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- W2106191107 startingPage "220S" @default.
- W2106191107 abstract "The vascular and potentially hypertensive actions of the calcium-regulating hormones 1,25-dihydroxychole-calciferol [1,25(OH)2D3], parathyroid hormone (PTH), and calcitonin and related factors such as parathyroid hypertensive factor (PHF) and calcitonin gene-related peptide (CGRP) are discussed. 1,25(OH)2D3 has inotropic and calciotropic actions on isolated vascular tissue whereas PTH is a vasodilator. PHF, which has been reported in plasma of humans with essential hypertension and spontaneously hypertensive rats, has both pressor and calciotropic actions. Calcitonin is without vascular effects and CGRP is a potent vasodilator. It is concluded that several of the hormones responsible for maintaining Ca2+ homeostasis modulate vascular Ca2+ metabolism and force generating capacity. These substances may be long-term modulators of vascular function and play a role in the determination of peripheral vascular resistance." @default.
- W2106191107 created "2016-06-24" @default.
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- W2106191107 date "1991-07-01" @default.
- W2106191107 modified "2023-10-16" @default.
- W2106191107 title "Calcium-regulating hormones in hypertension: vascular actions" @default.
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- W2106191107 doi "https://doi.org/10.1093/ajcn/54.1.220s" @default.
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