FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083765864> ?p ?o ?g. }

• W2083765864 endingPage "2955" @default.
• W2083765864 startingPage "2950" @default.
• W2083765864 abstract "The efficacy of granulocyte colony-stimulating factor (G-CSF) in reducing neutropenia and its associated complications in adults with acute lymphocytic leukemia (ALL) undergoing intensive chemotherapy in first remission was evaluated.Fourteen adult patients with ALL in first remission received intensive chemotherapy consisting of mitoxantrone 5 mg/m2 intravenously (IV) over 1 hour daily for 3 days, cytosine arabinoside (ara-C) 3 g/m2 IV over 2 hours every 12 hours x 4 on days 1 and 2, vincristine 2 mg IV on day 1, solumedrol 50 mg IV twice daily for 5 days, and G-CSF 5 micrograms/kg subcutaneously daily starting on day 4 until granulocyte recovery. Their outcome was compared with that of 14 consecutive patients who received the same intensification chemotherapy, but without G-CSF. The latter patients had been entered on the same ALL protocol from April 1990 through June 1991.G-CSF administration was associated with a significant shortening in the duration of neutropenia. The number of days to granulocyte recovery above 0.5 x 10(3)/microliters was 14 in the G-CSF group versus 18 days in the historical group (P < 0.001). Two episodes of documented infections were observed in the G-CSF group compared with four episodes in the historical group. Death during intensification therapy occurred in 2 of 14 patients in the historical group, but in none of the 14 patients receiving G-CSF.G-CSF as an adjunct to intensive chemotherapy in adults with ALL in first remission yielded positive results. Future studies incorporating growth factors supportive care during remission, induction, and consolidation may reduce treatment-related morbidity and mortality, increase the dose-intensity delivery of therapy, and potentially improve patient outcome." @default.
• W2083765864 created "2016-06-24" @default.
• W2083765864 creator A5006104041 @default.
• W2083765864 creator A5007152490 @default.
• W2083765864 creator A5014102823 @default.
• W2083765864 creator A5027575595 @default.
• W2083765864 creator A5030500582 @default.
• W2083765864 creator A5038399226 @default.
• W2083765864 creator A5057920623 @default.
• W2083765864 creator A5090435894 @default.
• W2083765864 date "1993-11-15" @default.
• W2083765864 modified "2023-10-12" @default.
• W2083765864 title "Granulocyte colony-stimulating factor supportive treatment following intensive chemotherapy in acute lymphocytic leukemia in first remission" @default.
• W2083765864 cites W1582130462 @default.
• W2083765864 cites W1602123006 @default.
• W2083765864 cites W1834314364 @default.
• W2083765864 cites W1888835857 @default.
• W2083765864 cites W1969194020 @default.
• W2083765864 cites W1974352352 @default.
• W2083765864 cites W1987951694 @default.
• W2083765864 cites W1997463506 @default.
• W2083765864 cites W2008650815 @default.
• W2083765864 cites W2012891007 @default.
• W2083765864 cites W2053906221 @default.
• W2083765864 cites W2122962750 @default.
• W2083765864 cites W2143594378 @default.
• W2083765864 cites W2254092548 @default.
• W2083765864 cites W2309356125 @default.
• W2083765864 cites W2313477330 @default.
• W2083765864 cites W2336096370 @default.
• W2083765864 cites W2337660074 @default.
• W2083765864 cites W2338649218 @default.
• W2083765864 cites W2341557816 @default.
• W2083765864 cites W2524290661 @default.
• W2083765864 cites W2593892363 @default.
• W2083765864 cites W323341750 @default.
• W2083765864 cites W4232587867 @default.
• W2083765864 cites W4233488038 @default.
• W2083765864 cites W4236767488 @default.
• W2083765864 cites W4241762497 @default.
• W2083765864 cites W4293241248 @default.
• W2083765864 doi "https://doi.org/10.1002/1097-0142(19931115)72:10<2950::aid-cncr2820721015>3.0.co;2-b" @default.
• W2083765864 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7693325" @default.
• W2083765864 hasPublicationYear "1993" @default.
• W2083765864 type Work @default.
• W2083765864 sameAs 2083765864 @default.
• W2083765864 citedByCount "28" @default.
• W2083765864 countsByYear W20837658642012 @default.
• W2083765864 countsByYear W20837658642017 @default.
• W2083765864 crossrefType "journal-article" @default.
• W2083765864 hasAuthorship W2083765864A5006104041 @default.
• W2083765864 hasAuthorship W2083765864A5007152490 @default.
• W2083765864 hasAuthorship W2083765864A5014102823 @default.
• W2083765864 hasAuthorship W2083765864A5027575595 @default.
• W2083765864 hasAuthorship W2083765864A5030500582 @default.
• W2083765864 hasAuthorship W2083765864A5038399226 @default.
• W2083765864 hasAuthorship W2083765864A5057920623 @default.
• W2083765864 hasAuthorship W2083765864A5090435894 @default.
• W2083765864 hasBestOaLocation W20837658641 @default.
• W2083765864 hasConcept C126322002 @default.
• W2083765864 hasConcept C141071460 @default.
• W2083765864 hasConcept C177713679 @default.
• W2083765864 hasConcept C2776694085 @default.
• W2083765864 hasConcept C2776755627 @default.
• W2083765864 hasConcept C2777063308 @default.
• W2083765864 hasConcept C2777767877 @default.
• W2083765864 hasConcept C2778041864 @default.
• W2083765864 hasConcept C2778461978 @default.
• W2083765864 hasConcept C2778850193 @default.
• W2083765864 hasConcept C2779429289 @default.
• W2083765864 hasConcept C2780923524 @default.
• W2083765864 hasConcept C2781107101 @default.
• W2083765864 hasConcept C2909962599 @default.
• W2083765864 hasConcept C2987404301 @default.
• W2083765864 hasConcept C71924100 @default.
• W2083765864 hasConcept C90924648 @default.
• W2083765864 hasConceptScore W2083765864C126322002 @default.
• W2083765864 hasConceptScore W2083765864C141071460 @default.
• W2083765864 hasConceptScore W2083765864C177713679 @default.
• W2083765864 hasConceptScore W2083765864C2776694085 @default.
• W2083765864 hasConceptScore W2083765864C2776755627 @default.
• W2083765864 hasConceptScore W2083765864C2777063308 @default.
• W2083765864 hasConceptScore W2083765864C2777767877 @default.
• W2083765864 hasConceptScore W2083765864C2778041864 @default.
• W2083765864 hasConceptScore W2083765864C2778461978 @default.
• W2083765864 hasConceptScore W2083765864C2778850193 @default.
• W2083765864 hasConceptScore W2083765864C2779429289 @default.
• W2083765864 hasConceptScore W2083765864C2780923524 @default.
• W2083765864 hasConceptScore W2083765864C2781107101 @default.
• W2083765864 hasConceptScore W2083765864C2909962599 @default.
• W2083765864 hasConceptScore W2083765864C2987404301 @default.
• W2083765864 hasConceptScore W2083765864C71924100 @default.
• W2083765864 hasConceptScore W2083765864C90924648 @default.
• W2083765864 hasIssue "10" @default.
• W2083765864 hasLocation W20837658641 @default.
• W2083765864 hasLocation W20837658642 @default.
• W2083765864 hasOpenAccess W2083765864 @default.
• W2083765864 hasPrimaryLocation W20837658641 @default.

• next