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- W2083842706 abstract "Although the effects of temperature changes on the activity of neurons have been studied in Aplysia, the reproducibility of the temperature dependence of the action potential (AP) parameters has not been verified. To this end, we performed experiments using Aplysia neurons. Fourteen AP parameters were analyzed using the long-term data series recorded during the experiments. Our analysis showed that nine of the AP parameters decreased as the temperature increased: the AP amplitude (AAP), membrane potential at the positive peak (Vpp), interspike interval, first half (Δtr1) and last half (Δtr2) of the temperature rising phase, first half (Δtf1) and last half (Δtf2) of the temperature falling phase, AP (ΔtAP, 1/2), and differentiated signal (ΔtDS, 1/2) half-width durations. Five of the AP parameters increased with temperature: the differentiated signal amplitude (ADS), absolute value of the membrane potential at negative peak (∣ Vnp ∣), absolute value of the maximum slope of the AP during the temperature rising (∣ –MSR ∣) and falling (∣–MSF∣) phases, and spiking frequency (Frequency). This work could provide the basis for a better understanding of the elementary processes underlying the temperature-dependent neuronal activity in Aplysia." @default.
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- W2083842706 date "2012-01-01" @default.
- W2083842706 modified "2023-10-16" @default.
- W2083842706 title "Temperature Dependence of Action Potential Parameters in<b><i>Aplysia</i></b>Neurons" @default.
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- W2083842706 doi "https://doi.org/10.1159/000334960" @default.
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