FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051214913> ?p ?o ?g. }

• W2051214913 endingPage "339" @default.
• W2051214913 startingPage "334" @default.
• W2051214913 abstract "Objective: Prokinetic medications are used in premature infants to promote motility and decrease time to full enteral feeding. Erythromycin and metoclopramide are the most commonly used prokinetic medications in the neonatal intensive care unit (NICU), but their safety profile is not well defined. Methods: We conducted a large retrospective cohort study using data from 348 NICUs managed by the Pediatrix Medical Group. All of the infants exposed to ≥1 dose of erythromycin, metoclopramide, or both, from a cohort of 8,87,910 infants discharged between 1997 and 2012 were included. We collected laboratory and clinical information while infants were exposed to erythromycin or metoclopramide and described the frequency of laboratory abnormalities and clinical adverse events (AEs). Results: Metoclopramide use increased from 1997 to 2005 and decreased from 2005 to 2012, whereas erythromycin use remained stable. Erythromycin use was most often associated with a diagnosis of feeding problem (40%), whereas metoclopramide was most often associated with a diagnosis of gastroesophageal reflux (59%). The most common laboratory AE during exposure to erythromycin or metoclopramide was hyperkalemia (8.6/1000 infant days on erythromycin and 11.0/1000 infant days on metoclopramide). Incidence of pyloric stenosis was greater with erythromycin than with metoclopramide (10/1095, 0.9% vs 76/19,001, 0.4%; P = 0.01), but odds were not significantly increased after adjusting for covariates (odds ratio 0.52, 95% confidence interval [CI] 0.26–1.02, P = 0.06). More infants experienced an AE while treated with metoclopramide than with erythromycin (odds ratio 1.21, 95% CI 1.03–1.43). Conclusions: Metoclopramide was associated with increased risk of AEs compared with erythromycin. Studies are needed to confirm safety and effectiveness of both the drugs in infants." @default.
• W2051214913 created "2016-06-24" @default.
• W2051214913 creator A5008393749 @default.
• W2051214913 creator A5008852386 @default.
• W2051214913 creator A5011072724 @default.
• W2051214913 creator A5017862279 @default.
• W2051214913 creator A5044647951 @default.
• W2051214913 creator A5060263635 @default.
• W2051214913 creator A5068911315 @default.
• W2051214913 creator A5070669648 @default.
• W2051214913 creator A5076556014 @default.
• W2051214913 creator A5081987147 @default.
• W2051214913 creator A5085031950 @default.
• W2051214913 date "2015-09-01" @default.
• W2051214913 modified "2023-10-01" @default.
• W2051214913 title "Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants" @default.
• W2051214913 cites W122720305 @default.
• W2051214913 cites W1966361081 @default.
• W2051214913 cites W1982573419 @default.
• W2051214913 cites W1996161723 @default.
• W2051214913 cites W1996639676 @default.
• W2051214913 cites W2000708217 @default.
• W2051214913 cites W2015573228 @default.
• W2051214913 cites W2024873539 @default.
• W2051214913 cites W2029094948 @default.
• W2051214913 cites W2029918158 @default.
• W2051214913 cites W20302444 @default.
• W2051214913 cites W2032055439 @default.
• W2051214913 cites W2033829367 @default.
• W2051214913 cites W2042890431 @default.
• W2051214913 cites W2044674651 @default.
• W2051214913 cites W2046728250 @default.
• W2051214913 cites W2061200444 @default.
• W2051214913 cites W2062426892 @default.
• W2051214913 cites W2063122799 @default.
• W2051214913 cites W2066998519 @default.
• W2051214913 cites W2074111290 @default.
• W2051214913 cites W2086657271 @default.
• W2051214913 cites W2088246083 @default.
• W2051214913 cites W2093534950 @default.
• W2051214913 cites W2094915638 @default.
• W2051214913 cites W2109712738 @default.
• W2051214913 cites W2116418340 @default.
• W2051214913 cites W2128367633 @default.
• W2051214913 cites W2133356829 @default.
• W2051214913 cites W2144319263 @default.
• W2051214913 cites W2155957464 @default.
• W2051214913 cites W2182760264 @default.
• W2051214913 cites W2298145239 @default.
• W2051214913 cites W2330223296 @default.
• W2051214913 cites W2398644742 @default.
• W2051214913 cites W4235817932 @default.
• W2051214913 cites W8942200 @default.
• W2051214913 cites W91386120 @default.
• W2051214913 doi "https://doi.org/10.1097/mpg.0000000000000792" @default.
• W2051214913 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4553109" @default.
• W2051214913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25806675" @default.
• W2051214913 hasPublicationYear "2015" @default.
• W2051214913 type Work @default.
• W2051214913 sameAs 2051214913 @default.
• W2051214913 citedByCount "26" @default.
• W2051214913 countsByYear W20512149132016 @default.
• W2051214913 countsByYear W20512149132018 @default.
• W2051214913 countsByYear W20512149132019 @default.
• W2051214913 countsByYear W20512149132020 @default.
• W2051214913 countsByYear W20512149132021 @default.
• W2051214913 countsByYear W20512149132022 @default.
• W2051214913 countsByYear W20512149132023 @default.
• W2051214913 crossrefType "journal-article" @default.
• W2051214913 hasAuthorship W2051214913A5008393749 @default.
• W2051214913 hasAuthorship W2051214913A5008852386 @default.
• W2051214913 hasAuthorship W2051214913A5011072724 @default.
• W2051214913 hasAuthorship W2051214913A5017862279 @default.
• W2051214913 hasAuthorship W2051214913A5044647951 @default.
• W2051214913 hasAuthorship W2051214913A5060263635 @default.
• W2051214913 hasAuthorship W2051214913A5068911315 @default.
• W2051214913 hasAuthorship W2051214913A5070669648 @default.
• W2051214913 hasAuthorship W2051214913A5076556014 @default.
• W2051214913 hasAuthorship W2051214913A5081987147 @default.
• W2051214913 hasAuthorship W2051214913A5085031950 @default.
• W2051214913 hasBestOaLocation W20512149132 @default.
• W2051214913 hasConcept C126322002 @default.
• W2051214913 hasConcept C156957248 @default.
• W2051214913 hasConcept C187212893 @default.
• W2051214913 hasConcept C197934379 @default.
• W2051214913 hasConcept C2777091541 @default.
• W2051214913 hasConcept C2778479196 @default.
• W2051214913 hasConcept C2780206985 @default.
• W2051214913 hasConcept C2780852908 @default.
• W2051214913 hasConcept C42219234 @default.
• W2051214913 hasConcept C501593827 @default.
• W2051214913 hasConcept C71924100 @default.
• W2051214913 hasConcept C86803240 @default.
• W2051214913 hasConcept C89423630 @default.
• W2051214913 hasConceptScore W2051214913C126322002 @default.
• W2051214913 hasConceptScore W2051214913C156957248 @default.
• W2051214913 hasConceptScore W2051214913C187212893 @default.
• W2051214913 hasConceptScore W2051214913C197934379 @default.

• next