Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079182608> ?p ?o ?g. }
- W2079182608 endingPage "320" @default.
- W2079182608 startingPage "315" @default.
- W2079182608 abstract "Objective According to data from animal models, complement activation plays a major role in the brain injury after acute ischemic stroke. Scarce findings are, however, available on the detection of complement activation products in stroke patients. Methods We have measured plasma levels of the five complement activation products (C1rC1sC1inh, C4d, C3a, C5a and SC5b-9) in samples of 26 patients with ischemic stroke upon admission. Twenty-six patients with severe carotid atherosclerosis served as patient controls. Results Levels of two activation products (SC5b-9 and C4d)) were significantly elevated in the plasma of stroke patients, SC5b-9 levels, exhibited significant positive correlation with the clinical severity of stroke, the severity of neurological deficit, as well as with the level of functional disability. Conclusion These findings suggest that complement activation plays an active role in the development of brain infarct. The measurement of complement activation products might help to determine the clinical prognosis after acute ischemic stroke. Furthermore, there is potential usefulness of complement modulating therapy in ischemic stroke." @default.
- W2079182608 created "2016-06-24" @default.
- W2079182608 creator A5018624537 @default.
- W2079182608 creator A5023931843 @default.
- W2079182608 creator A5031942816 @default.
- W2079182608 creator A5032729797 @default.
- W2079182608 creator A5042234744 @default.
- W2079182608 creator A5048650479 @default.
- W2079182608 creator A5064774239 @default.
- W2079182608 creator A5069419660 @default.
- W2079182608 creator A5081492922 @default.
- W2079182608 creator A5082420794 @default.
- W2079182608 creator A5088476938 @default.
- W2079182608 date "2009-05-01" @default.
- W2079182608 modified "2023-10-09" @default.
- W2079182608 title "Strong complement activation after acute ischemic stroke is associated with unfavorable outcomes" @default.
- W2079182608 cites W1541349172 @default.
- W2079182608 cites W1545877367 @default.
- W2079182608 cites W1588757304 @default.
- W2079182608 cites W1602285939 @default.
- W2079182608 cites W1763864485 @default.
- W2079182608 cites W1975101821 @default.
- W2079182608 cites W1981567607 @default.
- W2079182608 cites W1989192098 @default.
- W2079182608 cites W1997337646 @default.
- W2079182608 cites W1998816903 @default.
- W2079182608 cites W2015671694 @default.
- W2079182608 cites W2023572242 @default.
- W2079182608 cites W2032656726 @default.
- W2079182608 cites W2053751473 @default.
- W2079182608 cites W2056068526 @default.
- W2079182608 cites W2059673357 @default.
- W2079182608 cites W2067780026 @default.
- W2079182608 cites W2078858497 @default.
- W2079182608 cites W2080504768 @default.
- W2079182608 cites W2080883999 @default.
- W2079182608 cites W2085198524 @default.
- W2079182608 cites W2102406427 @default.
- W2079182608 cites W2118094114 @default.
- W2079182608 cites W2118483175 @default.
- W2079182608 cites W2118801006 @default.
- W2079182608 cites W2125889240 @default.
- W2079182608 cites W2130234373 @default.
- W2079182608 cites W2134088303 @default.
- W2079182608 cites W2155543365 @default.
- W2079182608 cites W2324553845 @default.
- W2079182608 cites W4251821107 @default.
- W2079182608 doi "https://doi.org/10.1016/j.atherosclerosis.2008.07.044" @default.
- W2079182608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18804761" @default.
- W2079182608 hasPublicationYear "2009" @default.
- W2079182608 type Work @default.
- W2079182608 sameAs 2079182608 @default.
- W2079182608 citedByCount "71" @default.
- W2079182608 countsByYear W20791826082012 @default.
- W2079182608 countsByYear W20791826082013 @default.
- W2079182608 countsByYear W20791826082014 @default.
- W2079182608 countsByYear W20791826082015 @default.
- W2079182608 countsByYear W20791826082016 @default.
- W2079182608 countsByYear W20791826082017 @default.
- W2079182608 countsByYear W20791826082018 @default.
- W2079182608 countsByYear W20791826082019 @default.
- W2079182608 countsByYear W20791826082020 @default.
- W2079182608 countsByYear W20791826082021 @default.
- W2079182608 countsByYear W20791826082022 @default.
- W2079182608 crossrefType "journal-article" @default.
- W2079182608 hasAuthorship W2079182608A5018624537 @default.
- W2079182608 hasAuthorship W2079182608A5023931843 @default.
- W2079182608 hasAuthorship W2079182608A5031942816 @default.
- W2079182608 hasAuthorship W2079182608A5032729797 @default.
- W2079182608 hasAuthorship W2079182608A5042234744 @default.
- W2079182608 hasAuthorship W2079182608A5048650479 @default.
- W2079182608 hasAuthorship W2079182608A5064774239 @default.
- W2079182608 hasAuthorship W2079182608A5069419660 @default.
- W2079182608 hasAuthorship W2079182608A5081492922 @default.
- W2079182608 hasAuthorship W2079182608A5082420794 @default.
- W2079182608 hasAuthorship W2079182608A5088476938 @default.
- W2079182608 hasConcept C104317684 @default.
- W2079182608 hasConcept C111684460 @default.
- W2079182608 hasConcept C112313634 @default.
- W2079182608 hasConcept C126322002 @default.
- W2079182608 hasConcept C127413603 @default.
- W2079182608 hasConcept C127716648 @default.
- W2079182608 hasConcept C159654299 @default.
- W2079182608 hasConcept C164705383 @default.
- W2079182608 hasConcept C185592680 @default.
- W2079182608 hasConcept C188082640 @default.
- W2079182608 hasConcept C203014093 @default.
- W2079182608 hasConcept C2776572282 @default.
- W2079182608 hasConcept C2778820722 @default.
- W2079182608 hasConcept C2780645631 @default.
- W2079182608 hasConcept C3020166492 @default.
- W2079182608 hasConcept C3020199598 @default.
- W2079182608 hasConcept C541997718 @default.
- W2079182608 hasConcept C55493867 @default.
- W2079182608 hasConcept C71924100 @default.
- W2079182608 hasConcept C78519656 @default.
- W2079182608 hasConceptScore W2079182608C104317684 @default.
- W2079182608 hasConceptScore W2079182608C111684460 @default.