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- W2024032511 abstract "Abstract Co-infections by multiple pathogen strains are common in the wild. Theory predicts co-infections to have major consequences for both within- and between-host disease dynamics, but data are currently scarce. Here, using common garden populations of Plantago lanceolata infected by two strains of the pathogen Podosphaera plantaginis , either singly or under co-infection, we find the highest disease prevalence in co-infected treatments both at the host genotype and population levels. A spore-trapping experiment demonstrates that co-infected hosts shed more transmission propagules than singly infected hosts, thereby explaining the observed change in epidemiological dynamics. Our experimental findings are confirmed in natural pathogen populations—more devastating epidemics were measured in populations with higher levels of co-infection. Jointly, our results confirm the predictions made by theoretical and experimental studies for the potential of co-infection to alter disease dynamics across a large host–pathogen metapopulation." @default.
- W2024032511 created "2016-06-24" @default.
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- W2024032511 date "2015-01-08" @default.
- W2024032511 modified "2023-10-17" @default.
- W2024032511 title "Co-infection alters population dynamics of infectious disease" @default.
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- W2024032511 doi "https://doi.org/10.1038/ncomms6975" @default.
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