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• W2029695719 endingPage "10" @default.
• W2029695719 startingPage "3" @default.
• W2029695719 abstract "The classic view that the role of immune cells in cancer is primarily one of tumor rejection has been supplanted by a more complex view of leukocytes having both pro- and anti-tumor properties. This shift is due to the now well recognized capabilities of several myeloid cell types that foster pro-tumor programming of premalignant tissue, as well as the discovery that subsets of leukocytes also suppress development and effector functions of lymphocytes important for mediating anti-tumor immunity. In this review, we focus on the underappreciated role that T lymphocytes play in promoting tumor development. This includes, in addition to the role of T regulatory cells, a role for natural killer T cells and CD4+ T helper cells in suppressing anti-tumor immunity and promoting cancer growth and metastasis." @default.
• W2029695719 created "2016-06-24" @default.
• W2029695719 creator A5021009961 @default.
• W2029695719 creator A5021307040 @default.
• W2029695719 creator A5025353193 @default.
• W2029695719 creator A5066901504 @default.
• W2029695719 date "2010-02-01" @default.
• W2029695719 modified "2023-09-27" @default.
• W2029695719 title "Lymphocytes in cancer development: Polarization towards pro-tumor immunity" @default.
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