FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071258496> ?p ?o ?g. }

• W2071258496 endingPage "234" @default.
• W2071258496 startingPage "229" @default.
• W2071258496 abstract "Purpose of review Recent therapeutic and observational studies have demonstrated improved survival with better management of haemostasis early after injury. This review delineates our current understanding of the clinical importance, aetiology and pathophysiology of acute traumatic coagulopathy (ATC). Recent findings Trauma causes an acute disruption of the equilibrium between all components of haemostasis (coagulation, anticoagulation, fibrinolysis, platelets and endothelium). In patients with a combination of severe tissue damage and systemic hypoperfusion, this will progress rapidly to an endogenous coagulopathy that is independently associated with worse outcomes. New discoveries of the interactions between neurohormonal, vascular, and coagulation systems are beginning to explain how this haemostatic impairment develops and offer novel targets for therapeutic manipulation. Routine coagulation screening tests are ineffective for diagnosing ATC and guiding resuscitation in real-time. Viscoelastic coagulation tests (such as ROTEM or TEG) have emerged as practical, rapid and sensitive diagnostic modalities. Their role in therapeutic targeting requires further validation. Summary Conventional concepts of traumatic coagulopathy as a late occurring condition in response to iatrogenic haemodilution are redundant. ATC is an endogenous impairment of haemostasis that begins at the moment of injury. Further outcome improvements are possible with better understanding of the process by which this coagulopathy develops and how it may be inhibited." @default.
• W2071258496 created "2016-06-24" @default.
• W2071258496 creator A5045191755 @default.
• W2071258496 creator A5048738726 @default.
• W2071258496 creator A5072546336 @default.
• W2071258496 date "2012-04-01" @default.
• W2071258496 modified "2023-10-04" @default.
• W2071258496 title "Acute traumatic coagulopathy" @default.
• W2071258496 cites W164804977 @default.
• W2071258496 cites W1883428116 @default.
• W2071258496 cites W1969319463 @default.
• W2071258496 cites W1970362985 @default.
• W2071258496 cites W1971410089 @default.
• W2071258496 cites W1992034786 @default.
• W2071258496 cites W2012264493 @default.
• W2071258496 cites W2040767898 @default.
• W2071258496 cites W2042109117 @default.
• W2071258496 cites W2050653657 @default.
• W2071258496 cites W2062474169 @default.
• W2071258496 cites W2081532052 @default.
• W2071258496 cites W2105453284 @default.
• W2071258496 cites W2126091538 @default.
• W2071258496 cites W2128128223 @default.
• W2071258496 cites W2130981676 @default.
• W2071258496 cites W2135531276 @default.
• W2071258496 cites W2136715209 @default.
• W2071258496 cites W2136753837 @default.
• W2071258496 cites W2137925656 @default.
• W2071258496 cites W2144080918 @default.
• W2071258496 cites W2146292166 @default.
• W2071258496 cites W2147183838 @default.
• W2071258496 cites W2151320901 @default.
• W2071258496 cites W2162249417 @default.
• W2071258496 cites W2163061022 @default.
• W2071258496 cites W2163395920 @default.
• W2071258496 cites W2165922907 @default.
• W2071258496 cites W2166219488 @default.
• W2071258496 cites W2324414036 @default.
• W2071258496 cites W4385356023 @default.
• W2071258496 doi "https://doi.org/10.1097/aco.0b013e3283509675" @default.
• W2071258496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22270921" @default.
• W2071258496 hasPublicationYear "2012" @default.
• W2071258496 type Work @default.
• W2071258496 sameAs 2071258496 @default.
• W2071258496 citedByCount "123" @default.
• W2071258496 countsByYear W20712584962012 @default.
• W2071258496 countsByYear W20712584962013 @default.
• W2071258496 countsByYear W20712584962014 @default.
• W2071258496 countsByYear W20712584962015 @default.
• W2071258496 countsByYear W20712584962016 @default.
• W2071258496 countsByYear W20712584962017 @default.
• W2071258496 countsByYear W20712584962018 @default.
• W2071258496 countsByYear W20712584962019 @default.
• W2071258496 countsByYear W20712584962020 @default.
• W2071258496 countsByYear W20712584962021 @default.
• W2071258496 countsByYear W20712584962022 @default.
• W2071258496 countsByYear W20712584962023 @default.
• W2071258496 crossrefType "journal-article" @default.
• W2071258496 hasAuthorship W2071258496A5045191755 @default.
• W2071258496 hasAuthorship W2071258496A5048738726 @default.
• W2071258496 hasAuthorship W2071258496A5072546336 @default.
• W2071258496 hasConcept C126322002 @default.
• W2071258496 hasConcept C141071460 @default.
• W2071258496 hasConcept C177713679 @default.
• W2071258496 hasConcept C26809991 @default.
• W2071258496 hasConcept C2776692886 @default.
• W2071258496 hasConcept C2776825266 @default.
• W2071258496 hasConcept C2777664302 @default.
• W2071258496 hasConcept C2778382381 @default.
• W2071258496 hasConcept C2778589496 @default.
• W2071258496 hasConcept C2779936836 @default.
• W2071258496 hasConcept C71924100 @default.
• W2071258496 hasConceptScore W2071258496C126322002 @default.
• W2071258496 hasConceptScore W2071258496C141071460 @default.
• W2071258496 hasConceptScore W2071258496C177713679 @default.
• W2071258496 hasConceptScore W2071258496C26809991 @default.
• W2071258496 hasConceptScore W2071258496C2776692886 @default.
• W2071258496 hasConceptScore W2071258496C2776825266 @default.
• W2071258496 hasConceptScore W2071258496C2777664302 @default.
• W2071258496 hasConceptScore W2071258496C2778382381 @default.
• W2071258496 hasConceptScore W2071258496C2778589496 @default.
• W2071258496 hasConceptScore W2071258496C2779936836 @default.
• W2071258496 hasConceptScore W2071258496C71924100 @default.
• W2071258496 hasIssue "2" @default.
• W2071258496 hasLocation W20712584961 @default.
• W2071258496 hasLocation W20712584962 @default.
• W2071258496 hasOpenAccess W2071258496 @default.
• W2071258496 hasPrimaryLocation W20712584961 @default.
• W2071258496 hasRelatedWork W1499447375 @default.
• W2071258496 hasRelatedWork W1563036944 @default.
• W2071258496 hasRelatedWork W1993751516 @default.
• W2071258496 hasRelatedWork W2466052074 @default.
• W2071258496 hasRelatedWork W2591203858 @default.
• W2071258496 hasRelatedWork W2992751618 @default.
• W2071258496 hasRelatedWork W3021729965 @default.
• W2071258496 hasRelatedWork W3152773974 @default.
• W2071258496 hasRelatedWork W4317940541 @default.
• W2071258496 hasRelatedWork W50364086 @default.

• next