FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057367062> ?p ?o ?g. }

• W2057367062 endingPage "945" @default.
• W2057367062 startingPage "935" @default.
• W2057367062 abstract "Glutamine synthetase (GS) in the mosquito, Aedes aegypti, is induced in the midgut following a blood meal. Mosquito GS message is detected as soon as 1 h post-blood feeding and remains stable for 18 h. Using a PCR product encoding mosquito GS, a λgt10 adult female mosquito cDNA library was screened. A cDNA clone, pCl5A2, encoding the full translation product of mosquito GS was isolated and sequence analyses performed. Mosquito GS cDNA is 2.5 kb in length and its putative translation product shares all the conserved regions characteristic of the GS gene family, including the presumed ATP biding site. Glutamine synthetase activity in the mosquito midgut is highest at 18 h post-blood feeding. Activity can be detected over a broad pH range, from 6.0 to 7.5. Unlike other cellular GS enzymes, mosquito GS is not active in the presence of ATP. Very low dosages (0.05 mM) of L-methionine S-sulfoximine are sufficient to partially inhibit mosquito GS activity. Inhibition of GS disrupts the normal formation of the midgut peritrophic matrix, suggesting that GS enzyme might be involved in the initial pathway of chitin synthesis. The unique expression pattern and inducible nature of the mosquito GS gene make it an interesting candidate for studying promoter function. Additionally, the blood meal activation of the GS gene makes this a potentially valuable tool in mosquito transformation studies." @default.
• W2057367062 created "2016-06-24" @default.
• W2057367062 creator A5010275760 @default.
• W2057367062 creator A5047430621 @default.
• W2057367062 creator A5047490994 @default.
• W2057367062 creator A5070697792 @default.
• W2057367062 date "1998-12-01" @default.
• W2057367062 modified "2023-10-14" @default.
• W2057367062 title "Biochemical analysis of a blood meal-induced Aedes aegypti glutamine synthetase gene" @default.
• W2057367062 cites W1481052299 @default.
• W2057367062 cites W1491437859 @default.
• W2057367062 cites W1524995373 @default.
• W2057367062 cites W1534323632 @default.
• W2057367062 cites W1582517962 @default.
• W2057367062 cites W1889644880 @default.
• W2057367062 cites W1958912317 @default.
• W2057367062 cites W1966320967 @default.
• W2057367062 cites W1973190704 @default.
• W2057367062 cites W1977882911 @default.
• W2057367062 cites W1984087136 @default.
• W2057367062 cites W1987911729 @default.
• W2057367062 cites W1991723416 @default.
• W2057367062 cites W1994321218 @default.
• W2057367062 cites W1996372363 @default.
• W2057367062 cites W2005609689 @default.
• W2057367062 cites W2009310436 @default.
• W2057367062 cites W2009527472 @default.
• W2057367062 cites W2017913417 @default.
• W2057367062 cites W2022236187 @default.
• W2057367062 cites W2023147330 @default.
• W2057367062 cites W2025835879 @default.
• W2057367062 cites W2032931308 @default.
• W2057367062 cites W2045348184 @default.
• W2057367062 cites W2055043387 @default.
• W2057367062 cites W2058868228 @default.
• W2057367062 cites W2060277682 @default.
• W2057367062 cites W2061317980 @default.
• W2057367062 cites W2067922797 @default.
• W2057367062 cites W2069407260 @default.
• W2057367062 cites W2078643010 @default.
• W2057367062 cites W2081785697 @default.
• W2057367062 cites W2087646866 @default.
• W2057367062 cites W2088403592 @default.
• W2057367062 cites W2092133492 @default.
• W2057367062 cites W2100051093 @default.
• W2057367062 cites W2133449590 @default.
• W2057367062 cites W2134360245 @default.
• W2057367062 cites W2135947661 @default.
• W2057367062 cites W2156170609 @default.
• W2057367062 cites W2320367390 @default.
• W2057367062 cites W2398467441 @default.
• W2057367062 cites W2528023582 @default.
• W2057367062 cites W4231038249 @default.
• W2057367062 cites W4294216491 @default.
• W2057367062 cites W74811512 @default.
• W2057367062 doi "https://doi.org/10.1016/s0965-1748(98)00073-3" @default.
• W2057367062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9887510" @default.
• W2057367062 hasPublicationYear "1998" @default.
• W2057367062 type Work @default.
• W2057367062 sameAs 2057367062 @default.
• W2057367062 citedByCount "26" @default.
• W2057367062 countsByYear W20573670622012 @default.
• W2057367062 countsByYear W20573670622013 @default.
• W2057367062 countsByYear W20573670622016 @default.
• W2057367062 countsByYear W20573670622018 @default.
• W2057367062 countsByYear W20573670622019 @default.
• W2057367062 countsByYear W20573670622021 @default.
• W2057367062 countsByYear W20573670622022 @default.
• W2057367062 countsByYear W20573670622023 @default.
• W2057367062 crossrefType "journal-article" @default.
• W2057367062 hasAuthorship W2057367062A5010275760 @default.
• W2057367062 hasAuthorship W2057367062A5047430621 @default.
• W2057367062 hasAuthorship W2057367062A5047490994 @default.
• W2057367062 hasAuthorship W2057367062A5070697792 @default.
• W2057367062 hasConcept C104317684 @default.
• W2057367062 hasConcept C150149183 @default.
• W2057367062 hasConcept C153911025 @default.
• W2057367062 hasConcept C173758957 @default.
• W2057367062 hasConcept C187882448 @default.
• W2057367062 hasConcept C2776853612 @default.
• W2057367062 hasConcept C2777775583 @default.
• W2057367062 hasConcept C2777923404 @default.
• W2057367062 hasConcept C2779289688 @default.
• W2057367062 hasConcept C2779349466 @default.
• W2057367062 hasConcept C31903555 @default.
• W2057367062 hasConcept C515207424 @default.
• W2057367062 hasConcept C55493867 @default.
• W2057367062 hasConcept C59822182 @default.
• W2057367062 hasConcept C86803240 @default.
• W2057367062 hasConceptScore W2057367062C104317684 @default.
• W2057367062 hasConceptScore W2057367062C150149183 @default.
• W2057367062 hasConceptScore W2057367062C153911025 @default.
• W2057367062 hasConceptScore W2057367062C173758957 @default.
• W2057367062 hasConceptScore W2057367062C187882448 @default.
• W2057367062 hasConceptScore W2057367062C2776853612 @default.
• W2057367062 hasConceptScore W2057367062C2777775583 @default.
• W2057367062 hasConceptScore W2057367062C2777923404 @default.
• W2057367062 hasConceptScore W2057367062C2779289688 @default.

• next