FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115280756> ?p ?o ?g. }

• W2115280756 endingPage "157" @default.
• W2115280756 startingPage "152" @default.
• W2115280756 abstract "The relative roles of Kupffer cells, complement, and specific antibody in liver antimicrobial activities were investigated by using a rat liver perfusion model. Normal livers trapped an average of 60% of Salmonella typhimurium in a single pass and in the presence of plasma killed more than 60% of these organisms in 30 min. Livers depleted of Kupffer cell function by silica treatment had significantly less bactericidal ability (ca. 15%) in the presence of plasma, showing that viable Kupffer cells are required for optimal antimicrobial activity. To determine the importance of complement in Salmonella killing, plasma complement activity was inhibited by heating at 57 and 50°C, zymosan absorption, chelation with disodium ethylenediaminetetraacetate (EDTA) and depletion of rat C3 by using specific immunoabsorbent. All treatments significantly reduced bactericidal activity in the perfused liver. Chelation of plasma with EDTA had no effect, suggesting that the alternate and not the classical pathway for complement activation was involved. Immune plasma alone was bactericidal. When immune plasma was heated, zymosan absorbed, or chelated with EDTA, bactericidal activity was inhibited in the perfused liver, but bacterial trapping increased. These results suggest that complement is required for bactericidal activity in perfused livers and that specific antibody only enhances bacterial trapping." @default.
• W2115280756 created "2016-06-24" @default.
• W2115280756 creator A5032038095 @default.
• W2115280756 creator A5076887178 @default.
• W2115280756 date "1980-07-01" @default.
• W2115280756 modified "2023-09-23" @default.
• W2115280756 title "Role of Kupffer Cells, Complement, and Specific Antibody in Bactericidal Activities of Perfused Livers" @default.
• W2115280756 cites W1416261912 @default.
• W2115280756 cites W1493561788 @default.
• W2115280756 cites W1519265737 @default.
• W2115280756 cites W1531644278 @default.
• W2115280756 cites W1538060285 @default.
• W2115280756 cites W1764541696 @default.
• W2115280756 cites W1808460297 @default.
• W2115280756 cites W1902063958 @default.
• W2115280756 cites W2053863419 @default.
• W2115280756 cites W2071552364 @default.
• W2115280756 cites W2075021105 @default.
• W2115280756 cites W2076721441 @default.
• W2115280756 cites W2096376679 @default.
• W2115280756 cites W2111031157 @default.
• W2115280756 cites W2123062093 @default.
• W2115280756 cites W2141732883 @default.
• W2115280756 cites W2170546609 @default.
• W2115280756 cites W2204091025 @default.
• W2115280756 cites W2286001411 @default.
• W2115280756 cites W2302424087 @default.
• W2115280756 cites W2409419350 @default.
• W2115280756 cites W60436086 @default.
• W2115280756 cites W643932773 @default.
• W2115280756 cites W1486232015 @default.
• W2115280756 doi "https://doi.org/10.1128/iai.29.1.152-157.1980" @default.
• W2115280756 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/551088" @default.
• W2115280756 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6995334" @default.
• W2115280756 hasPublicationYear "1980" @default.
• W2115280756 type Work @default.
• W2115280756 sameAs 2115280756 @default.
• W2115280756 citedByCount "24" @default.
• W2115280756 countsByYear W21152807562015 @default.
• W2115280756 crossrefType "journal-article" @default.
• W2115280756 hasAuthorship W2115280756A5032038095 @default.
• W2115280756 hasAuthorship W2115280756A5076887178 @default.
• W2115280756 hasBestOaLocation W21152807561 @default.
• W2115280756 hasConcept C111684460 @default.
• W2115280756 hasConcept C159654299 @default.
• W2115280756 hasConcept C160448771 @default.
• W2115280756 hasConcept C168507396 @default.
• W2115280756 hasConcept C178790620 @default.
• W2115280756 hasConcept C185592680 @default.
• W2115280756 hasConcept C189446657 @default.
• W2115280756 hasConcept C197404232 @default.
• W2115280756 hasConcept C202751555 @default.
• W2115280756 hasConcept C203014093 @default.
• W2115280756 hasConcept C2778870864 @default.
• W2115280756 hasConcept C2778904781 @default.
• W2115280756 hasConcept C2781065037 @default.
• W2115280756 hasConcept C4937899 @default.
• W2115280756 hasConcept C523546767 @default.
• W2115280756 hasConcept C54355233 @default.
• W2115280756 hasConcept C55493867 @default.
• W2115280756 hasConcept C86803240 @default.
• W2115280756 hasConcept C8891405 @default.
• W2115280756 hasConcept C89372155 @default.
• W2115280756 hasConcept C89423630 @default.
• W2115280756 hasConceptScore W2115280756C111684460 @default.
• W2115280756 hasConceptScore W2115280756C159654299 @default.
• W2115280756 hasConceptScore W2115280756C160448771 @default.
• W2115280756 hasConceptScore W2115280756C168507396 @default.
• W2115280756 hasConceptScore W2115280756C178790620 @default.
• W2115280756 hasConceptScore W2115280756C185592680 @default.
• W2115280756 hasConceptScore W2115280756C189446657 @default.
• W2115280756 hasConceptScore W2115280756C197404232 @default.
• W2115280756 hasConceptScore W2115280756C202751555 @default.
• W2115280756 hasConceptScore W2115280756C203014093 @default.
• W2115280756 hasConceptScore W2115280756C2778870864 @default.
• W2115280756 hasConceptScore W2115280756C2778904781 @default.
• W2115280756 hasConceptScore W2115280756C2781065037 @default.
• W2115280756 hasConceptScore W2115280756C4937899 @default.
• W2115280756 hasConceptScore W2115280756C523546767 @default.
• W2115280756 hasConceptScore W2115280756C54355233 @default.
• W2115280756 hasConceptScore W2115280756C55493867 @default.
• W2115280756 hasConceptScore W2115280756C86803240 @default.
• W2115280756 hasConceptScore W2115280756C8891405 @default.
• W2115280756 hasConceptScore W2115280756C89372155 @default.
• W2115280756 hasConceptScore W2115280756C89423630 @default.
• W2115280756 hasIssue "1" @default.
• W2115280756 hasLocation W21152807561 @default.
• W2115280756 hasLocation W21152807562 @default.
• W2115280756 hasLocation W21152807563 @default.
• W2115280756 hasOpenAccess W2115280756 @default.
• W2115280756 hasPrimaryLocation W21152807561 @default.
• W2115280756 hasRelatedWork W1848183260 @default.
• W2115280756 hasRelatedWork W1855022079 @default.
• W2115280756 hasRelatedWork W1935132701 @default.
• W2115280756 hasRelatedWork W1983872845 @default.
• W2115280756 hasRelatedWork W2040489462 @default.
• W2115280756 hasRelatedWork W2051857895 @default.
• W2115280756 hasRelatedWork W2053062491 @default.

• next