FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024373359> ?p ?o ?g. }

• W2024373359 endingPage "2154" @default.
• W2024373359 startingPage "2147" @default.
• W2024373359 abstract "BACKGROUND: Among the well described cytogenetic abnormalities in adults with acute lymphoblastic leukemia (ALL), a translocation involving chromosomes 1 and 19 (t[1;19] [q23;p13]) occurs in a small subset but has been associated variously with an intermediate prognosis or a bad prognosis in different studies. METHODS: Adults with ALL and t(1;19) who were treated at The University of Texas M. D. Anderson Cancer Center were reviewed. Their clinical features and outcomes were compared with those of patients who had other cytogenetic abnormalities. The study endpoints included the complete remission (CR) rate, the complete response duration (CRD), and overall survival (OS). RESULTS: Of 411 adults with pre-B-cell ALL, 12 patients had t(1;19). Ten of 12 patients with t(1;19) received hyperfractionated cyclophosphamide, vincristine, doxorubicin (Adriamycin), and dexamethasone alternating with methotrexate and high-dose cytarabine (hyper-CVAD) chemotherapy; and the other 2 patients received combined vincristine, doxorubicin, and dexamethasone (VAD). All 12 patients achieved CR, and the 3-year survival rate was 73%. Patients with t(1;19) had significantly better CRD and OS compared with all other patients combined and compared individually with patients who had Philadelphia chromosome-positive, t(4;11), and lymphoma-like abnormalities (deletion 6q, addition q14q, t[11;14], and t[14;18]). CONCLUSIONS: Adults with ALL and t(1;19) had an excellent prognosis when the received the hyper-CVAD regimen. Cancer 2009. © 2009 American Cancer Society." @default.
• W2024373359 created "2016-06-24" @default.
• W2024373359 creator A5000750846 @default.
• W2024373359 creator A5006104041 @default.
• W2024373359 creator A5018615127 @default.
• W2024373359 creator A5030500582 @default.
• W2024373359 creator A5031294439 @default.
• W2024373359 creator A5038307470 @default.
• W2024373359 creator A5046097970 @default.
• W2024373359 creator A5090435894 @default.
• W2024373359 date "2009-03-19" @default.
• W2024373359 modified "2023-10-12" @default.
• W2024373359 title "Adults with acute lymphoblastic leukemia and translocation (1;19) abnormality have a favorable outcome with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with methotrexate and high-dose cytarabine chemotherapy" @default.
• W2024373359 cites W138639959 @default.
• W2024373359 cites W1587946844 @default.
• W2024373359 cites W182243169 @default.
• W2024373359 cites W1834314364 @default.
• W2024373359 cites W1862517694 @default.
• W2024373359 cites W1884891985 @default.
• W2024373359 cites W1977380325 @default.
• W2024373359 cites W1986288031 @default.
• W2024373359 cites W2004153775 @default.
• W2024373359 cites W2012188343 @default.
• W2024373359 cites W2063898537 @default.
• W2024373359 cites W2092925278 @default.
• W2024373359 cites W2113594413 @default.
• W2024373359 cites W2125486570 @default.
• W2024373359 cites W2128491464 @default.
• W2024373359 cites W2209081858 @default.
• W2024373359 cites W225957511 @default.
• W2024373359 cites W2330004714 @default.
• W2024373359 cites W2336990540 @default.
• W2024373359 cites W2440705721 @default.
• W2024373359 cites W4239897690 @default.
• W2024373359 cites W4293241248 @default.
• W2024373359 cites W89089254 @default.
• W2024373359 doi "https://doi.org/10.1002/cncr.24266" @default.
• W2024373359 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4199455" @default.
• W2024373359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19298009" @default.
• W2024373359 hasPublicationYear "2009" @default.
• W2024373359 type Work @default.
• W2024373359 sameAs 2024373359 @default.
• W2024373359 citedByCount "26" @default.
• W2024373359 countsByYear W20243733592013 @default.
• W2024373359 countsByYear W20243733592014 @default.
• W2024373359 countsByYear W20243733592015 @default.
• W2024373359 countsByYear W20243733592016 @default.
• W2024373359 countsByYear W20243733592017 @default.
• W2024373359 countsByYear W20243733592019 @default.
• W2024373359 countsByYear W20243733592020 @default.
• W2024373359 countsByYear W20243733592021 @default.
• W2024373359 countsByYear W20243733592023 @default.
• W2024373359 crossrefType "journal-article" @default.
• W2024373359 hasAuthorship W2024373359A5000750846 @default.
• W2024373359 hasAuthorship W2024373359A5006104041 @default.
• W2024373359 hasAuthorship W2024373359A5018615127 @default.
• W2024373359 hasAuthorship W2024373359A5030500582 @default.
• W2024373359 hasAuthorship W2024373359A5031294439 @default.
• W2024373359 hasAuthorship W2024373359A5038307470 @default.
• W2024373359 hasAuthorship W2024373359A5046097970 @default.
• W2024373359 hasAuthorship W2024373359A5090435894 @default.
• W2024373359 hasBestOaLocation W20243733592 @default.
• W2024373359 hasConcept C121608353 @default.
• W2024373359 hasConcept C126322002 @default.
• W2024373359 hasConcept C143998085 @default.
• W2024373359 hasConcept C2776694085 @default.
• W2024373359 hasConcept C2776755627 @default.
• W2024373359 hasConcept C2778041864 @default.
• W2024373359 hasConcept C2778461978 @default.
• W2024373359 hasConcept C2779429289 @default.
• W2024373359 hasConcept C2780401358 @default.
• W2024373359 hasConcept C2781107101 @default.
• W2024373359 hasConcept C2781413609 @default.
• W2024373359 hasConcept C2909962599 @default.
• W2024373359 hasConcept C71924100 @default.
• W2024373359 hasConcept C90924648 @default.
• W2024373359 hasConceptScore W2024373359C121608353 @default.
• W2024373359 hasConceptScore W2024373359C126322002 @default.
• W2024373359 hasConceptScore W2024373359C143998085 @default.
• W2024373359 hasConceptScore W2024373359C2776694085 @default.
• W2024373359 hasConceptScore W2024373359C2776755627 @default.
• W2024373359 hasConceptScore W2024373359C2778041864 @default.
• W2024373359 hasConceptScore W2024373359C2778461978 @default.
• W2024373359 hasConceptScore W2024373359C2779429289 @default.
• W2024373359 hasConceptScore W2024373359C2780401358 @default.
• W2024373359 hasConceptScore W2024373359C2781107101 @default.
• W2024373359 hasConceptScore W2024373359C2781413609 @default.
• W2024373359 hasConceptScore W2024373359C2909962599 @default.
• W2024373359 hasConceptScore W2024373359C71924100 @default.
• W2024373359 hasConceptScore W2024373359C90924648 @default.
• W2024373359 hasIssue "10" @default.
• W2024373359 hasLocation W20243733591 @default.
• W2024373359 hasLocation W20243733592 @default.
• W2024373359 hasLocation W20243733593 @default.
• W2024373359 hasLocation W20243733594 @default.
• W2024373359 hasOpenAccess W2024373359 @default.
• W2024373359 hasPrimaryLocation W20243733591 @default.
• W2024373359 hasRelatedWork W1978070076 @default.

• next