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• W2044596784 abstract "During nucleocapsid assembly, filamentous actin (F-actin) colocalizes with the major capsid protein of Autographa californica M nucleopolyhedrovirus (AcMNPV) within nuclei of infected lepidopteran host cells. Cytochalasin D (CD) disrupts actin filaments and prevents assembly of progeny AcMNPV, suggesting that nuclear F-actin is essential for nucleocapsid morphogenesis. Direct proof for this hypothesis was provided by the demonstration that two AcMNPV recombinants engineered to express either wild-type- or CD-resistant actin at equivalent rates were differentially sensitive to CD. The AcMNPV requirement for nuclear F-actin is unique among intracellular pathogens and may constitute a significant host range factor." @default.
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• W2044596784 date "1999-11-01" @default.
• W2044596784 modified "2023-09-24" @default.
• W2044596784 title "Nuclear F-Actin Is Required for AcMNPV Nucleocapsid Morphogenesis" @default.
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• W2044596784 doi "https://doi.org/10.1006/viro.1999.0008" @default.
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