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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077603704> ?p ?o ?g. }

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• W2077603704 abstract "A novel series of histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine template displaying low CYP2D6 and CYP3A4 inhibitory profiles has been identified. Structural features responsible for the reduction of P450 activity, a typical liability of 4-substituted imidazoles, have been established." @default.
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• W2077603704 date "2006-02-01" @default.
• W2077603704 modified "2023-10-09" @default.
• W2077603704 title "Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists" @default.
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• W2077603704 doi "https://doi.org/10.1016/j.bmcl.2005.10.087" @default.
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