FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116774122> ?p ?o ?g. }

• W2116774122 endingPage "52" @default.
• W2116774122 startingPage "46" @default.
• W2116774122 abstract "The function of bone marrow (BM) stromal thrombopoietin (TPO) in megakaryopoiesis remains unknown. In the present study we attempted to clarify the pathophysiological implications of stromal TPO in normal subjects (NS) and in patients with idiopathic thrombocytopenic purpura (ITP), aplastic anemia (AA), and essential thrombocythemia (ET) by measuring TPO concentrations in BM and peripheral blood (PB) and by estimating the levels of stromal TPO mRNA with TaqMan fluorescence-based post–reverse transcription-polymerase chain reaction product detection system. The results showed that TPO concentrations in PB were significantly elevated in patients with ITP (34.9 ± 11.7 pg/mL) and AA (364.1 ± 153.5 pg/mL) but within normal range in patients with ET (each 20.0 and 22.1; NS, 22.1 ± 8.2 pg/mL). In all subjects, the TPO concentrations in BM correlated well with the PB levels, and the former were consistently higher than the latter. The concentrations of TPO in BM also correlated with the levels of TPO mRNA in stromal cells. Furthermore, expression levels of TPO mRNA clearly correlated with megakaryocyte counts in NS and patients with ITP, indicating that stromal TPO actually enhances megakaryopoiesis. Thus, our results in the present study indicate that TPO from BM stromal cells is considered to play an essential role for megakaryopoiesis under various patho-physiological conditions." @default.
• W2116774122 created "2016-06-24" @default.
• W2116774122 creator A5000591714 @default.
• W2116774122 creator A5007136213 @default.
• W2116774122 creator A5009062230 @default.
• W2116774122 creator A5019764276 @default.
• W2116774122 creator A5025082206 @default.
• W2116774122 creator A5032043237 @default.
• W2116774122 creator A5041787620 @default.
• W2116774122 creator A5054498346 @default.
• W2116774122 creator A5061501164 @default.
• W2116774122 creator A5064684165 @default.
• W2116774122 creator A5066847416 @default.
• W2116774122 creator A5090634106 @default.
• W2116774122 date "1998-07-01" @default.
• W2116774122 modified "2023-10-16" @default.
• W2116774122 title "Concentrations of Thrombopoietin in Bone Marrow in Normal Subjects and in Patients With Idiopathic Thrombocytopenic Purpura, Aplastic Anemia, and Essential Thrombocythemia Correlate With Its mRNA Expression of Bone Marrow Stromal Cells" @default.
• W2116774122 cites W101263417 @default.
• W2116774122 cites W1693659057 @default.
• W2116774122 cites W1876681729 @default.
• W2116774122 cites W1890881866 @default.
• W2116774122 cites W1965375035 @default.
• W2116774122 cites W1983612778 @default.
• W2116774122 cites W1998365820 @default.
• W2116774122 cites W2038818733 @default.
• W2116774122 cites W2040996827 @default.
• W2116774122 cites W2086793358 @default.
• W2116774122 cites W2092323417 @default.
• W2116774122 cites W2093758335 @default.
• W2116774122 cites W2134859040 @default.
• W2116774122 cites W2135373727 @default.
• W2116774122 cites W2145684092 @default.
• W2116774122 cites W2258879728 @default.
• W2116774122 cites W2260183312 @default.
• W2116774122 cites W2276322160 @default.
• W2116774122 cites W2412943138 @default.
• W2116774122 cites W29651041 @default.
• W2116774122 cites W4233779632 @default.
• W2116774122 cites W80609826 @default.
• W2116774122 doi "https://doi.org/10.1182/blood.v92.1.46.413k44_46_52" @default.
• W2116774122 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9639498" @default.
• W2116774122 hasPublicationYear "1998" @default.
• W2116774122 type Work @default.
• W2116774122 sameAs 2116774122 @default.
• W2116774122 citedByCount "92" @default.
• W2116774122 countsByYear W21167741222013 @default.
• W2116774122 countsByYear W21167741222014 @default.
• W2116774122 countsByYear W21167741222015 @default.
• W2116774122 countsByYear W21167741222016 @default.
• W2116774122 countsByYear W21167741222017 @default.
• W2116774122 countsByYear W21167741222019 @default.
• W2116774122 countsByYear W21167741222020 @default.
• W2116774122 countsByYear W21167741222023 @default.
• W2116774122 crossrefType "journal-article" @default.
• W2116774122 hasAuthorship W2116774122A5000591714 @default.
• W2116774122 hasAuthorship W2116774122A5007136213 @default.
• W2116774122 hasAuthorship W2116774122A5009062230 @default.
• W2116774122 hasAuthorship W2116774122A5019764276 @default.
• W2116774122 hasAuthorship W2116774122A5025082206 @default.
• W2116774122 hasAuthorship W2116774122A5032043237 @default.
• W2116774122 hasAuthorship W2116774122A5041787620 @default.
• W2116774122 hasAuthorship W2116774122A5054498346 @default.
• W2116774122 hasAuthorship W2116774122A5061501164 @default.
• W2116774122 hasAuthorship W2116774122A5064684165 @default.
• W2116774122 hasAuthorship W2116774122A5066847416 @default.
• W2116774122 hasAuthorship W2116774122A5090634106 @default.
• W2116774122 hasConcept C109159458 @default.
• W2116774122 hasConcept C126322002 @default.
• W2116774122 hasConcept C134018914 @default.
• W2116774122 hasConcept C16930146 @default.
• W2116774122 hasConcept C203014093 @default.
• W2116774122 hasConcept C2776958478 @default.
• W2116774122 hasConcept C2777863708 @default.
• W2116774122 hasConcept C2777918643 @default.
• W2116774122 hasConcept C2779705218 @default.
• W2116774122 hasConcept C2779771385 @default.
• W2116774122 hasConcept C2780007613 @default.
• W2116774122 hasConcept C2780076729 @default.
• W2116774122 hasConcept C2781057849 @default.
• W2116774122 hasConcept C2781440808 @default.
• W2116774122 hasConcept C28328180 @default.
• W2116774122 hasConcept C54355233 @default.
• W2116774122 hasConcept C71924100 @default.
• W2116774122 hasConcept C86803240 @default.
• W2116774122 hasConcept C89560881 @default.
• W2116774122 hasConceptScore W2116774122C109159458 @default.
• W2116774122 hasConceptScore W2116774122C126322002 @default.
• W2116774122 hasConceptScore W2116774122C134018914 @default.
• W2116774122 hasConceptScore W2116774122C16930146 @default.
• W2116774122 hasConceptScore W2116774122C203014093 @default.
• W2116774122 hasConceptScore W2116774122C2776958478 @default.
• W2116774122 hasConceptScore W2116774122C2777863708 @default.
• W2116774122 hasConceptScore W2116774122C2777918643 @default.
• W2116774122 hasConceptScore W2116774122C2779705218 @default.
• W2116774122 hasConceptScore W2116774122C2779771385 @default.
• W2116774122 hasConceptScore W2116774122C2780007613 @default.
• W2116774122 hasConceptScore W2116774122C2780076729 @default.
• W2116774122 hasConceptScore W2116774122C2781057849 @default.

• next