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• W2071036258 abstract "We evaluated the immunological effects of a Kampo (Chinese) prescription Hochu-ekki-to (TJ-41) for 32 weeks and 1 week prophylactically in mice. The splenic natural killer cells (NK) of C57BL/6N mice prophylactically treated with TJ-41 for 32 weeks showed little enhanced cytotoxicity against NK-sensitive YAC-1 targets, but mice treated for 1 week showed significantly enhanced cytotoxicity. TJ-41 administration for 32 weeks increased the splenic NK cell population and CD4/CD8 significantly, but TJ-41 for 1 week was not affected. Further, there were no adverse effects of TJ-41 administration for 32 weeks. Whether or not that duration of administration can have the same beneficial effects on humans await further studies." @default.
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• W2071036258 date "2004-01-01" @default.
• W2071036258 modified "2023-10-17" @default.
• W2071036258 title "Evaluation of Immunological Effects of Hochu-ekki-to (TJ-41) Prophylactic Administration in Mice" @default.
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• W2071036258 doi "https://doi.org/10.1142/s0192415x04001898" @default.
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