FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085335280> ?p ?o ?g. }

• W2085335280 endingPage "518" @default.
• W2085335280 startingPage "512" @default.
• W2085335280 abstract "Bivalent (IgG) and monovalent (Fab) antibodies isolated from antisperm autoantiserum of the guinea pig were tested for their effects on 1) the penetration of guinea pig anna pellucida by acrosome-reacted guinea pig spermatozoa and 2) the fusion of acrosome-reacted guinea pig spermatozoa with plasma membranes of guinea pig and hamster ova. In the presence of antiserum IgG, acrosome-reacted spermatozoa appeared as single, highly motile cells. They were completely prevented from interacting with guinea pig anna and from fusing with zona-free hamster ova, while their fusion with zona-free guinea pig ova was markedly inhibited. These cellular interactions were blocked, to a lesser degree, by monovalent (Fab) antibodies isolated from the same antisperm antiserum. IgG or Fab from normal guinea pig sera had no effect on these cellular interactions. Pretreatment of ova with antisperm IgG or Fab did not interfere with the interaction of ova with untreated acrosome-reacted spermatozoa. This study provides the first evidence that autoantigenic molecules on the surface and/or an intracellular membrane (e.g., the inner acrosomal membrane) of spermatozoa may be involved in the recognition of complementary ligands on the ova during the process of sperm-zona and sperm-vitellus interaction. It follows that blockage of these cellular events in fertilization by antireceptor antibodies is a potential mechanism whereby immune responses to sperm-specific antigens can render females infertile." @default.
• W2085335280 created "2016-06-24" @default.
• W2085335280 creator A5024596573 @default.
• W2085335280 creator A5034013570 @default.
• W2085335280 creator A5077596773 @default.
• W2085335280 date "1981-04-01" @default.
• W2085335280 modified "2023-10-17" @default.
• W2085335280 title "Sperm Autoantigens and Fertilization: II. Effects of Anti-Guinea Pig Sperm Autoantibodies on Sperm-Ovum Interactions" @default.
• W2085335280 cites W1547120483 @default.
• W2085335280 cites W1965135929 @default.
• W2085335280 cites W1971596565 @default.
• W2085335280 cites W1981089905 @default.
• W2085335280 cites W1981126949 @default.
• W2085335280 cites W1990776032 @default.
• W2085335280 cites W2001669418 @default.
• W2085335280 cites W2011500156 @default.
• W2085335280 cites W2017072756 @default.
• W2085335280 cites W2021263442 @default.
• W2085335280 cites W2026216984 @default.
• W2085335280 cites W2027395815 @default.
• W2085335280 cites W2031760716 @default.
• W2085335280 cites W2033975975 @default.
• W2085335280 cites W2035038774 @default.
• W2085335280 cites W2065679316 @default.
• W2085335280 cites W2068970184 @default.
• W2085335280 cites W2078829611 @default.
• W2085335280 cites W2100248383 @default.
• W2085335280 cites W2114397645 @default.
• W2085335280 cites W2128825219 @default.
• W2085335280 cites W2167232361 @default.
• W2085335280 cites W2184292228 @default.
• W2085335280 cites W2318423603 @default.
• W2085335280 cites W2340100375 @default.
• W2085335280 cites W2797564667 @default.
• W2085335280 cites W586614900 @default.
• W2085335280 cites W2619511860 @default.
• W2085335280 doi "https://doi.org/10.1095/biolreprod24.3.512" @default.
• W2085335280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7236816" @default.
• W2085335280 hasPublicationYear "1981" @default.
• W2085335280 type Work @default.
• W2085335280 sameAs 2085335280 @default.
• W2085335280 citedByCount "60" @default.
• W2085335280 countsByYear W20853352802018 @default.
• W2085335280 crossrefType "journal-article" @default.
• W2085335280 hasAuthorship W2085335280A5024596573 @default.
• W2085335280 hasAuthorship W2085335280A5034013570 @default.
• W2085335280 hasAuthorship W2085335280A5077596773 @default.
• W2085335280 hasConcept C105702510 @default.
• W2085335280 hasConcept C134018914 @default.
• W2085335280 hasConcept C153911025 @default.
• W2085335280 hasConcept C159654299 @default.
• W2085335280 hasConcept C16685009 @default.
• W2085335280 hasConcept C196843134 @default.
• W2085335280 hasConcept C203014093 @default.
• W2085335280 hasConcept C2776010925 @default.
• W2085335280 hasConcept C2776690073 @default.
• W2085335280 hasConcept C2778093475 @default.
• W2085335280 hasConcept C2778252442 @default.
• W2085335280 hasConcept C2778575167 @default.
• W2085335280 hasConcept C2778815084 @default.
• W2085335280 hasConcept C2779995066 @default.
• W2085335280 hasConcept C2781087480 @default.
• W2085335280 hasConcept C54355233 @default.
• W2085335280 hasConcept C71924100 @default.
• W2085335280 hasConcept C86803240 @default.
• W2085335280 hasConcept C88972607 @default.
• W2085335280 hasConcept C91523082 @default.
• W2085335280 hasConcept C95444343 @default.
• W2085335280 hasConceptScore W2085335280C105702510 @default.
• W2085335280 hasConceptScore W2085335280C134018914 @default.
• W2085335280 hasConceptScore W2085335280C153911025 @default.
• W2085335280 hasConceptScore W2085335280C159654299 @default.
• W2085335280 hasConceptScore W2085335280C16685009 @default.
• W2085335280 hasConceptScore W2085335280C196843134 @default.
• W2085335280 hasConceptScore W2085335280C203014093 @default.
• W2085335280 hasConceptScore W2085335280C2776010925 @default.
• W2085335280 hasConceptScore W2085335280C2776690073 @default.
• W2085335280 hasConceptScore W2085335280C2778093475 @default.
• W2085335280 hasConceptScore W2085335280C2778252442 @default.
• W2085335280 hasConceptScore W2085335280C2778575167 @default.
• W2085335280 hasConceptScore W2085335280C2778815084 @default.
• W2085335280 hasConceptScore W2085335280C2779995066 @default.
• W2085335280 hasConceptScore W2085335280C2781087480 @default.
• W2085335280 hasConceptScore W2085335280C54355233 @default.
• W2085335280 hasConceptScore W2085335280C71924100 @default.
• W2085335280 hasConceptScore W2085335280C86803240 @default.
• W2085335280 hasConceptScore W2085335280C88972607 @default.
• W2085335280 hasConceptScore W2085335280C91523082 @default.
• W2085335280 hasConceptScore W2085335280C95444343 @default.
• W2085335280 hasIssue "3" @default.
• W2085335280 hasLocation W20853352801 @default.
• W2085335280 hasLocation W20853352802 @default.
• W2085335280 hasOpenAccess W2085335280 @default.
• W2085335280 hasPrimaryLocation W20853352801 @default.
• W2085335280 hasRelatedWork W1948439622 @default.
• W2085335280 hasRelatedWork W1987038049 @default.
• W2085335280 hasRelatedWork W2010097848 @default.
• W2085335280 hasRelatedWork W2014382276 @default.

• next