FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110553669> ?p ?o ?g. }

• W2110553669 endingPage "424" @default.
• W2110553669 startingPage "411" @default.
• W2110553669 abstract "Blumea balsamifera (also known as sambong), a medicinal plant, is known to improve physiological disorders such as rheumatism and hypertension. However, its anticancer activity has not been well elucidated. In this study, we found that Blumea balsamifera MeOH extract (BME) induced growth inhibitory activity in rat and human hepatocellular carcinoma cells (McA-RH7777, HepG2, respectively) without cytotoxicity as in with rat hepatocytes used as a normal cell model. BME induced cell cycle arrest at G1 phase via decreases in expression of cyclin-E and phosphorylation of retinoblastoma (Rb) protein in both dose- and time-dependent manners. Furthermore, BME reduced the level of a proliferation related ligand (APRIL) which stimulates tumor cell growth. The anti-proliferative effect of BME was improved slightly but significantly by the treatment with recombinant human APRIL. These findings suggest that BME may have a possible therapeutic potential in hepatoma cancer patients and the depletion of cellular APRIL may be one of the important mechanisms on the growth inhibitory effect of BME." @default.
• W2110553669 created "2016-06-24" @default.
• W2110553669 creator A5004435095 @default.
• W2110553669 creator A5009123578 @default.
• W2110553669 creator A5025671398 @default.
• W2110553669 creator A5032316769 @default.
• W2110553669 creator A5036261290 @default.
• W2110553669 creator A5037389181 @default.
• W2110553669 creator A5055578127 @default.
• W2110553669 creator A5067852589 @default.
• W2110553669 creator A5071149274 @default.
• W2110553669 date "2008-01-01" @default.
• W2110553669 modified "2023-09-27" @default.
• W2110553669 title "Anticancer Activities and Mechanisms of <i>Blumea balsamifera</i> Extract in Hepatocellular Carcinoma Cells" @default.
• W2110553669 cites W1597011288 @default.
• W2110553669 cites W1970741091 @default.
• W2110553669 cites W2012016369 @default.
• W2110553669 cites W2021760512 @default.
• W2110553669 cites W2033296455 @default.
• W2110553669 cites W2034269086 @default.
• W2110553669 cites W2036571570 @default.
• W2110553669 cites W2037257739 @default.
• W2110553669 cites W2051256348 @default.
• W2110553669 cites W2054363550 @default.
• W2110553669 cites W2055595737 @default.
• W2110553669 cites W2055816409 @default.
• W2110553669 cites W2092913557 @default.
• W2110553669 cites W2115225962 @default.
• W2110553669 cites W2115528666 @default.
• W2110553669 cites W2132229312 @default.
• W2110553669 cites W2139983785 @default.
• W2110553669 cites W2146620829 @default.
• W2110553669 cites W2154533573 @default.
• W2110553669 cites W2159052529 @default.
• W2110553669 cites W2162331245 @default.
• W2110553669 cites W2163557371 @default.
• W2110553669 cites W2177166422 @default.
• W2110553669 cites W4250393576 @default.
• W2110553669 cites W4293247451 @default.
• W2110553669 doi "https://doi.org/10.1142/s0192415x08005862" @default.
• W2110553669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18457370" @default.
• W2110553669 hasPublicationYear "2008" @default.
• W2110553669 type Work @default.
• W2110553669 sameAs 2110553669 @default.
• W2110553669 citedByCount "31" @default.
• W2110553669 countsByYear W21105536692012 @default.
• W2110553669 countsByYear W21105536692014 @default.
• W2110553669 countsByYear W21105536692015 @default.
• W2110553669 countsByYear W21105536692016 @default.
• W2110553669 countsByYear W21105536692017 @default.
• W2110553669 countsByYear W21105536692020 @default.
• W2110553669 countsByYear W21105536692021 @default.
• W2110553669 countsByYear W21105536692022 @default.
• W2110553669 countsByYear W21105536692023 @default.
• W2110553669 crossrefType "journal-article" @default.
• W2110553669 hasAuthorship W2110553669A5004435095 @default.
• W2110553669 hasAuthorship W2110553669A5009123578 @default.
• W2110553669 hasAuthorship W2110553669A5025671398 @default.
• W2110553669 hasAuthorship W2110553669A5032316769 @default.
• W2110553669 hasAuthorship W2110553669A5036261290 @default.
• W2110553669 hasAuthorship W2110553669A5037389181 @default.
• W2110553669 hasAuthorship W2110553669A5055578127 @default.
• W2110553669 hasAuthorship W2110553669A5067852589 @default.
• W2110553669 hasAuthorship W2110553669A5071149274 @default.
• W2110553669 hasConcept C104317684 @default.
• W2110553669 hasConcept C109316439 @default.
• W2110553669 hasConcept C1491633281 @default.
• W2110553669 hasConcept C190283241 @default.
• W2110553669 hasConcept C199835354 @default.
• W2110553669 hasConcept C202751555 @default.
• W2110553669 hasConcept C2776062698 @default.
• W2110553669 hasConcept C2776577112 @default.
• W2110553669 hasConcept C2778019345 @default.
• W2110553669 hasConcept C29537977 @default.
• W2110553669 hasConcept C40767141 @default.
• W2110553669 hasConcept C502942594 @default.
• W2110553669 hasConcept C55493867 @default.
• W2110553669 hasConcept C556039675 @default.
• W2110553669 hasConcept C62112901 @default.
• W2110553669 hasConcept C71924100 @default.
• W2110553669 hasConcept C86803240 @default.
• W2110553669 hasConcept C98274493 @default.
• W2110553669 hasConceptScore W2110553669C104317684 @default.
• W2110553669 hasConceptScore W2110553669C109316439 @default.
• W2110553669 hasConceptScore W2110553669C1491633281 @default.
• W2110553669 hasConceptScore W2110553669C190283241 @default.
• W2110553669 hasConceptScore W2110553669C199835354 @default.
• W2110553669 hasConceptScore W2110553669C202751555 @default.
• W2110553669 hasConceptScore W2110553669C2776062698 @default.
• W2110553669 hasConceptScore W2110553669C2776577112 @default.
• W2110553669 hasConceptScore W2110553669C2778019345 @default.
• W2110553669 hasConceptScore W2110553669C29537977 @default.
• W2110553669 hasConceptScore W2110553669C40767141 @default.
• W2110553669 hasConceptScore W2110553669C502942594 @default.
• W2110553669 hasConceptScore W2110553669C55493867 @default.
• W2110553669 hasConceptScore W2110553669C556039675 @default.
• W2110553669 hasConceptScore W2110553669C62112901 @default.
• W2110553669 hasConceptScore W2110553669C71924100 @default.

• next