FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047003783> ?p ?o ?g. }

• W2047003783 endingPage "162" @default.
• W2047003783 startingPage "162" @default.
• W2047003783 abstract "Nowadays, owing to medicinal plants as a candidate to obtain promising new medicinal agents, there is a renewed interest in the use of these natural sources for drug development.In the present study, we aimed to assess the anticholinesterase, antioxidant, and neuropotective effects of Tripleurospermum disciforme and Dracocephalum multicaule extracts.Methanolic extract of the plants was prepared by maceration method. Anticholinesterase effect of different concentrations of the plants was studied by colorimetric method and antioxidant activity was evaluated using diphenypicrylhydrazil (DPPH) assay. Protective effect of the extracts against amyloid β (Aβ)-induced toxicity in PC12 cells was determined by MTT (3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide) method.Both T. disciforme and D. multicaule extracts could inhibit acetylcholinesterase (AChE) in a dose-dependent manner. The highest inhibition occurred at 5 μg/ml (71.18 ± 4.9 and 79.06 ± 3.1% inhibition respectively by T. disciforme and D. multicaule) in comparison to tacrine (86.37 ± 3.24%). The greatest DPPH inhibition of T. disciforme and D. multicaule was shown at 800 μg/ml (89.04 ± 3.9 and 78.5 ± 3.7%, respectively). None of tested extracts induced protection against βA toxicity in PC12 cell.Although the results indicated anticholinesterase and antioxidant of the T. disciforme and D. multicaule, further specific studies and scientific validity are needed." @default.
• W2047003783 created "2016-06-24" @default.
• W2047003783 creator A5025776260 @default.
• W2047003783 creator A5032943371 @default.
• W2047003783 creator A5051087709 @default.
• W2047003783 creator A5086713841 @default.
• W2047003783 date "2014-01-01" @default.
• W2047003783 modified "2023-09-30" @default.
• W2047003783 title "Anticholinesterase, antioxidant, and neuroprotective effects of Tripleurospermum disciforme and Dracocephalum multicaule" @default.
• W2047003783 cites W1671272116 @default.
• W2047003783 cites W1908615065 @default.
• W2047003783 cites W1946984015 @default.
• W2047003783 cites W1967372871 @default.
• W2047003783 cites W1983176088 @default.
• W2047003783 cites W1988158524 @default.
• W2047003783 cites W1989621439 @default.
• W2047003783 cites W1996259742 @default.
• W2047003783 cites W2013914182 @default.
• W2047003783 cites W2017327362 @default.
• W2047003783 cites W2022997414 @default.
• W2047003783 cites W2043757245 @default.
• W2047003783 cites W2061664301 @default.
• W2047003783 cites W2065446982 @default.
• W2047003783 cites W2068318042 @default.
• W2047003783 cites W2071364419 @default.
• W2047003783 cites W2080653789 @default.
• W2047003783 cites W2086245670 @default.
• W2047003783 cites W2091141988 @default.
• W2047003783 cites W2093984890 @default.
• W2047003783 cites W2099253787 @default.
• W2047003783 cites W2117790528 @default.
• W2047003783 cites W2131569086 @default.
• W2047003783 cites W2137777161 @default.
• W2047003783 cites W2163663214 @default.
• W2047003783 cites W2282423478 @default.
• W2047003783 cites W2302860725 @default.
• W2047003783 doi "https://doi.org/10.4103/0975-9476.140474" @default.
• W2047003783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4204286" @default.
• W2047003783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25336847" @default.
• W2047003783 hasPublicationYear "2014" @default.
• W2047003783 type Work @default.
• W2047003783 sameAs 2047003783 @default.
• W2047003783 citedByCount "15" @default.
• W2047003783 countsByYear W20470037832016 @default.
• W2047003783 countsByYear W20470037832018 @default.
• W2047003783 countsByYear W20470037832019 @default.
• W2047003783 countsByYear W20470037832020 @default.
• W2047003783 countsByYear W20470037832022 @default.
• W2047003783 countsByYear W20470037832023 @default.
• W2047003783 crossrefType "journal-article" @default.
• W2047003783 hasAuthorship W2047003783A5025776260 @default.
• W2047003783 hasAuthorship W2047003783A5032943371 @default.
• W2047003783 hasAuthorship W2047003783A5051087709 @default.
• W2047003783 hasAuthorship W2047003783A5086713841 @default.
• W2047003783 hasBestOaLocation W20470037833 @default.
• W2047003783 hasConcept C159985019 @default.
• W2047003783 hasConcept C178790620 @default.
• W2047003783 hasConcept C181199279 @default.
• W2047003783 hasConcept C185592680 @default.
• W2047003783 hasConcept C192562407 @default.
• W2047003783 hasConcept C2778004101 @default.
• W2047003783 hasConcept C2778816929 @default.
• W2047003783 hasConcept C2779046751 @default.
• W2047003783 hasConcept C2779059548 @default.
• W2047003783 hasConcept C2781401929 @default.
• W2047003783 hasConcept C29730261 @default.
• W2047003783 hasConcept C55493867 @default.
• W2047003783 hasConcept C556039675 @default.
• W2047003783 hasConcept C71924100 @default.
• W2047003783 hasConcept C74940592 @default.
• W2047003783 hasConcept C86803240 @default.
• W2047003783 hasConcept C98274493 @default.
• W2047003783 hasConceptScore W2047003783C159985019 @default.
• W2047003783 hasConceptScore W2047003783C178790620 @default.
• W2047003783 hasConceptScore W2047003783C181199279 @default.
• W2047003783 hasConceptScore W2047003783C185592680 @default.
• W2047003783 hasConceptScore W2047003783C192562407 @default.
• W2047003783 hasConceptScore W2047003783C2778004101 @default.
• W2047003783 hasConceptScore W2047003783C2778816929 @default.
• W2047003783 hasConceptScore W2047003783C2779046751 @default.
• W2047003783 hasConceptScore W2047003783C2779059548 @default.
• W2047003783 hasConceptScore W2047003783C2781401929 @default.
• W2047003783 hasConceptScore W2047003783C29730261 @default.
• W2047003783 hasConceptScore W2047003783C55493867 @default.
• W2047003783 hasConceptScore W2047003783C556039675 @default.
• W2047003783 hasConceptScore W2047003783C71924100 @default.
• W2047003783 hasConceptScore W2047003783C74940592 @default.
• W2047003783 hasConceptScore W2047003783C86803240 @default.
• W2047003783 hasConceptScore W2047003783C98274493 @default.
• W2047003783 hasIssue "3" @default.
• W2047003783 hasLocation W20470037831 @default.
• W2047003783 hasLocation W20470037832 @default.
• W2047003783 hasLocation W20470037833 @default.
• W2047003783 hasLocation W20470037834 @default.
• W2047003783 hasLocation W20470037835 @default.
• W2047003783 hasOpenAccess W2047003783 @default.
• W2047003783 hasPrimaryLocation W20470037831 @default.
• W2047003783 hasRelatedWork W1973449292 @default.

• next