FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041783371> ?p ?o ?g. }

• W2041783371 endingPage "208" @default.
• W2041783371 startingPage "203" @default.
• W2041783371 abstract "Conclusion: Focal adhesion kinase (FAK) and integrin-linked kinase (ILK) are highly expressed in salivary adenoid cystic carcinoma (SACC), especially metastatic SACC, suggesting their potential role as prognostic markers for SACC. Objectives: This study aimed to investigate the expression of FAK, ILK, and phosphatase and tensin homolog deleted on chromosome ten (PTEN) in SACC tissues and the clinical significance. Methods: PAK and ILK expression in samples from 50 cases of SACC and 12 subjects with normal salivary glands was detected by immunohistochemical analysis. PAK and ILK expression in SACC cell lines was detected by RT-PCR and Western blot analysis. Results: The positive rate of PAK and ILK staining was 94% (47/50) and 48% (24/50) in SACC, respectively, significantly higher than in normal salivary gland tissues (p < 0.05). However, the positive rate of PTEN staining was 30% (15/50), significantly lower than in normal salivary gland tissues (p < 0.05). Pearson analysis showed that FAK expression was positively correlated with ILK expression but negatively correlated with PTEN expression in SACC tissues. FAK and ILK expression was positively associated with advanced stage, solid histological subtype, perineural invasion, and distant metastasis of SACC (p < 0.05). In addition, FAK and ILK expression at both mRNA and protein levels was significantly higher in highly metastatic SACC-LM cells than low-metastatic SACC-83 cells." @default.
• W2041783371 created "2016-06-24" @default.
• W2041783371 creator A5005658067 @default.
• W2041783371 creator A5021273421 @default.
• W2041783371 creator A5036566027 @default.
• W2041783371 creator A5046881277 @default.
• W2041783371 creator A5054037070 @default.
• W2041783371 creator A5077157954 @default.
• W2041783371 date "2012-11-27" @default.
• W2041783371 modified "2023-10-16" @default.
• W2041783371 title "Expression and clinical significance of FAK, ILK, and PTEN in salivary adenoid cystic carcinoma" @default.
• W2041783371 cites W1964006565 @default.
• W2041783371 cites W1964376417 @default.
• W2041783371 cites W1967279903 @default.
• W2041783371 cites W1970923523 @default.
• W2041783371 cites W1985401645 @default.
• W2041783371 cites W1992716524 @default.
• W2041783371 cites W2018056622 @default.
• W2041783371 cites W2023575363 @default.
• W2041783371 cites W2047288783 @default.
• W2041783371 cites W2065593072 @default.
• W2041783371 cites W2086270282 @default.
• W2041783371 cites W2086703438 @default.
• W2041783371 cites W2087472895 @default.
• W2041783371 cites W2123573124 @default.
• W2041783371 cites W2132678065 @default.
• W2041783371 doi "https://doi.org/10.3109/00016489.2012.728295" @default.
• W2041783371 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23186335" @default.
• W2041783371 hasPublicationYear "2012" @default.
• W2041783371 type Work @default.
• W2041783371 sameAs 2041783371 @default.
• W2041783371 citedByCount "7" @default.
• W2041783371 countsByYear W20417833712013 @default.
• W2041783371 countsByYear W20417833712017 @default.
• W2041783371 countsByYear W20417833712018 @default.
• W2041783371 countsByYear W20417833712021 @default.
• W2041783371 crossrefType "journal-article" @default.
• W2041783371 hasAuthorship W2041783371A5005658067 @default.
• W2041783371 hasAuthorship W2041783371A5021273421 @default.
• W2041783371 hasAuthorship W2041783371A5036566027 @default.
• W2041783371 hasAuthorship W2041783371A5046881277 @default.
• W2041783371 hasAuthorship W2041783371A5054037070 @default.
• W2041783371 hasAuthorship W2041783371A5077157954 @default.
• W2041783371 hasConcept C104317684 @default.
• W2041783371 hasConcept C121608353 @default.
• W2041783371 hasConcept C142724271 @default.
• W2041783371 hasConcept C1491633281 @default.
• W2041783371 hasConcept C151166631 @default.
• W2041783371 hasConcept C204232928 @default.
• W2041783371 hasConcept C2776415932 @default.
• W2041783371 hasConcept C2777154038 @default.
• W2041783371 hasConcept C2777546739 @default.
• W2041783371 hasConcept C2777609662 @default.
• W2041783371 hasConcept C2778937882 @default.
• W2041783371 hasConcept C2779013556 @default.
• W2041783371 hasConcept C2779231225 @default.
• W2041783371 hasConcept C2779549131 @default.
• W2041783371 hasConcept C29537977 @default.
• W2041783371 hasConcept C502942594 @default.
• W2041783371 hasConcept C54355233 @default.
• W2041783371 hasConcept C55493867 @default.
• W2041783371 hasConcept C62478195 @default.
• W2041783371 hasConcept C66417403 @default.
• W2041783371 hasConcept C71924100 @default.
• W2041783371 hasConcept C82495950 @default.
• W2041783371 hasConcept C86554907 @default.
• W2041783371 hasConcept C86803240 @default.
• W2041783371 hasConcept C95444343 @default.
• W2041783371 hasConceptScore W2041783371C104317684 @default.
• W2041783371 hasConceptScore W2041783371C121608353 @default.
• W2041783371 hasConceptScore W2041783371C142724271 @default.
• W2041783371 hasConceptScore W2041783371C1491633281 @default.
• W2041783371 hasConceptScore W2041783371C151166631 @default.
• W2041783371 hasConceptScore W2041783371C204232928 @default.
• W2041783371 hasConceptScore W2041783371C2776415932 @default.
• W2041783371 hasConceptScore W2041783371C2777154038 @default.
• W2041783371 hasConceptScore W2041783371C2777546739 @default.
• W2041783371 hasConceptScore W2041783371C2777609662 @default.
• W2041783371 hasConceptScore W2041783371C2778937882 @default.
• W2041783371 hasConceptScore W2041783371C2779013556 @default.
• W2041783371 hasConceptScore W2041783371C2779231225 @default.
• W2041783371 hasConceptScore W2041783371C2779549131 @default.
• W2041783371 hasConceptScore W2041783371C29537977 @default.
• W2041783371 hasConceptScore W2041783371C502942594 @default.
• W2041783371 hasConceptScore W2041783371C54355233 @default.
• W2041783371 hasConceptScore W2041783371C55493867 @default.
• W2041783371 hasConceptScore W2041783371C62478195 @default.
• W2041783371 hasConceptScore W2041783371C66417403 @default.
• W2041783371 hasConceptScore W2041783371C71924100 @default.
• W2041783371 hasConceptScore W2041783371C82495950 @default.
• W2041783371 hasConceptScore W2041783371C86554907 @default.
• W2041783371 hasConceptScore W2041783371C86803240 @default.
• W2041783371 hasConceptScore W2041783371C95444343 @default.
• W2041783371 hasIssue "2" @default.
• W2041783371 hasLocation W20417833711 @default.
• W2041783371 hasLocation W20417833712 @default.
• W2041783371 hasOpenAccess W2041783371 @default.
• W2041783371 hasPrimaryLocation W20417833711 @default.

• next