Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057206798> ?p ?o ?g. }
- W2057206798 endingPage "137" @default.
- W2057206798 startingPage "131" @default.
- W2057206798 abstract "The thermal deactivation of TEM-1 β-lactamase was examined using two experimental techniques: a series of isothermal batch assays and a single, continuous, non-isothermal assay in an enzyme membrane reactor (EMR). The isothermal batch-mode technique was coupled with the three-state “Equilibrium Model” of enzyme deactivation, while the results of the EMR experiment were fitted to a four-state “molten globule model”. The two methods both led to the conclusions that the thermal deactivation of TEM-1 β-lactamase does not follow the Lumry-Eyring model and that the Teq of the enzyme (the point at which active and inactive states are present in equal amounts due to thermodynamic equilibrium) is at least 10 °C from the Tm (melting temperature), contrary to the idea that the true temperature optimum of a biocatalyst is necessarily close to the melting temperature." @default.
- W2057206798 created "2016-06-24" @default.
- W2057206798 creator A5011854424 @default.
- W2057206798 creator A5066495842 @default.
- W2057206798 creator A5080348602 @default.
- W2057206798 date "2009-08-24" @default.
- W2057206798 modified "2023-09-26" @default.
- W2057206798 title "Deactivation of TEM-1 β-Lactamase Investigated by Isothermal Batch and Non-Isothermal Continuous Enzyme Membrane Reactor Methods" @default.
- W2057206798 cites W1965238013 @default.
- W2057206798 cites W1974389044 @default.
- W2057206798 cites W1977962237 @default.
- W2057206798 cites W1980776051 @default.
- W2057206798 cites W1983533760 @default.
- W2057206798 cites W1983774444 @default.
- W2057206798 cites W1995706284 @default.
- W2057206798 cites W1997516494 @default.
- W2057206798 cites W1998752513 @default.
- W2057206798 cites W2001736575 @default.
- W2057206798 cites W2012913041 @default.
- W2057206798 cites W2022280363 @default.
- W2057206798 cites W2035184102 @default.
- W2057206798 cites W2046607300 @default.
- W2057206798 cites W2050465327 @default.
- W2057206798 cites W2060620101 @default.
- W2057206798 cites W2061521483 @default.
- W2057206798 cites W2071524746 @default.
- W2057206798 cites W2079257291 @default.
- W2057206798 cites W2126967119 @default.
- W2057206798 cites W2141350571 @default.
- W2057206798 cites W2158543301 @default.
- W2057206798 doi "https://doi.org/10.1002/cctc.200900120" @default.
- W2057206798 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3203640" @default.
- W2057206798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22039393" @default.
- W2057206798 hasPublicationYear "2009" @default.
- W2057206798 type Work @default.
- W2057206798 sameAs 2057206798 @default.
- W2057206798 citedByCount "13" @default.
- W2057206798 countsByYear W20572067982012 @default.
- W2057206798 countsByYear W20572067982013 @default.
- W2057206798 countsByYear W20572067982014 @default.
- W2057206798 countsByYear W20572067982015 @default.
- W2057206798 countsByYear W20572067982018 @default.
- W2057206798 countsByYear W20572067982021 @default.
- W2057206798 countsByYear W20572067982022 @default.
- W2057206798 countsByYear W20572067982023 @default.
- W2057206798 crossrefType "journal-article" @default.
- W2057206798 hasAuthorship W2057206798A5011854424 @default.
- W2057206798 hasAuthorship W2057206798A5066495842 @default.
- W2057206798 hasAuthorship W2057206798A5080348602 @default.
- W2057206798 hasBestOaLocation W20572067982 @default.
- W2057206798 hasConcept C121332964 @default.
- W2057206798 hasConcept C127413603 @default.
- W2057206798 hasConcept C133347239 @default.
- W2057206798 hasConcept C13530604 @default.
- W2057206798 hasConcept C178790620 @default.
- W2057206798 hasConcept C181199279 @default.
- W2057206798 hasConcept C185592680 @default.
- W2057206798 hasConcept C192562407 @default.
- W2057206798 hasConcept C33633552 @default.
- W2057206798 hasConcept C41625074 @default.
- W2057206798 hasConcept C42360764 @default.
- W2057206798 hasConcept C55493867 @default.
- W2057206798 hasConcept C97355855 @default.
- W2057206798 hasConcept C97488330 @default.
- W2057206798 hasConceptScore W2057206798C121332964 @default.
- W2057206798 hasConceptScore W2057206798C127413603 @default.
- W2057206798 hasConceptScore W2057206798C133347239 @default.
- W2057206798 hasConceptScore W2057206798C13530604 @default.
- W2057206798 hasConceptScore W2057206798C178790620 @default.
- W2057206798 hasConceptScore W2057206798C181199279 @default.
- W2057206798 hasConceptScore W2057206798C185592680 @default.
- W2057206798 hasConceptScore W2057206798C192562407 @default.
- W2057206798 hasConceptScore W2057206798C33633552 @default.
- W2057206798 hasConceptScore W2057206798C41625074 @default.
- W2057206798 hasConceptScore W2057206798C42360764 @default.
- W2057206798 hasConceptScore W2057206798C55493867 @default.
- W2057206798 hasConceptScore W2057206798C97355855 @default.
- W2057206798 hasConceptScore W2057206798C97488330 @default.
- W2057206798 hasIssue "1" @default.
- W2057206798 hasLocation W20572067981 @default.
- W2057206798 hasLocation W20572067982 @default.
- W2057206798 hasLocation W20572067983 @default.
- W2057206798 hasLocation W20572067984 @default.
- W2057206798 hasLocation W20572067985 @default.
- W2057206798 hasOpenAccess W2057206798 @default.
- W2057206798 hasPrimaryLocation W20572067981 @default.
- W2057206798 hasRelatedWork W1493701263 @default.
- W2057206798 hasRelatedWork W1965365622 @default.
- W2057206798 hasRelatedWork W1990078562 @default.
- W2057206798 hasRelatedWork W2057206798 @default.
- W2057206798 hasRelatedWork W2093720526 @default.
- W2057206798 hasRelatedWork W222589344 @default.
- W2057206798 hasRelatedWork W2293661256 @default.
- W2057206798 hasRelatedWork W2390293567 @default.
- W2057206798 hasRelatedWork W3022684477 @default.
- W2057206798 hasRelatedWork W31312704 @default.
- W2057206798 hasVolume "1" @default.
- W2057206798 isParatext "false" @default.