FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029490660> ?p ?o ?g. }

• W2029490660 abstract "The extent of coupling between the folding of a protein and its binding to a substrate varies from protein to protein. Some proteins have highly structured native states in solution, while others are natively disordered and only fold fully upon binding. In this Letter, we use Monte Carlo simulations to investigate how disordered polymer chains grafted around a binding site affect the folding and binding of three model proteins. The protein that approaches the substrate fully folded is more hindered during the binding process than those whose folding and binding are cooperative. The polymer chains act as localized crowding agents and can select correctly folded and bound configurations in favor of nonspecifically adsorbed states. The free energy change for forming all intraprotein and protein-substrate contacts can depend nonmonotonically on the polymer length." @default.
• W2029490660 created "2016-06-24" @default.
• W2029490660 creator A5017691760 @default.
• W2029490660 creator A5026141543 @default.
• W2029490660 creator A5036947439 @default.
• W2029490660 date "2012-05-15" @default.
• W2029490660 modified "2023-10-17" @default.
• W2029490660 title "Controlling the Folding and Substrate-Binding of Proteins Using Polymer Brushes" @default.
• W2029490660 cites W1610965833 @default.
• W2029490660 cites W1975017420 @default.
• W2029490660 cites W1977334225 @default.
• W2029490660 cites W1982610162 @default.
• W2029490660 cites W2001079236 @default.
• W2029490660 cites W2003670327 @default.
• W2029490660 cites W2011475679 @default.
• W2029490660 cites W2017150085 @default.
• W2029490660 cites W2044730187 @default.
• W2029490660 cites W2049889518 @default.
• W2029490660 cites W2051489942 @default.
• W2029490660 cites W2061040254 @default.
• W2029490660 cites W2073745520 @default.
• W2029490660 cites W2076223139 @default.
• W2029490660 cites W2078167403 @default.
• W2029490660 cites W2098208486 @default.
• W2029490660 cites W2108651330 @default.
• W2029490660 cites W2108709048 @default.
• W2029490660 cites W2124920204 @default.
• W2029490660 cites W2146895524 @default.
• W2029490660 cites W2170948389 @default.
• W2029490660 doi "https://doi.org/10.1103/physrevlett.108.208104" @default.
• W2029490660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23003194" @default.
• W2029490660 hasPublicationYear "2012" @default.
• W2029490660 type Work @default.
• W2029490660 sameAs 2029490660 @default.
• W2029490660 citedByCount "15" @default.
• W2029490660 countsByYear W20294906602012 @default.
• W2029490660 countsByYear W20294906602013 @default.
• W2029490660 countsByYear W20294906602014 @default.
• W2029490660 countsByYear W20294906602016 @default.
• W2029490660 countsByYear W20294906602017 @default.
• W2029490660 countsByYear W20294906602018 @default.
• W2029490660 countsByYear W20294906602022 @default.
• W2029490660 crossrefType "journal-article" @default.
• W2029490660 hasAuthorship W2029490660A5017691760 @default.
• W2029490660 hasAuthorship W2029490660A5026141543 @default.
• W2029490660 hasAuthorship W2029490660A5036947439 @default.
• W2029490660 hasBestOaLocation W20294906602 @default.
• W2029490660 hasConcept C107824862 @default.
• W2029490660 hasConcept C119599485 @default.
• W2029490660 hasConcept C121332964 @default.
• W2029490660 hasConcept C12554922 @default.
• W2029490660 hasConcept C127413603 @default.
• W2029490660 hasConcept C159467904 @default.
• W2029490660 hasConcept C159985019 @default.
• W2029490660 hasConcept C181990884 @default.
• W2029490660 hasConcept C185544564 @default.
• W2029490660 hasConcept C185592680 @default.
• W2029490660 hasConcept C18903297 @default.
• W2029490660 hasConcept C192562407 @default.
• W2029490660 hasConcept C204328495 @default.
• W2029490660 hasConcept C204389451 @default.
• W2029490660 hasConcept C2776545253 @default.
• W2029490660 hasConcept C2777289219 @default.
• W2029490660 hasConcept C32598905 @default.
• W2029490660 hasConcept C51639874 @default.
• W2029490660 hasConcept C521977710 @default.
• W2029490660 hasConcept C55493867 @default.
• W2029490660 hasConcept C8010536 @default.
• W2029490660 hasConcept C86803240 @default.
• W2029490660 hasConcept C93282013 @default.
• W2029490660 hasConceptScore W2029490660C107824862 @default.
• W2029490660 hasConceptScore W2029490660C119599485 @default.
• W2029490660 hasConceptScore W2029490660C121332964 @default.
• W2029490660 hasConceptScore W2029490660C12554922 @default.
• W2029490660 hasConceptScore W2029490660C127413603 @default.
• W2029490660 hasConceptScore W2029490660C159467904 @default.
• W2029490660 hasConceptScore W2029490660C159985019 @default.
• W2029490660 hasConceptScore W2029490660C181990884 @default.
• W2029490660 hasConceptScore W2029490660C185544564 @default.
• W2029490660 hasConceptScore W2029490660C185592680 @default.
• W2029490660 hasConceptScore W2029490660C18903297 @default.
• W2029490660 hasConceptScore W2029490660C192562407 @default.
• W2029490660 hasConceptScore W2029490660C204328495 @default.
• W2029490660 hasConceptScore W2029490660C204389451 @default.
• W2029490660 hasConceptScore W2029490660C2776545253 @default.
• W2029490660 hasConceptScore W2029490660C2777289219 @default.
• W2029490660 hasConceptScore W2029490660C32598905 @default.
• W2029490660 hasConceptScore W2029490660C51639874 @default.
• W2029490660 hasConceptScore W2029490660C521977710 @default.
• W2029490660 hasConceptScore W2029490660C55493867 @default.
• W2029490660 hasConceptScore W2029490660C8010536 @default.
• W2029490660 hasConceptScore W2029490660C86803240 @default.
• W2029490660 hasConceptScore W2029490660C93282013 @default.
• W2029490660 hasIssue "20" @default.
• W2029490660 hasLocation W20294906601 @default.
• W2029490660 hasLocation W20294906602 @default.
• W2029490660 hasLocation W20294906603 @default.
• W2029490660 hasOpenAccess W2029490660 @default.
• W2029490660 hasPrimaryLocation W20294906601 @default.
• W2029490660 hasRelatedWork W1971087828 @default.

• next