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- W2082607534 endingPage "677" @default.
- W2082607534 startingPage "662" @default.
- W2082607534 abstract "The aetiology of OAL is undefined, although much attention has been recently focused on determining whether OAL is caused by an autoimmune disorder, chronic antigenic stimulation or both. It is becoming evident that infectious agents underlying chronic eye infection, as Chlamydia, may play a role in ocular lymphomagenesis. The high prevalence of Chlamydophila psittaci in patients with OAL has suggested a potential oncogenic role for its tendency to cause chronic and persistent infections, although it has been documented an evident geographical variability and response to antibiotic treatment. For C. pneumoniae, the findings so far obtained are very limited not only for identification in OAL but also for the specific treatment with antibiotics. The recent molecular and cultural evidence of C. trachomatis in patients with OAL, seems to suggest that also this pathogen may contribute to pathogenesis of such lymphoma. The potential application of bacteria-eradicating therapy at local and systemic level may ultimately result in safer and more efficient therapeutic option for patients affected by these malignancies. Moreover, a close collaboration between experts in ophthalmology, infectious diseases and hematology will help, in the future, to effectively manage this disease. This review attempts to weigh the currently available evidence regarding the role that Chlamydia play in development of OAL and focuses on patients with OAL observed at our Institution." @default.
- W2082607534 created "2016-06-24" @default.
- W2082607534 creator A5015936126 @default.
- W2082607534 creator A5026992937 @default.
- W2082607534 creator A5047791424 @default.
- W2082607534 creator A5062224908 @default.
- W2082607534 creator A5082402892 @default.
- W2082607534 date "2013-01-01" @default.
- W2082607534 modified "2023-10-02" @default.
- W2082607534 title "Role of Chlamydia in the Development of Ocular Adnexal Lymphoma" @default.
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