FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025589177> ?p ?o ?g. }

• W2025589177 endingPage "96" @default.
• W2025589177 startingPage "96e" @default.
• W2025589177 abstract "Reconstruction of haplotypes, or the allelic phase, of single nucleotide polymorphisms (SNPs) is a key component of studies aimed at the identification and dissection of genetic factors involved in complex genetic traits. In humans, this often involves investigation of SNPs in case/control or other cohorts in which the haplotypes can only be partially inferred from genotypes by statistical approaches with resulting loss of power. Moreover, alternative statistical methodologies can lead to different evaluations of the most probable haplotypes present, and different haplotype frequency estimates when data are ambiguous. Given the cost and complexity of SNP studies, a robust and easy‐to‐use molecular technique that allows haplotypes to be determined directly from individual DNA samples would have wide applicability. Here, we present a reliable, automated and high‐throughput method for molecular haplotyping in 2 kb, and potentially longer, sequence segments that is based on the physical determination of the phase of SNP alleles on either of the individual paternal haploids. We demonstrate that molecular haplotyping with this technique is not more complicated than SNP genotyping when implemented by matrix‐assisted laser desorption/ionisation mass spectrometry, and we also show that the method can be applied using other DNA variation detection platforms. Molecular haplotyping is illustrated on the well‐described β 2 ‐adrenergic receptor gene." @default.
• W2025589177 created "2016-06-24" @default.
• W2025589177 creator A5071537878 @default.
• W2025589177 date "2002-10-01" @default.
• W2025589177 modified "2023-09-25" @default.
• W2025589177 title "Molecular haplotyping at high throughput" @default.
• W2025589177 cites W12411709 @default.
• W2025589177 cites W1511393905 @default.
• W2025589177 cites W1542543893 @default.
• W2025589177 cites W1589411629 @default.
• W2025589177 cites W1965278426 @default.
• W2025589177 cites W1968435166 @default.
• W2025589177 cites W1974830441 @default.
• W2025589177 cites W1979388953 @default.
• W2025589177 cites W1988602365 @default.
• W2025589177 cites W1990343281 @default.
• W2025589177 cites W2005187240 @default.
• W2025589177 cites W2014611019 @default.
• W2025589177 cites W2015879776 @default.
• W2025589177 cites W2021290807 @default.
• W2025589177 cites W2025306791 @default.
• W2025589177 cites W2036032782 @default.
• W2025589177 cites W2051930377 @default.
• W2025589177 cites W2059297225 @default.
• W2025589177 cites W2059693046 @default.
• W2025589177 cites W2061008984 @default.
• W2025589177 cites W2064063117 @default.
• W2025589177 cites W2064991824 @default.
• W2025589177 cites W2072134379 @default.
• W2025589177 cites W2074820933 @default.
• W2025589177 cites W2082863489 @default.
• W2025589177 cites W2114525046 @default.
• W2025589177 cites W2124277514 @default.
• W2025589177 cites W2127162896 @default.
• W2025589177 cites W2144858697 @default.
• W2025589177 cites W2150943442 @default.
• W2025589177 cites W2152664025 @default.
• W2025589177 cites W2159108856 @default.
• W2025589177 cites W2159901647 @default.
• W2025589177 cites W2164795026 @default.
• W2025589177 cites W2299998870 @default.
• W2025589177 cites W2328233417 @default.
• W2025589177 cites W2400094570 @default.
• W2025589177 cites W2416342525 @default.
• W2025589177 cites W2775744576 @default.
• W2025589177 doi "https://doi.org/10.1093/nar/gnf095" @default.
• W2025589177 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/140556" @default.
• W2025589177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12364613" @default.
• W2025589177 hasPublicationYear "2002" @default.
• W2025589177 type Work @default.
• W2025589177 sameAs 2025589177 @default.
• W2025589177 citedByCount "47" @default.
• W2025589177 countsByYear W20255891772012 @default.
• W2025589177 countsByYear W20255891772013 @default.
• W2025589177 countsByYear W20255891772015 @default.
• W2025589177 crossrefType "journal-article" @default.
• W2025589177 hasAuthorship W2025589177A5071537878 @default.
• W2025589177 hasBestOaLocation W20255891772 @default.
• W2025589177 hasConcept C104317684 @default.
• W2025589177 hasConcept C135763542 @default.
• W2025589177 hasConcept C139275648 @default.
• W2025589177 hasConcept C153209595 @default.
• W2025589177 hasConcept C163691529 @default.
• W2025589177 hasConcept C180754005 @default.
• W2025589177 hasConcept C197754878 @default.
• W2025589177 hasConcept C31467283 @default.
• W2025589177 hasConcept C44432683 @default.
• W2025589177 hasConcept C54355233 @default.
• W2025589177 hasConcept C70721500 @default.
• W2025589177 hasConcept C86803240 @default.
• W2025589177 hasConceptScore W2025589177C104317684 @default.
• W2025589177 hasConceptScore W2025589177C135763542 @default.
• W2025589177 hasConceptScore W2025589177C139275648 @default.
• W2025589177 hasConceptScore W2025589177C153209595 @default.
• W2025589177 hasConceptScore W2025589177C163691529 @default.
• W2025589177 hasConceptScore W2025589177C180754005 @default.
• W2025589177 hasConceptScore W2025589177C197754878 @default.
• W2025589177 hasConceptScore W2025589177C31467283 @default.
• W2025589177 hasConceptScore W2025589177C44432683 @default.
• W2025589177 hasConceptScore W2025589177C54355233 @default.
• W2025589177 hasConceptScore W2025589177C70721500 @default.
• W2025589177 hasConceptScore W2025589177C86803240 @default.
• W2025589177 hasIssue "19" @default.
• W2025589177 hasLocation W20255891771 @default.
• W2025589177 hasLocation W20255891772 @default.
• W2025589177 hasLocation W20255891773 @default.
• W2025589177 hasLocation W20255891774 @default.
• W2025589177 hasLocation W20255891775 @default.
• W2025589177 hasOpenAccess W2025589177 @default.
• W2025589177 hasPrimaryLocation W20255891771 @default.
• W2025589177 hasRelatedWork W1504890006 @default.
• W2025589177 hasRelatedWork W1508523048 @default.
• W2025589177 hasRelatedWork W1966708416 @default.
• W2025589177 hasRelatedWork W2071146638 @default.
• W2025589177 hasRelatedWork W2164332050 @default.
• W2025589177 hasRelatedWork W2184363627 @default.
• W2025589177 hasRelatedWork W2283861756 @default.
• W2025589177 hasRelatedWork W2329658823 @default.

• next