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• W2116724182 abstract "ABSTRACT To evaluate the role of the zinc-binding metalloprotease in Bacteroides fragilis toxin (BFT) processing and activity, the zinc-binding consensus sequences (H348, E349, H352, G355, H358, and M366) were mutated by site-directed-mutagenesis. Our results indicated that single point mutations in the zinc-binding metalloprotease motif do not affect BFT processing but do reduce or eliminate BFT biologic activity in vitro." @default.
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• W2116724182 date "2005-08-01" @default.
• W2116724182 modified "2023-09-23" @default.
• W2116724182 title "Mutation of the Zinc-Binding Metalloprotease Motif Affects<i>Bacteroides fragilis</i>Toxin Activity but Does Not Affect Propeptide Processing" @default.
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• W2116724182 doi "https://doi.org/10.1128/iai.73.8.5273-5277.2005" @default.
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