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• W2078332965 abstract "This represents the first report of purification of a glutamine-rich antifungal peptide from family Amarylliaceace. The peptide, designated as nartazin, was purified from the bulbs of the Chinese daffodil Narcissus tazetta var. chinensis by means of ion-exchange chromatography and affinity chromatography. Its molecular mass was 7.1 kDa, as determined by SDS–PAGE and gel filtration. Nartazin stimulated proliferation of mouse splenocytes and bone marrow cells but inhibited proliferation of leukemia L1210 cells. It also inhibited translation in a cell-free rabbit reticulocyte lysate system. The sequence of its first 20 N-terminal residues was characterized by an abundance of glutamine. The peptide possessed antifungal activity on four phytopathogenic fungi. Its activity was retained after incubation with bovine trypsin and chymotrypsin (enzyme: substrate ratio 1:10 w/w) at 37 °C for 1 h but was attenuated after treatment with proteinase K. The data revealed its pronounced resistance to proteolytic digestion." @default.
• W2078332965 created "2016-06-24" @default.
• W2078332965 creator A5027108506 @default.
• W2078332965 creator A5035780833 @default.
• W2078332965 date "2004-12-01" @default.
• W2078332965 modified "2023-09-26" @default.
• W2078332965 title "First report of a glutamine-rich antifungal peptide with immunomodulatory and antiproliferative activities from family Amaryllidaceae" @default.
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• W2078332965 doi "https://doi.org/10.1016/j.bbrc.2004.10.013" @default.
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