Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091408045> ?p ?o ?g. }
- W2091408045 abstract "Oxygen represents an essential molecule for organisms. Because of this, sophisticated systems of sensors have evolved to monitor oxygenation of tissues. We propose that monoamine-synthesizing cells represent an important part of this system. It is well known that the carotid body, which contains chromaffin cells, serves as a chemical sensor of blood oxygenation. Similarly, the activity of adrenal medullary chromaffin cells is increased during hypoxia. Moreover, neurons located in the central nervous system containing catecholamines, serotonin, and histamine are also sensitive to hypoxia. On the basis of this common sensitivity of monoamine-synthesizing cells to changes in oxygenation we propose the hypothesis that these cells constitute a widely distributed network of sensors that monitor oxygen levels. The role of monoamine-synthesizing cells in monitoring tissue oxygen supply during both physiological and pathological conditions is also discussed." @default.
- W2091408045 created "2016-06-24" @default.
- W2091408045 creator A5026717959 @default.
- W2091408045 creator A5041619824 @default.
- W2091408045 date "2010-03-01" @default.
- W2091408045 modified "2023-09-24" @default.
- W2091408045 title "Do monoamine-synthesizing cells constitute a complex network of oxygen sensors?" @default.
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