FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055471247> ?p ?o ?g. }

• W2055471247 endingPage "226" @default.
• W2055471247 startingPage "221" @default.
• W2055471247 abstract "Despite the considerable body of evidence pointing to a possible relationship between the state of the adipose tissue depots and regulation of the somatotropic axis, to date the relationship between obesity and low growth hormone (GH) status remains incompletely understood. The low GH status in obesity is mainly considered as a functional condition, largely reversible after a sustained weight loss. Moreover, due to the effects of the adiposity on the regulation of the somatotropic axis, the application of GH stimulation tests in obesity may also lead to an incorrect diagnosis of GH deficieny (GHD). On the other hand, similar to patients with GHD unrelated to obesity, the reduced GH response to stimulation testing in obese individuals is associated with increased prevalence of cardiovascular risk factors and detrimental alterations of body composition, which contribute to worsening their cardio-metabolic risk profile. In addition, the reduced GH secretion may result in reduced serum insulin-like growth factor (IGF)-1 levels, and the concordance of low peak GH and low IGF-1 identifies a subset of obese individuals with high cardiovascular risk. Furthermore, after weight loss, the normalization of the GH response and IGF-1 levels may or may not occur, and in patients undergoing bariatric surgery the persistence of a low GH status may affect the post-operative outcomes. In this review, we will provide an overview on some clinically relevant aspects of the relationship between obesity axis and the somatotropic axis in the light of the recently published research." @default.
• W2055471247 created "2016-06-24" @default.
• W2055471247 creator A5003544129 @default.
• W2055471247 creator A5015141404 @default.
• W2055471247 creator A5066892710 @default.
• W2055471247 creator A5087293057 @default.
• W2055471247 date "2014-12-01" @default.
• W2055471247 modified "2023-09-25" @default.
• W2055471247 title "The complex relationship between obesity and the somatropic axis: The long and winding road" @default.
• W2055471247 cites W1485865796 @default.
• W2055471247 cites W1507898828 @default.
• W2055471247 cites W1969641540 @default.
• W2055471247 cites W1974226398 @default.
• W2055471247 cites W1975656299 @default.
• W2055471247 cites W1977783499 @default.
• W2055471247 cites W1977833491 @default.
• W2055471247 cites W1988876904 @default.
• W2055471247 cites W1994045846 @default.
• W2055471247 cites W1995437346 @default.
• W2055471247 cites W1996224452 @default.
• W2055471247 cites W1996263682 @default.
• W2055471247 cites W1998871426 @default.
• W2055471247 cites W2000359682 @default.
• W2055471247 cites W2003077563 @default.
• W2055471247 cites W2008535613 @default.
• W2055471247 cites W2010848180 @default.
• W2055471247 cites W2013606305 @default.
• W2055471247 cites W2017423404 @default.
• W2055471247 cites W2018070098 @default.
• W2055471247 cites W2023567665 @default.
• W2055471247 cites W2025089542 @default.
• W2055471247 cites W2028608010 @default.
• W2055471247 cites W2028965997 @default.
• W2055471247 cites W2031980352 @default.
• W2055471247 cites W2034401889 @default.
• W2055471247 cites W2039678052 @default.
• W2055471247 cites W2040920498 @default.
• W2055471247 cites W2045250642 @default.
• W2055471247 cites W2050295140 @default.
• W2055471247 cites W2056415845 @default.
• W2055471247 cites W2060649371 @default.
• W2055471247 cites W2063401920 @default.
• W2055471247 cites W2063701256 @default.
• W2055471247 cites W2069561445 @default.
• W2055471247 cites W2078417149 @default.
• W2055471247 cites W2079507623 @default.
• W2055471247 cites W2079607096 @default.
• W2055471247 cites W2082922896 @default.
• W2055471247 cites W2083807723 @default.
• W2055471247 cites W2084337381 @default.
• W2055471247 cites W2084490045 @default.
• W2055471247 cites W2086208641 @default.
• W2055471247 cites W2090627812 @default.
• W2055471247 cites W2091733618 @default.
• W2055471247 cites W2103019498 @default.
• W2055471247 cites W2107532860 @default.
• W2055471247 cites W2110647520 @default.
• W2055471247 cites W2113316936 @default.
• W2055471247 cites W2116768499 @default.
• W2055471247 cites W2120124435 @default.
• W2055471247 cites W2123796646 @default.
• W2055471247 cites W2126253416 @default.
• W2055471247 cites W2131406361 @default.
• W2055471247 cites W2136359274 @default.
• W2055471247 cites W2138489649 @default.
• W2055471247 cites W2143993437 @default.
• W2055471247 cites W2150345809 @default.
• W2055471247 cites W2160452185 @default.
• W2055471247 cites W2163182044 @default.
• W2055471247 cites W2163266320 @default.
• W2055471247 cites W2163459548 @default.
• W2055471247 cites W2165120659 @default.
• W2055471247 cites W2169295676 @default.
• W2055471247 doi "https://doi.org/10.1016/j.ghir.2014.09.002" @default.
• W2055471247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25315226" @default.
• W2055471247 hasPublicationYear "2014" @default.
• W2055471247 type Work @default.
• W2055471247 sameAs 2055471247 @default.
• W2055471247 citedByCount "64" @default.
• W2055471247 countsByYear W20554712472014 @default.
• W2055471247 countsByYear W20554712472015 @default.
• W2055471247 countsByYear W20554712472016 @default.
• W2055471247 countsByYear W20554712472017 @default.
• W2055471247 countsByYear W20554712472018 @default.
• W2055471247 countsByYear W20554712472019 @default.
• W2055471247 countsByYear W20554712472020 @default.
• W2055471247 countsByYear W20554712472021 @default.
• W2055471247 countsByYear W20554712472022 @default.
• W2055471247 countsByYear W20554712472023 @default.
• W2055471247 crossrefType "journal-article" @default.
• W2055471247 hasAuthorship W2055471247A5003544129 @default.
• W2055471247 hasAuthorship W2055471247A5015141404 @default.
• W2055471247 hasAuthorship W2055471247A5066892710 @default.
• W2055471247 hasAuthorship W2055471247A5087293057 @default.
• W2055471247 hasConcept C126322002 @default.
• W2055471247 hasConcept C134018914 @default.
• W2055471247 hasConcept C171089720 @default.
• W2055471247 hasConcept C2984496839 @default.

• next