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- W2055103624 abstract "High-functioning individuals with autism have been found to favor visuospatial processing in the face of typically poor language abilities. We aimed to examine the neurobiological basis of this difference using functional magnetic resonance imaging and diffusion tensor imaging. We compared 12 children with high functioning autism (HFA) to 12 age- and IQ-matched typically developing controls (CTRL) on a pictorial reasoning paradigm under three conditions: V, requiring visuospatial processing; S, requiring language (i.e., semantic) processing; and V+S, a hybrid condition in which language use could facilitate visuospatial transformations. Activated areas in the brain were chosen as endpoints for probabilistic diffusion tractography to examine tract integrity (FA) within the structural network underlying the activation patterns. The two groups showed similar networks, with linguistic processing activating inferior frontal, superior and middle temporal, ventral visual, and temporo-parietal areas, whereas visuospatial processing activated occipital and inferior parietal cortices. However, HFA appeared to activate occipito-parietal and ventral temporal areas, whereas CTRL relied more on frontal and temporal language regions. The increased reliance on visuospatial abilities in HFA was supported by intact connections between the inferior parietal and the ventral temporal ROIs. In contrast, the inferior frontal region showed reduced connectivity to ventral temporal and middle temporal areas in this group, reflecting impaired activation of frontal language areas in autism. The HFA group's engagement of posterior brain regions along with its weak connections to frontal language areas suggest support for a reliance on visual mediation in autism, even in tasks of higher cognition." @default.
- W2055103624 created "2016-06-24" @default.
- W2055103624 creator A5006602535 @default.
- W2055103624 creator A5019877004 @default.
- W2055103624 creator A5029778876 @default.
- W2055103624 creator A5073290912 @default.
- W2055103624 creator A5075647759 @default.
- W2055103624 date "2010-01-01" @default.
- W2055103624 modified "2023-10-14" @default.
- W2055103624 title "Neuroimaging of the functional and structural networks underlying visuospatial vs. linguistic reasoning in high-functioning autism" @default.
- W2055103624 cites W1552608186 @default.
- W2055103624 cites W1652226287 @default.
- W2055103624 cites W1964802316 @default.
- W2055103624 cites W1967597672 @default.
- W2055103624 cites W1970339525 @default.
- W2055103624 cites W1973759448 @default.
- W2055103624 cites W1980309199 @default.
- W2055103624 cites W1983752817 @default.
- W2055103624 cites W1986603538 @default.
- W2055103624 cites W1995486390 @default.
- W2055103624 cites W1998463996 @default.
- W2055103624 cites W2004293194 @default.
- W2055103624 cites W2006096283 @default.
- W2055103624 cites W2008069933 @default.
- W2055103624 cites W2012410262 @default.
- W2055103624 cites W2018445037 @default.
- W2055103624 cites W2020272960 @default.
- W2055103624 cites W2021243932 @default.
- W2055103624 cites W2023886727 @default.
- W2055103624 cites W2026452816 @default.
- W2055103624 cites W2029355232 @default.
- W2055103624 cites W2031012798 @default.
- W2055103624 cites W2037581000 @default.
- W2055103624 cites W2043428207 @default.
- W2055103624 cites W2043524544 @default.
- W2055103624 cites W2045960328 @default.
- W2055103624 cites W2047711471 @default.
- W2055103624 cites W2048911223 @default.
- W2055103624 cites W2050321595 @default.
- W2055103624 cites W2052419000 @default.
- W2055103624 cites W2052934262 @default.
- W2055103624 cites W2054875016 @default.
- W2055103624 cites W2055866745 @default.
- W2055103624 cites W2056397825 @default.
- W2055103624 cites W2062178487 @default.
- W2055103624 cites W2064364338 @default.
- W2055103624 cites W2066396908 @default.
- W2055103624 cites W2070720324 @default.
- W2055103624 cites W2072718947 @default.
- W2055103624 cites W2074457840 @default.
- W2055103624 cites W2075545465 @default.
- W2055103624 cites W2088327562 @default.
- W2055103624 cites W2091993603 @default.
- W2055103624 cites W2092120221 @default.
- W2055103624 cites W2093991561 @default.
- W2055103624 cites W2097072002 @default.
- W2055103624 cites W2098002265 @default.
- W2055103624 cites W2099042047 @default.
- W2055103624 cites W2103037305 @default.
- W2055103624 cites W2104198116 @default.
- W2055103624 cites W2108722540 @default.
- W2055103624 cites W2109049952 @default.
- W2055103624 cites W2110208125 @default.
- W2055103624 cites W2110437310 @default.
- W2055103624 cites W2113319997 @default.
- W2055103624 cites W2116136260 @default.
- W2055103624 cites W2117369739 @default.
- W2055103624 cites W2117556382 @default.
- W2055103624 cites W2118607380 @default.
- W2055103624 cites W2118992292 @default.
- W2055103624 cites W2121369614 @default.
- W2055103624 cites W2121747718 @default.
- W2055103624 cites W2125446880 @default.
- W2055103624 cites W2126255959 @default.
- W2055103624 cites W2127810520 @default.
- W2055103624 cites W2128359078 @default.
- W2055103624 cites W2129290484 @default.
- W2055103624 cites W2131541104 @default.
- W2055103624 cites W2139000972 @default.
- W2055103624 cites W2139344309 @default.
- W2055103624 cites W2141020690 @default.
- W2055103624 cites W2141585509 @default.
- W2055103624 cites W2142059961 @default.
- W2055103624 cites W2143200795 @default.
- W2055103624 cites W2143392673 @default.
- W2055103624 cites W2144519701 @default.
- W2055103624 cites W2146042128 @default.
- W2055103624 cites W2146437136 @default.
- W2055103624 cites W2147841362 @default.
- W2055103624 cites W2151721316 @default.
- W2055103624 cites W2156707195 @default.
- W2055103624 cites W2159813274 @default.
- W2055103624 cites W2160066016 @default.
- W2055103624 cites W2164731417 @default.
- W2055103624 cites W2170985506 @default.
- W2055103624 cites W2202712733 @default.
- W2055103624 cites W4248194214 @default.
- W2055103624 cites W834260560 @default.