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• W2025428992 startingPage "78" @default.
• W2025428992 abstract "Trout normally spawn at 3 years of age, however, a small percentage mature a year early. This provides an opportunity to study reproductive timing and developmental processes. The ovarian and testicular extracellular matrix (ECM) participates in processes such as growth, adhesion, differentiation, cell migration and patterning. The composition of the ECM defines the interactions of specific regulatory ligands with their receptors and modulates and regulates gonadal function. To identify some of the genes involved in these processes, a 16,006-gene salmonid cDNA microarray was used to compare three-year-old normal with two-year-old normal (maturing) and with two-year-old precocious (pre-spawn) ovarian and testicular transcriptomes. We provide evidence for differences in expression of some of the genes during vasculogenesis, angiogenesis, fibrillogenesis and other processes involving ECM remodeling. Sex-specific gene expression differences of ECM components were documented between the trout ovary and testis in each developmental state. Significant differences in the expression of genes involved in translation, transcription, cell-cycling and differentiation were identified. We also report, for the first time, unequivocal evidence for the transcription of high levels of adult and embryonic hemoglobins in the developed ovary; and for the expression of transcripts that encode zona pellucida glycoproteins in both the ovary and testis of trout." @default.
• W2025428992 created "2016-06-24" @default.
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• W2025428992 date "2008-03-01" @default.
• W2025428992 modified "2023-09-27" @default.
• W2025428992 title "Microarray analysis reveals differences in expression of cell surface and extracellular matrix components during development of the trout ovary and testis" @default.
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• W2025428992 doi "https://doi.org/10.1016/j.cbd.2007.10.001" @default.
• W2025428992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20483209" @default.
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