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• W2054242592 abstract "This study was designed to determine the behavioral effects of a reduction in catecholamine and indoleamine function in healthy subjects. Eight healthy subjects received the tyrosine hydroxylase inhibitor, alpha-methyl-para-tyrosine (AMPT) in combination with a full-strength tryptophan-depleting amino acid drink during one 4-day test session, and AMPT and tryptophan-supplemented amino acid drink (n = 2), or a 25% strength tryptophan-depleting amino acid drink (n = 6) during a second 4-day test session. The combined administration of AMPT and the tryptophan-free amino acid drink did not produce statistically significant or even clinically noticeable changes in mood among the healthy subjects. The implications of these observations for the monoamine hypotheses of depression are discussed." @default.
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• W2054242592 date "1997-01-01" @default.
• W2054242592 modified "2023-09-23" @default.
• W2054242592 title "Lack of behavioral effects of monoamine depletion in healthy subjects" @default.
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• W2054242592 doi "https://doi.org/10.1016/0006-3223(95)00670-2" @default.
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