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• W2077883934 abstract "Endoscopic submucosal dissection (ESD) was recently introduced as a treatment option for superficial adenocarcinoma of the esophagogastric junction (EGJ); however, its long-term clinical outcomes have not been fully evaluated.To assess the long-term outcomes of ESD for patients with superficial adenocarcinoma of the EGJ.Retrospective review from a single institution.University hospital.Fifty-eight patients, 46 men and 12 women (mean 69.3 years), with 39 T1m and 19 T1sm adenocarcinomas of the EGJ treated from June 2000 to May 2009.ESD procedures were performed with typical sequences.Complications, en bloc resection rate, curative resection rate, local recurrence, and distant metastases after ESD were evaluated. Curative resection is histologically defined as being free of resection margins and any evidence of deep submucosal invasion, undifferentiated carcinoma, and lymphovascular invasion.There were no major complications except for 3 patients with ulcer bleeding without the need for blood transfusion and 1 patient with esophageal stenosis. The rates of en bloc resection and curative resection were 100% and 79%, respectively. Twelve resections were histologically considered noncurative; these patients underwent additional ESD (n = 1) or surgical resection (n = 8). Local or distant recurrences were not observed in any patient achieving curative resection during follow-up (median 36.6 months, range 4-94 months).Retrospective design and single-site data collection.Long-term outcomes after ESD are favorable. ESD may be adopted as a treatment of choice for superficial adenocarcinoma of the EGJ." @default.
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• W2077883934 date "2010-11-01" @default.
• W2077883934 modified "2023-10-14" @default.
• W2077883934 title "Superficial adenocarcinoma of the esophagogastric junction: long-term results of endoscopic submucosal dissection" @default.
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• W2077883934 doi "https://doi.org/10.1016/j.gie.2010.07.030" @default.
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