FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116743728> ?p ?o ?g. }

• W2116743728 endingPage "18630" @default.
• W2116743728 startingPage "18625" @default.
• W2116743728 abstract "Significance Events that occur between entry of the HIV-1 capsid into the cytoplasm of the target cell and the delivery of the viral genetic material into the nucleus constitute some of the less well understood processes in the viral life cycle. We demonstrated that PF74, a small-molecule inhibitor of HIV-1, and the host proteins CPSF6 and NUP153 bind to a preformed pocket within the CA protein hexamers that exist within the assembled capsid. Our results suggest that key features of the CA hexameric lattice remain intact upon docking at the nuclear pore. In addition, low molecular weight ligands that better mimic virus–host, protein–protein interactions at the intersubunit interfaces within the assembled viral capsid may offer novel avenues for therapeutic intervention." @default.
• W2116743728 created "2016-06-24" @default.
• W2116743728 creator A5015481124 @default.
• W2116743728 creator A5018020732 @default.
• W2116743728 creator A5018268636 @default.
• W2116743728 creator A5044615289 @default.
• W2116743728 creator A5052538293 @default.
• W2116743728 creator A5054673621 @default.
• W2116743728 creator A5060458363 @default.
• W2116743728 creator A5065620364 @default.
• W2116743728 creator A5070557615 @default.
• W2116743728 creator A5073015383 @default.
• W2116743728 creator A5077172319 @default.
• W2116743728 creator A5083959244 @default.
• W2116743728 date "2014-12-17" @default.
• W2116743728 modified "2023-10-17" @default.
• W2116743728 title "Structural basis of HIV-1 capsid recognition by PF74 and CPSF6" @default.
• W2116743728 cites W1964022123 @default.
• W2116743728 cites W1985849199 @default.
• W2116743728 cites W1994410560 @default.
• W2116743728 cites W1997819439 @default.
• W2116743728 cites W2000218608 @default.
• W2116743728 cites W2003527687 @default.
• W2116743728 cites W2013652077 @default.
• W2116743728 cites W2021064626 @default.
• W2116743728 cites W2033637003 @default.
• W2116743728 cites W2034500663 @default.
• W2116743728 cites W2034606779 @default.
• W2116743728 cites W2044993753 @default.
• W2116743728 cites W2050963564 @default.
• W2116743728 cites W2056741297 @default.
• W2116743728 cites W2077915242 @default.
• W2116743728 cites W2092609668 @default.
• W2116743728 cites W2094692623 @default.
• W2116743728 cites W2103314023 @default.
• W2116743728 cites W2107066237 @default.
• W2116743728 cites W2109870705 @default.
• W2116743728 cites W2112500845 @default.
• W2116743728 cites W2117091532 @default.
• W2116743728 cites W2118324893 @default.
• W2116743728 cites W2119104567 @default.
• W2116743728 cites W2120902492 @default.
• W2116743728 cites W2122523609 @default.
• W2116743728 cites W2156829363 @default.
• W2116743728 cites W2162064324 @default.
• W2116743728 cites W2170915201 @default.
• W2116743728 cites W339849909 @default.
• W2116743728 doi "https://doi.org/10.1073/pnas.1419945112" @default.
• W2116743728 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4284599" @default.
• W2116743728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25518861" @default.
• W2116743728 hasPublicationYear "2014" @default.
• W2116743728 type Work @default.
• W2116743728 sameAs 2116743728 @default.
• W2116743728 citedByCount "195" @default.
• W2116743728 countsByYear W21167437282015 @default.
• W2116743728 countsByYear W21167437282016 @default.
• W2116743728 countsByYear W21167437282017 @default.
• W2116743728 countsByYear W21167437282018 @default.
• W2116743728 countsByYear W21167437282019 @default.
• W2116743728 countsByYear W21167437282020 @default.
• W2116743728 countsByYear W21167437282021 @default.
• W2116743728 countsByYear W21167437282022 @default.
• W2116743728 countsByYear W21167437282023 @default.
• W2116743728 crossrefType "journal-article" @default.
• W2116743728 hasAuthorship W2116743728A5015481124 @default.
• W2116743728 hasAuthorship W2116743728A5018020732 @default.
• W2116743728 hasAuthorship W2116743728A5018268636 @default.
• W2116743728 hasAuthorship W2116743728A5044615289 @default.
• W2116743728 hasAuthorship W2116743728A5052538293 @default.
• W2116743728 hasAuthorship W2116743728A5054673621 @default.
• W2116743728 hasAuthorship W2116743728A5060458363 @default.
• W2116743728 hasAuthorship W2116743728A5065620364 @default.
• W2116743728 hasAuthorship W2116743728A5070557615 @default.
• W2116743728 hasAuthorship W2116743728A5073015383 @default.
• W2116743728 hasAuthorship W2116743728A5077172319 @default.
• W2116743728 hasAuthorship W2116743728A5083959244 @default.
• W2116743728 hasBestOaLocation W21167437281 @default.
• W2116743728 hasConcept C104317684 @default.
• W2116743728 hasConcept C12554922 @default.
• W2116743728 hasConcept C126725582 @default.
• W2116743728 hasConcept C159047783 @default.
• W2116743728 hasConcept C174510640 @default.
• W2116743728 hasConcept C185592680 @default.
• W2116743728 hasConcept C190062978 @default.
• W2116743728 hasConcept C202878990 @default.
• W2116743728 hasConcept C2522874641 @default.
• W2116743728 hasConcept C2780114586 @default.
• W2116743728 hasConcept C2780879997 @default.
• W2116743728 hasConcept C3013748606 @default.
• W2116743728 hasConcept C55493867 @default.
• W2116743728 hasConcept C59157529 @default.
• W2116743728 hasConcept C70721500 @default.
• W2116743728 hasConcept C86803240 @default.
• W2116743728 hasConcept C95444343 @default.
• W2116743728 hasConceptScore W2116743728C104317684 @default.
• W2116743728 hasConceptScore W2116743728C12554922 @default.
• W2116743728 hasConceptScore W2116743728C126725582 @default.
• W2116743728 hasConceptScore W2116743728C159047783 @default.

• next