 hasConceptScore W2023952282C3020294031 @default.
- W2023952282 hasConceptScore W2023952282C71924100 @default.
- W2023952282 hasIssue "1" @default.
- W2023952282 hasLocation W20239522821 @default.
- W2023952282 hasLocation W20239522822 @default.