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• W2057868306 abstract "<h2>Abstract</h2><h3>Objective</h3> To evaluate outcome of invasive gynecological re-interventions after uterine artery embolisation (UAE) in relation to leiomyoma characteristics. <h3>Design</h3> A cohort of 114 women with symptomatic myomas underwent UAE. Myoma characteristics were determined by contrast-enhanced magnetic resonance imaging (MRI) before and 6 months after treatment. The median follow-up time after UAE was 55.9 months; (range 20–116). Data on gynecological re-interventions were obtained for all patients and were analysed using the Kaplan–Meier method. Data were obtained on frequency of invasive re-interventions: major myoma procedures (hysterectomy, re-embolisation, laparoscopic or abdominal myomectomy) and outpatient hysteroscopic myoma procedures. Myoma characteristics with impact on outcome of re-interventions were determined by statistical analysis. <h3>Results</h3> Total re-intervention rate was 35.1%<i>.</i> Hysterectomy was performed due to myoma related symptoms in 6.1% of patients, but 23.7% of patients underwent additional uterine procedures, mainly outpatient hysteroscopy (15%). Major myoma re-intervention correlated with the extent of the infarct at follow-up MRI (<i>n</i>=107). Patients had undergone major re-intervention (3 years) as follows: infarct group C (<80%, <i>n</i>=16) 44%, infarct group B (80–99%, <i>n</i>=16) 19%, and infarct group A (100%, <i>n</i>=75) 10.1% ((<i>p</i><0.01) for both A vs B+C and A+B vs C). Major re-interventions were not associated with the presence of submucous myomas; but the hazard ratio (CI 95%) for undergoing hysteroscopic re-intervention was 8.4 (2–29) (<i>p</i>=0.001) in patients with submucous myomas, but 12.7 (5–35) (<i>p</i><0.0001) in patients with more than one submucous myomas. <h3>Conclusions</h3> Complete infarction after UAE reduces the need for major re-interventions. Assessment of complete infarction may be considered to improve quality in UAE procedures. Patients with more than one submucous myoma at UAE may often have hysteroscopic removal of residual myomas." @default.
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• W2057868306 date "2014-07-01" @default.
• W2057868306 modified "2023-09-24" @default.
• W2057868306 title "Re-intervention after uterine leiomyoma embolisation is related to incomplete infarction and presence of submucous leiomyomas" @default.
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• W2057868306 doi "https://doi.org/10.1016/j.ejogrb.2014.04.022" @default.
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