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- W2030908087 abstract "Abstract The synthesis and conformational analysis of a “bridged” anabasine, 5,8,9,10,11,11a-hexahydro-6H-pyrido[2,1-f][1,6] naphthyridine ( 5 ), and related compounds are reported. Conformational assignments were made using NMR data (including coupling constants, homonuclear Overhauser effects, and 2D correlations) and the results of molecular mechanics (MM2) calculations. The tricyclic compounds have trans-quinolizidine ring fusion with a chair-shaped piperidine ring. The center ring shows a half-chair conformation for the title compound, and a half-boat shape for its 6-oxo derivative. Calculated vicinal coupling constants are in good agreement with those obtained experimentally." @default.
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- W2030908087 date "1994-01-01" @default.
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- W2030908087 title "Synthesis and conformational analysis of a bridged anabasine and related compounds. A nuclear magnetic resonance spectroscopy and molecular modeling study." @default.
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- W2030908087 doi "https://doi.org/10.1016/s0040-4020(01)89606-x" @default.
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