FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100699056> ?p ?o ?g. }

• W2100699056 endingPage "R599" @default.
• W2100699056 startingPage "R591" @default.
• W2100699056 abstract "The aim of this study was to elucidate the mechanism responsible for lymphopenia after exercise. Seven young healthy men volunteered for this study. Peripheral blood mononuclear cells (PBMC) were cultured with cortisol and analyzed for C-X-C motif chemokine receptor 4 (CXCR4) expression by flow cytometry. To determine the effects of exercise, subjects performed exhaustive cycling exercise. PBMC were cultured with plasma obtained before and after the cycling exercise. Alternatively, PBMC obtained before and after exercise were cultured without plasma or glucocorticoid to examine whether PBMC were primed in vivo for CXCR4 expression. We analyzed cortisol- or plasma-treated PBMC to determine their ability to migrate through membrane filters in response to stromal cell-derived factor 1alpha/CXCL12. Cortisol dose- and time-dependently augmented CXCR4 expression on T lymphocytes, with <6 h of treatment sufficient to augment CXCR4 on T lymphocytes. Postexercise plasma also augmented CXCR4 expression. Cortisol or postexercise plasma treatment markedly enhanced migration of T lymphocytes toward CXCL12. Augmentation of CXCR4 on T lymphocytes by cortisol or plasma was effectively blocked by the glucocorticoid receptor antagonist RU-486. Thus exercise-elicited endogenous cortisol effectively augments CXCR4 expression on T lymphocytes, which may account for lymphopenia after exercise." @default.
• W2100699056 created "2016-06-24" @default.
• W2100699056 creator A5019310869 @default.
• W2100699056 creator A5028146410 @default.
• W2100699056 creator A5039192130 @default.
• W2100699056 creator A5074027917 @default.
• W2100699056 date "2005-03-01" @default.
• W2100699056 modified "2023-10-04" @default.
• W2100699056 title "Cortisol-induced CXCR4 augmentation mobilizes T lymphocytes after acute physical stress" @default.
• W2100699056 cites W1602835962 @default.
• W2100699056 cites W1648974646 @default.
• W2100699056 cites W1950281501 @default.
• W2100699056 cites W1964518559 @default.
• W2100699056 cites W1971794277 @default.
• W2100699056 cites W1972008047 @default.
• W2100699056 cites W1993983321 @default.
• W2100699056 cites W2001433846 @default.
• W2100699056 cites W2006187355 @default.
• W2100699056 cites W2010638326 @default.
• W2100699056 cites W2011626078 @default.
• W2100699056 cites W2016586685 @default.
• W2100699056 cites W2016723372 @default.
• W2100699056 cites W2024814903 @default.
• W2100699056 cites W2042735062 @default.
• W2100699056 cites W2043324873 @default.
• W2100699056 cites W2052586884 @default.
• W2100699056 cites W2060686995 @default.
• W2100699056 cites W2062718181 @default.
• W2100699056 cites W2071573827 @default.
• W2100699056 cites W2081769332 @default.
• W2100699056 cites W2083612980 @default.
• W2100699056 cites W2093255012 @default.
• W2100699056 cites W2098509726 @default.
• W2100699056 cites W2115706633 @default.
• W2100699056 cites W2135372888 @default.
• W2100699056 cites W2150833007 @default.
• W2100699056 cites W2156323704 @default.
• W2100699056 cites W2158294445 @default.
• W2100699056 cites W2160129587 @default.
• W2100699056 cites W2160272188 @default.
• W2100699056 cites W2172952050 @default.
• W2100699056 cites W2181976157 @default.
• W2100699056 cites W2182255695 @default.
• W2100699056 cites W2188020337 @default.
• W2100699056 cites W4231958907 @default.
• W2100699056 cites W4313341452 @default.
• W2100699056 doi "https://doi.org/10.1152/ajpregu.00438.2004" @default.
• W2100699056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15528395" @default.
• W2100699056 hasPublicationYear "2005" @default.
• W2100699056 type Work @default.
• W2100699056 sameAs 2100699056 @default.
• W2100699056 citedByCount "52" @default.
• W2100699056 countsByYear W21006990562012 @default.
• W2100699056 countsByYear W21006990562013 @default.
• W2100699056 countsByYear W21006990562014 @default.
• W2100699056 countsByYear W21006990562015 @default.
• W2100699056 countsByYear W21006990562016 @default.
• W2100699056 countsByYear W21006990562017 @default.
• W2100699056 countsByYear W21006990562018 @default.
• W2100699056 countsByYear W21006990562019 @default.
• W2100699056 countsByYear W21006990562020 @default.
• W2100699056 countsByYear W21006990562022 @default.
• W2100699056 countsByYear W21006990562023 @default.
• W2100699056 crossrefType "journal-article" @default.
• W2100699056 hasAuthorship W2100699056A5019310869 @default.
• W2100699056 hasAuthorship W2100699056A5028146410 @default.
• W2100699056 hasAuthorship W2100699056A5039192130 @default.
• W2100699056 hasAuthorship W2100699056A5074027917 @default.
• W2100699056 hasConcept C126322002 @default.
• W2100699056 hasConcept C129470790 @default.
• W2100699056 hasConcept C13373296 @default.
• W2100699056 hasConcept C134018914 @default.
• W2100699056 hasConcept C137061746 @default.
• W2100699056 hasConcept C170493617 @default.
• W2100699056 hasConcept C202751555 @default.
• W2100699056 hasConcept C203014093 @default.
• W2100699056 hasConcept C2777761686 @default.
• W2100699056 hasConcept C2780841215 @default.
• W2100699056 hasConcept C553184892 @default.
• W2100699056 hasConcept C55493867 @default.
• W2100699056 hasConcept C59493245 @default.
• W2100699056 hasConcept C71924100 @default.
• W2100699056 hasConcept C86803240 @default.
• W2100699056 hasConceptScore W2100699056C126322002 @default.
• W2100699056 hasConceptScore W2100699056C129470790 @default.
• W2100699056 hasConceptScore W2100699056C13373296 @default.
• W2100699056 hasConceptScore W2100699056C134018914 @default.
• W2100699056 hasConceptScore W2100699056C137061746 @default.
• W2100699056 hasConceptScore W2100699056C170493617 @default.
• W2100699056 hasConceptScore W2100699056C202751555 @default.
• W2100699056 hasConceptScore W2100699056C203014093 @default.
• W2100699056 hasConceptScore W2100699056C2777761686 @default.
• W2100699056 hasConceptScore W2100699056C2780841215 @default.
• W2100699056 hasConceptScore W2100699056C553184892 @default.
• W2100699056 hasConceptScore W2100699056C55493867 @default.
• W2100699056 hasConceptScore W2100699056C59493245 @default.
• W2100699056 hasConceptScore W2100699056C71924100 @default.
• W2100699056 hasConceptScore W2100699056C86803240 @default.

• next