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- W2100068043 abstract "Reactive oxygen species (ROS) are constantly produced in human beings under normal circumstances. Antioxidant systems help defend the body against ROS but may be overwhelmed during periods of oxidative stress, which can cause lipid peroxidation, damage to DNA, and cell death. Critical illness, such as sepsis or adult respiratory distress syndrome, can drastically increase the production of ROS and lead to oxidative stress. Sources of oxidative stress during critical illness include activation of the phagocytic cells of the immune system (the respiratory burst), the production of nitric oxide by the vascular endothelium, the release of iron and copper ions and metalloproteins, and the vascular damage caused by ischemia reperfusion. Only indirect measurements of ROS are available, but the presence of oxidative stress in critical illness is supported by clinical studies. In general, serum antioxidant vitamin concentrations seem to decrease and measures of oxidative stress seem to increase in critically ill populations. Oxidative stress has been associated with sepsis, shock, a need for mechanical ventilation, organ dysfunction, acute respiratory distress syndrome, disseminated intravascular coagulation, surgery, and the presence of an acute-phase response. In addition, higher levels of oxidative stress seem to occur in patients with more notable injuries. Dietary supplementation with antioxidant vitamins seems to be the logical answer to decreasing serum antioxidant concentrations, but antioxidants may have adverse effects. The benefit of supplementing antioxidants in critically ill populations has not been shown and requires further study." @default.
- W2100068043 created "2016-06-24" @default.
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- W2100068043 date "1998-09-01" @default.
- W2100068043 modified "2023-09-27" @default.
- W2100068043 title "Oxidative Stress in Critical Care" @default.
- W2100068043 cites W1247495390 @default.
- W2100068043 cites W1484882395 @default.
- W2100068043 cites W1525444530 @default.
- W2100068043 cites W1527767308 @default.
- W2100068043 cites W1545481155 @default.
- W2100068043 cites W1597488164 @default.
- W2100068043 cites W1597643123 @default.
- W2100068043 cites W1938228961 @default.
- W2100068043 cites W1966010545 @default.
- W2100068043 cites W1975577170 @default.
- W2100068043 cites W1978355469 @default.
- W2100068043 cites W1978967080 @default.
- W2100068043 cites W1980407353 @default.
- W2100068043 cites W1980526497 @default.
- W2100068043 cites W1980943812 @default.
- W2100068043 cites W1984454286 @default.
- W2100068043 cites W1984663779 @default.
- W2100068043 cites W1985131816 @default.
- W2100068043 cites W1989033613 @default.
- W2100068043 cites W1993664833 @default.
- W2100068043 cites W1996319836 @default.
- W2100068043 cites W1996716971 @default.
- W2100068043 cites W2000000986 @default.
- W2100068043 cites W2002769318 @default.
- W2100068043 cites W2003471941 @default.
- W2100068043 cites W2005629029 @default.
- W2100068043 cites W2006124405 @default.
- W2100068043 cites W2006294958 @default.
- W2100068043 cites W2008872268 @default.
- W2100068043 cites W2013156866 @default.
- W2100068043 cites W2013592393 @default.
- W2100068043 cites W2016218695 @default.
- W2100068043 cites W2019451160 @default.
- W2100068043 cites W2020209752 @default.
- W2100068043 cites W2025830885 @default.
- W2100068043 cites W2027651810 @default.
- W2100068043 cites W2036682827 @default.
- W2100068043 cites W2049775789 @default.
- W2100068043 cites W2050515690 @default.
- W2100068043 cites W2053011639 @default.
- W2100068043 cites W2053885482 @default.
- W2100068043 cites W2054969884 @default.
- W2100068043 cites W2058137293 @default.
- W2100068043 cites W2063547171 @default.
- W2100068043 cites W2076456149 @default.
- W2100068043 cites W2079496053 @default.
- W2100068043 cites W2081959177 @default.
- W2100068043 cites W2083631490 @default.
- W2100068043 cites W2086365400 @default.
- W2100068043 cites W2088306944 @default.
- W2100068043 cites W2089571522 @default.
- W2100068043 cites W2094042272 @default.
- W2100068043 cites W2099023343 @default.
- W2100068043 cites W2099131120 @default.
- W2100068043 cites W2107080012 @default.
- W2100068043 cites W2116220488 @default.
- W2100068043 cites W2119298408 @default.
- W2100068043 cites W2120121918 @default.
- W2100068043 cites W2120863479 @default.
- W2100068043 cites W2123460349 @default.
- W2100068043 cites W2141030751 @default.
- W2100068043 cites W2144556300 @default.
- W2100068043 cites W2148070809 @default.
- W2100068043 cites W2158757176 @default.
- W2100068043 cites W2260835883 @default.
- W2100068043 cites W2317242858 @default.
- W2100068043 cites W2338915269 @default.
- W2100068043 cites W2341500989 @default.
- W2100068043 cites W2501633378 @default.
- W2100068043 cites W4236652389 @default.
- W2100068043 cites W4236662689 @default.
- W2100068043 cites W4242467956 @default.
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- W2100068043 doi "https://doi.org/10.1016/s0002-8223(98)00230-2" @default.
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