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• W2041505280 abstract "Nucleotide-binding proteins are often used as molecular switches to control the assembly or activity of macromolecular machines. Recent work has revealed that such molecular switches also regulate the spread of some mobile DNA elements. Bacteriophage Mu and the bacterial transposon Tn7 each use an ATP-dependent molecular switch to select a new site for insertion and to coordinate the assembly of the transposition machinery at that site. Strong parallels between these ATP-dependent transposition proteins and other well-characterized molecular switches, such as Ras and EF-Tu, have emerged." @default.
• W2041505280 created "2016-06-24" @default.
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• W2041505280 creator A5072606581 @default.
• W2041505280 date "1998-12-01" @default.
• W2041505280 modified "2023-09-25" @default.
• W2041505280 title "Mobile DNA elements: controlling transposition with ATP-dependent molecular switches" @default.
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• W2041505280 doi "https://doi.org/10.1016/s0968-0004(98)01325-5" @default.
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