FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025804561> ?p ?o ?g. }

• W2025804561 endingPage "e1002877" @default.
• W2025804561 startingPage "e1002877" @default.
• W2025804561 abstract "Statistical imputation of classical HLA alleles in case-control studies has become established as a valuable tool for identifying and fine-mapping signals of disease association in the MHC. Imputation into diverse populations has, however, remained challenging, mainly because of the additional haplotypic heterogeneity introduced by combining reference panels of different sources. We present an HLA type imputation model, HLA*IMP:02, designed to operate on a multi-population reference panel. HLA*IMP:02 is based on a graphical representation of haplotype structure. We present a probabilistic algorithm to build such models for the HLA region, accommodating genotyping error, haplotypic heterogeneity and the need for maximum accuracy at the HLA loci, generalizing the work of Browning and Browning (2007) and Ron et al. (1998). HLA*IMP:02 achieves an average 4-digit imputation accuracy on diverse European panels of 97% (call rate 97%). On non-European samples, 2-digit performance is over 90% for most loci and ethnicities where data available. HLA*IMP:02 supports imputation of HLA-DPB1 and HLA-DRB3-5, is highly tolerant of missing data in the imputation panel and works on standard genotype data from popular genotyping chips. It is publicly available in source code and as a user-friendly web service framework." @default.
• W2025804561 created "2016-06-24" @default.
• W2025804561 creator A5000481707 @default.
• W2025804561 creator A5051336451 @default.
• W2025804561 creator A5055377368 @default.
• W2025804561 creator A5057439502 @default.
• W2025804561 creator A5061035699 @default.
• W2025804561 creator A5084707794 @default.
• W2025804561 creator A5085839256 @default.
• W2025804561 date "2013-02-14" @default.
• W2025804561 modified "2023-10-12" @default.
• W2025804561 title "Multi-Population Classical HLA Type Imputation" @default.
• W2025804561 cites W1962960380 @default.
• W2025804561 cites W1964759280 @default.
• W2025804561 cites W1966026613 @default.
• W2025804561 cites W1992085420 @default.
• W2025804561 cites W2000186602 @default.
• W2025804561 cites W2016370312 @default.
• W2025804561 cites W2026884584 @default.
• W2025804561 cites W2027688494 @default.
• W2025804561 cites W2036626452 @default.
• W2025804561 cites W2040547343 @default.
• W2025804561 cites W2059251603 @default.
• W2025804561 cites W2087036932 @default.
• W2025804561 cites W2109130469 @default.
• W2025804561 cites W2111307685 @default.
• W2025804561 cites W2119279196 @default.
• W2025804561 cites W2133148918 @default.
• W2025804561 cites W2138345444 @default.
• W2025804561 cites W2149791927 @default.
• W2025804561 cites W2152381343 @default.
• W2025804561 cites W2156459362 @default.
• W2025804561 cites W2156719275 @default.
• W2025804561 cites W2157752701 @default.
• W2025804561 cites W2161098179 @default.
• W2025804561 cites W2161633633 @default.
• W2025804561 cites W3089948396 @default.
• W2025804561 cites W4240204556 @default.
• W2025804561 doi "https://doi.org/10.1371/journal.pcbi.1002877" @default.
• W2025804561 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3572961" @default.
• W2025804561 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23459081" @default.
• W2025804561 hasPublicationYear "2013" @default.
• W2025804561 type Work @default.
• W2025804561 sameAs 2025804561 @default.
• W2025804561 citedByCount "155" @default.
• W2025804561 countsByYear W20258045612013 @default.
• W2025804561 countsByYear W20258045612014 @default.
• W2025804561 countsByYear W20258045612015 @default.
• W2025804561 countsByYear W20258045612016 @default.
• W2025804561 countsByYear W20258045612017 @default.
• W2025804561 countsByYear W20258045612018 @default.
• W2025804561 countsByYear W20258045612019 @default.
• W2025804561 countsByYear W20258045612020 @default.
• W2025804561 countsByYear W20258045612021 @default.
• W2025804561 countsByYear W20258045612022 @default.
• W2025804561 countsByYear W20258045612023 @default.
• W2025804561 crossrefType "journal-article" @default.
• W2025804561 hasAuthorship W2025804561A5000481707 @default.
• W2025804561 hasAuthorship W2025804561A5051336451 @default.
• W2025804561 hasAuthorship W2025804561A5055377368 @default.
• W2025804561 hasAuthorship W2025804561A5057439502 @default.
• W2025804561 hasAuthorship W2025804561A5061035699 @default.
• W2025804561 hasAuthorship W2025804561A5084707794 @default.
• W2025804561 hasAuthorship W2025804561A5085839256 @default.
• W2025804561 hasBestOaLocation W20258045611 @default.
• W2025804561 hasConcept C104317684 @default.
• W2025804561 hasConcept C119857082 @default.
• W2025804561 hasConcept C135763542 @default.
• W2025804561 hasConcept C147483822 @default.
• W2025804561 hasConcept C188280979 @default.
• W2025804561 hasConcept C197754878 @default.
• W2025804561 hasConcept C2908647359 @default.
• W2025804561 hasConcept C31467283 @default.
• W2025804561 hasConcept C41008148 @default.
• W2025804561 hasConcept C54355233 @default.
• W2025804561 hasConcept C58041806 @default.
• W2025804561 hasConcept C71924100 @default.
• W2025804561 hasConcept C86803240 @default.
• W2025804561 hasConcept C9357733 @default.
• W2025804561 hasConcept C99454951 @default.
• W2025804561 hasConceptScore W2025804561C104317684 @default.
• W2025804561 hasConceptScore W2025804561C119857082 @default.
• W2025804561 hasConceptScore W2025804561C135763542 @default.
• W2025804561 hasConceptScore W2025804561C147483822 @default.
• W2025804561 hasConceptScore W2025804561C188280979 @default.
• W2025804561 hasConceptScore W2025804561C197754878 @default.
• W2025804561 hasConceptScore W2025804561C2908647359 @default.
• W2025804561 hasConceptScore W2025804561C31467283 @default.
• W2025804561 hasConceptScore W2025804561C41008148 @default.
• W2025804561 hasConceptScore W2025804561C54355233 @default.
• W2025804561 hasConceptScore W2025804561C58041806 @default.
• W2025804561 hasConceptScore W2025804561C71924100 @default.
• W2025804561 hasConceptScore W2025804561C86803240 @default.
• W2025804561 hasConceptScore W2025804561C9357733 @default.
• W2025804561 hasConceptScore W2025804561C99454951 @default.
• W2025804561 hasIssue "2" @default.
• W2025804561 hasLocation W20258045611 @default.
• W2025804561 hasLocation W20258045612 @default.

• next