FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069845809> ?p ?o ?g. }

• W2069845809 endingPage "11680" @default.
• W2069845809 startingPage "11676" @default.
• W2069845809 abstract "We have analyzed the developmental pattern of beta-galactosidase (beta-gal) expression in the cerebral cortex of the beta 2nZ3'1 transgenic mouse line, which was generated using regulatory elements of the beta 2-microglobulin gene and shows ectopic expression in nervous tissue. From embryonic day 10 onward, beta-gal was expressed in the medial and dorsal cortices, including the hippocampal region, whereas lateral cortical areas were devoid of labeling. During the period of cortical neurogenesis (embryonic days 11-17), beta-gal was expressed by selective precursors in the proliferative ventricular zone of the neocortex and hippocampus, as well as by a number of migrating and postmigratory neurons arranged into narrow radial stripes above the labeled progenitors. Thus, the transgene labels a subset of cortical progenitors and their progeny. Postnatally, radial clusters of beta-gal-positive neurons were discernible until postpartum day 10. At this age, the clusters were 250 to 500 microns wide, composed of neurons spanning all the cortical layers and exhibiting several neuronal phenotypes. These data suggest molecular heterogeneity of cortical progenitors and of the cohorts of postmitotic neurons originating from them, which implies intrinsic molecular mosaicism in both cortical progenitors and developing neurons. Furthermore, the data show that neurons committed to the expression of the transgene migrate along very narrow, radial stripes." @default.
• W2069845809 created "2016-06-24" @default.
• W2069845809 creator A5002621185 @default.
• W2069845809 creator A5026856517 @default.
• W2069845809 creator A5028296039 @default.
• W2069845809 creator A5045991293 @default.
• W2069845809 creator A5047512959 @default.
• W2069845809 date "1995-12-05" @default.
• W2069845809 modified "2023-10-14" @default.
• W2069845809 title "Molecular heterogeneity of progenitors and radial migration in the developing cerebral cortex revealed by transgene expression." @default.
• W2069845809 cites W1487222554 @default.
• W2069845809 cites W1766321086 @default.
• W2069845809 cites W1916653587 @default.
• W2069845809 cites W1957995282 @default.
• W2069845809 cites W1969992168 @default.
• W2069845809 cites W1972775580 @default.
• W2069845809 cites W1973303770 @default.
• W2069845809 cites W1976084841 @default.
• W2069845809 cites W1984376163 @default.
• W2069845809 cites W1987070201 @default.
• W2069845809 cites W1988582833 @default.
• W2069845809 cites W1994406909 @default.
• W2069845809 cites W1998884675 @default.
• W2069845809 cites W2001550066 @default.
• W2069845809 cites W2005746771 @default.
• W2069845809 cites W2011959916 @default.
• W2069845809 cites W2025625968 @default.
• W2069845809 cites W2033410250 @default.
• W2069845809 cites W2036337207 @default.
• W2069845809 cites W2036442380 @default.
• W2069845809 cites W2046042221 @default.
• W2069845809 cites W2053965650 @default.
• W2069845809 cites W2054621947 @default.
• W2069845809 cites W2065081395 @default.
• W2069845809 cites W2081272393 @default.
• W2069845809 cites W2096813983 @default.
• W2069845809 cites W2097284437 @default.
• W2069845809 cites W2124348595 @default.
• W2069845809 cites W2130793535 @default.
• W2069845809 cites W2142003657 @default.
• W2069845809 cites W2399797271 @default.
• W2069845809 doi "https://doi.org/10.1073/pnas.92.25.11676" @default.
• W2069845809 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/40465" @default.
• W2069845809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8524827" @default.
• W2069845809 hasPublicationYear "1995" @default.
• W2069845809 type Work @default.
• W2069845809 sameAs 2069845809 @default.
• W2069845809 citedByCount "58" @default.
• W2069845809 countsByYear W20698458092013 @default.
• W2069845809 countsByYear W20698458092014 @default.
• W2069845809 countsByYear W20698458092016 @default.
• W2069845809 countsByYear W20698458092020 @default.
• W2069845809 countsByYear W20698458092022 @default.
• W2069845809 countsByYear W20698458092023 @default.
• W2069845809 crossrefType "journal-article" @default.
• W2069845809 hasAuthorship W2069845809A5002621185 @default.
• W2069845809 hasAuthorship W2069845809A5026856517 @default.
• W2069845809 hasAuthorship W2069845809A5028296039 @default.
• W2069845809 hasAuthorship W2069845809A5045991293 @default.
• W2069845809 hasAuthorship W2069845809A5047512959 @default.
• W2069845809 hasBestOaLocation W20698458092 @default.
• W2069845809 hasConcept C102230213 @default.
• W2069845809 hasConcept C104317684 @default.
• W2069845809 hasConcept C141035611 @default.
• W2069845809 hasConcept C145103041 @default.
• W2069845809 hasConcept C148762608 @default.
• W2069845809 hasConcept C15729860 @default.
• W2069845809 hasConcept C169760540 @default.
• W2069845809 hasConcept C201750760 @default.
• W2069845809 hasConcept C2777222312 @default.
• W2069845809 hasConcept C2777348757 @default.
• W2069845809 hasConcept C2781041448 @default.
• W2069845809 hasConcept C2781161787 @default.
• W2069845809 hasConcept C28328180 @default.
• W2069845809 hasConcept C4746552 @default.
• W2069845809 hasConcept C54355233 @default.
• W2069845809 hasConcept C86803240 @default.
• W2069845809 hasConcept C95444343 @default.
• W2069845809 hasConcept C97037327 @default.
• W2069845809 hasConceptScore W2069845809C102230213 @default.
• W2069845809 hasConceptScore W2069845809C104317684 @default.
• W2069845809 hasConceptScore W2069845809C141035611 @default.
• W2069845809 hasConceptScore W2069845809C145103041 @default.
• W2069845809 hasConceptScore W2069845809C148762608 @default.
• W2069845809 hasConceptScore W2069845809C15729860 @default.
• W2069845809 hasConceptScore W2069845809C169760540 @default.
• W2069845809 hasConceptScore W2069845809C201750760 @default.
• W2069845809 hasConceptScore W2069845809C2777222312 @default.
• W2069845809 hasConceptScore W2069845809C2777348757 @default.
• W2069845809 hasConceptScore W2069845809C2781041448 @default.
• W2069845809 hasConceptScore W2069845809C2781161787 @default.
• W2069845809 hasConceptScore W2069845809C28328180 @default.
• W2069845809 hasConceptScore W2069845809C4746552 @default.
• W2069845809 hasConceptScore W2069845809C54355233 @default.
• W2069845809 hasConceptScore W2069845809C86803240 @default.
• W2069845809 hasConceptScore W2069845809C95444343 @default.
• W2069845809 hasConceptScore W2069845809C97037327 @default.
• W2069845809 hasIssue "25" @default.

• next