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• W2106615145 abstract "Article history Hydrotropy is one of the important solubility enhancement techniques that can be used to enhance solubilisation of poorly water soluble drugs in folds by using various hydrotropic agents. Hydrotropic agents such as sodium citrate, sodium acetate, sodium benzoate, urea, nicotinamide are commonly used. Mechanism of hydrotropic solubilisation is by salting in or by stacking complexation. Hydrotropic agents can be classified generally or on the basis of chemical structure. Hydrotropy is used in the analysis of active pharmaceutical ingredients to skip use of organic solvents that means it is eco-friendly method. It is used in solid dosage forms, injections and separation of closely boiling liquids, in novel systems. To achieve highest degree of solubility hydrotropes can be combined with polymers or co- solvents as in mixed hydrotropy." @default.
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• W2106615145 date "2013-01-01" @default.
• W2106615145 modified "2023-09-22" @default.
• W2106615145 title "A REVIEW ON: NOVEL SOLUBILITY ENHANCEMENT TECHNIQUE HYDROTROPY" @default.
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